The entire world is facing the stiff challenge of COVID-19 pandemic. To overcome the spread of this highly infectious disease, several short-sighted strategies were adopted such as the use of broad-spectrum antibiotics and antifungals. However, the misuse and/or overuse of antibiotics have accentuated the emergence of the next pandemic: Antimicrobial resistance (AMR). It is believed that pathogens

In this paper, a novel decentralized leader-follower control scheme for multi–agent systems is devised, where each agent communicates only with a subset of neighboring mates. The goal is to track assigned trajectories for the centroid and the formation of the system. The desired trajectories are known only by a subset of agents, named leaders: the other agents, the followers, are required to estim

We derive the order p 8 Lagrangian of odd intrinsic parity for mesonic chiral perturbation theory, and provide the resulting operator basis in the supplementary material. Neglecting the non-zero singlet trace, we find 999 operators for a general number of quark flavours Nf , 705 for Nf = 3 and 92 for Nf = 2. Our numbers agree with those obtained through the Hilbert series approach in the literatur

Purpose: Multiple vendors are currently offering artificial intelligence (AI) computer-aided systems for triage detection, diagnosis, and risk prediction of breast cancer based on screening mammography. There is an imminent need to establish validation platforms that enable fair and transparent testing of these systems against external data. Approach: We developed validation of artificial intellig

Microtubules are dynamic intracellular fibers that have been observed experimentally to undergo spontaneous self-alignment. We formulate a three-dimensional (3D) mean-field theory model to analyze the nematic phase transition of microtubules growing and interacting within a 3D space, then make a comparison with computational simulations. We identify a control parameter Geff and predict a unique cr

Within the lichen family Teloschistaceae, a high number of genera are restricted to the extreme southern part of the Southern Hemisphere. The taxonomy and phylogeny of the southern genus Gondwania have been analyzed based upon fieldwork in Antarctica, Patagonia, New Zealand and Tasmania and subsequent studies including molecular methods. Five species are accepted in the genus Gondwanea including G

A recent meta-analysis on the political impact of the Sustainable Development Goals (SDGs) has shown that these global goals are moving political processes forward only incrementally, with much variation across countries, sectors and governance levels. Consequently, the realization of the 2030 Agenda for Sustainable Development remains uncertain. Against this backdrop, this article explores where

Purpose: To describe the rationale and design of the VOYAGER (NCT05476926) study, which aims to investigate the safety and effectiveness of faricimab and the Port Delivery System with ranibizumab (PDS) for neovascular age-related macular degeneration (nAMD) or diabetic macular edema (DME) in clinical practice. VOYAGER also aims to understand drivers of clinical practice treatment outcomes by gaini

BackgroundThe problem with substandard and falsified (SF) medical products may grow in high-income countries when e-commerce of medicines increases. Unauthorized websites offer medicines of insufficient quality. This underscores the importance of evaluating how the problem with SF medical products can be prevented from escalating. However, little is known about what knowledge and experience profes

The main purpose of this project is to investigate and understand defense lawyers' use of dramaturgy and emotions during court proceedings, as well as how these strategies are employed in their collaboration with clients. Additionally, the project aims to examine the influence of status and power dynamics on defense lawyers' emotions and emotion management in court. The material comprises

The present document was issued by a diverse group of scholars on behalf of The European Association of Health Law (EAHL) Interest Group on Supranational Biolaw, and as part of Stakeholder Feedback on the current draft of General Recommendation N° 37 on racial discrimination in the enjoyment of the right to health (GR37). The EAHL Interest Group on Supranational Biolaw supports the Committee’s eff

Ensuring that the existing social inequalities of the current energy system are not transferred to the new system is crucial for the transition towards a low-carbon economy. This is the domain of energy justice—a normative and evaluative framework that has been applied extensively throughout the past decade for understanding the perspective of disadvantaged energy users. However, less attention ha

Importance: Clonal hematopoiesis (CH) with acquired pathogenic variants in myeloid leukemia driver genes is common in older adults but of unknown prognostic value. Objective: To investigate the prevalence of CH and the utility of the CH risk score (CHRS) in estimating all-cause and disease-specific mortality in older adults with CH. Design, Setting, and Participants: This population-based prospect

Purpose: To report on the occurrence of postoperative visual axis opacification (VAO) in children younger than 5 years of age operated for cataract in Sweden, and to analyse correlations with age at surgery and surgical method. Methods: Data were derived from the Swedish Pediatric Cataract Register (PECARE). All children operated on between 1 January 2007 and 31 December 2020 were included. Follow

Based on a review of the correspondence between Swedish diplomats in the Baltic States and the Swedish Foreign Ministry for the years 1938–1940, the purpose of this article is, firstly, to elaborate a framework for the analysis of intelligence reporting in times of crisis, secondly, to investigate how the Swedish diplomats in the Baltic States went about to report intelligence, and thirdly, to tryBased on a review of the correspondence between Swedish diplomats in the Baltic States and the Swedish Foreign Ministry for the years 1938–1940, the purpose of this article is, firstly, to elaborate a framework for the analysis of intelligence reporting in times of crisis, secondly, to investigate how the Swedish diplomats in the Baltic States went about to report intelligence, and thirdly, to try

Objective: The primary aim of this study was to examine the association between the different predicted phenotypes of the polymorphic CYP2D6 gene and the prevalence of adverse drug reactions in patients suffering from depressive disorders. The secondary aim was to investigate if comedication with CYP2D6 inhibitors resulted in more adverse drug reactions due to phenoconversion. Methods: Between Jan

The Real-World Implementation, Deployment, and Validation of Early Detection Tools and Lifestyle Enhancement (AD-RIDDLE) project, recently launched with the support of the EU Innovative Health Initiative (IHI) public-private partnership and UK Research and Innovation (UKRI), aims to develop, test, and deploy a modular toolbox platform that can reduce existing barriers to the timely detection, and