A neurological wake-up test in the neurointensive care unit : Pros and cons
Traumatic brain injury (TBI) induces a marked systemic biochemical stress response with the release of several stress-related hormones including cortisol and the catecholamines. A major aim of using continuous sedation in the neurointensive care unit (NIC) unit is to attenuate the TBI-induced stress response via reduction of the cerebral energy metabolic demands. In the era of modern multimodality