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Cyclic nucleotide signalling systems in vascular smooth muscle cells and immune system cells with special reference to phosphodiesterases PDE3 and PDE4

Popular Abstract in Swedish Bakgrund: Signalsystem Alla flercelliga organismer är beroende av informationsöverföring mellan celler. Det behövs signaler från andra celler för att reglera tillväxt, ämnesomsättning m. fl. funktioner i olika vävnader. Oftast överförs signalerna via kemiska ämnen som antingen verkar i hela kroppen (hormoner) eller lokalt. När dessa ämnen når målcellen, binds de till eThe cyclic nucleotide signalling systems are important in vascular smooth muscle and in the immune system, and are of interest from a pharmacological point of view. Drugs which interfere with the cyclic nucleotide levels have profound effects on heart, blood vessels and airways and have actual or potential use in several important diseases, such as heart failure, hypertension, arteriosclerosis, as

Reliability Based Design of Fire Exposed Concrete Structures

During the last ten years a rapid progress has been made in the development of analytical methods for a fire engineering design of load bearing structures and structural members. In a long-term perspective, the development then goes towards an analytical design, directly based on a natural fire exposure, specified with regard to the combustion characteristics of the fire load and the geometrical,

Piledal and Svarte. A Comparison Between Two Late Bronze Age Cemeteries in Scania

Svarte and Piledal are typical Scanian Late Bronze Age cremation cemeteries.The Piledal cemetery has the quality of an enclosed entity used by a limited group of people. Svarte, on the other hand, is a more diffuse conglomeration of burials spread over a wider area. The article also contains a discussion of the impact of excavation methods and find circumstances on archaeological interpretation.

Legal limitations on the communication between the parties in public procurement of PPP

The European public procurement regulation has been described as a restrictive force on PPP projects, especially in countries which employ a strict interpretation of the directives. One major limitation brought forward has been the restrictions on negotiations during the procurement procedure. In the literature it has been suggested that the negotiation would improve PPP performance because it all

Computerization of the Control Function in a Process Industry: A Case Study

Computerization of control room functions changes the work for the operators to a great extent. Their mental picture of the process, their possibilities to control the process for productivity and quality, the work content, the physical and the social working environment are examples of conditions which are changed one way or another. In order to be able to control the computerization process in a

Service Orchestration with OPC UA in a Graphical Control Language

Production plants need to be set up and reconfigured faster to fulfill increasing market demands. Highly flexible automation systems are needed and a promising approach is Service Oriented Architecture (SOA) which has recently received much attention in both academia and industry. OPC Unified Architecture (OPC UA), the next generation of the de facto standard for interoperability in the automation

Kommunikationsträning i civilingenjörsprogrammen

At the Faculty of Engineering at Lund University, two of the engineering programmes have decided to strengthen and systematise the students’ communication training during the curriculum. The project addresses two different levels: the engineering teachers of the programme are offered further education while the programme managers are responsible for the progression during the curriculum. The teach