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Anoxic and hypoxic environments serve as habitats for diverse microorganisms, including unicellular eukaryotes (protists) and prokaryotes. To thrive in low-oxygen environments, protists and prokaryotes often establish specialized metabolic cross-feeding associations, such as syntrophy, with other microorganisms. Previous studies show that the breviate protist Lenisia limosa engages in a mutualisti
Interdisciplinary dialogues between political history, environmental history, and the history of science and technology have significantly expanded in recent years. In this context, research on engineers as a key professional group in the material construction of the state has addressed both the political and material dimensions of their work, particularly during the Francoist dictatorship. Howeve
We study the single-photon purity of a resonantly driven single-photon source in the realistic scenario where the excitation laser pulse can leak into the detection path. We find that the duration of the excitation pulse strongly influences the quality of the single-photon source. We calculate the influence of this on the effective parameters describing the most relevant properties, including the
Two major debates frame Arctic prehistory: the emergence of specialized maritime economies that support sedentism and growing socio-political complexity, and the role of these economies in the transition from Paleo-Inuit to Neo-Inuit traditions. This shift, originating in the Bering Strait, led to Thule Inuit dispersal across the Arctic, impacting Indigenous communities today. However, understandi
The incidence of melanoma is rising, increasing the need for efficient diagnostics. Excisional biopsy and histopathology remain the “gold standard” but often require multiple surgical incisions due to limitations in making a visual assessment of melanoma borders either by eye or using dermatoscopy. This challenge partly arises from the inability to non-invasively produce the necessary spectral con
The idea that some people completely lack inner speech is of both scientific and popular interest. In a recent study, Nedergaard and Lupyan compared self-reporting high and low inner-speech-prevalence groups and found that participants in the low-prevalence group performed worse on a verbal working memory test and responded more slowly and less accurately during rhyme judgments. These results repr
Background: In this study we included patients with hereditary angioedema (HAE) caused by decreased levels of C1 inhibitor (HAE-C1INH). An increased risk of autoimmune disorders, particularly systemic lupus erythematosus (SLE), has been reported in HAE-C1INH. This suggests that complement consumption affects adaptive immunity. Objective: To investigate lymphocyte subpopulations in relation to dise
Background and purpose — Outcome after gastrocsoleus lengthening in cerebral palsy (CP) is reported to be influenced by type of lengthening, age, CP subtype, and preoperative range of motion (ROM). We examined the development of ankle and knee ROM after 3 types of isolated gastrocsoleus lengthening. Methods — This is a register-based longitudinal cohort study based on data from the Swedish Cerebra
Objectives: Polycystic ovary syndrome (PCOS) is an endocrine disorder in women of fertile age which may also affect the labor market attachment. We investigated labor market attachment trajectories among working age women diagnosed with PCOS. Methods: A cohort of 157,356 women born in 1975–1977 were followed annually between the ages of 30 and 39, using data from Swedish administrative registers.
If there were no Coulomb interaction among electrons, it would be relatively straightforward to solve the many-electron Schrödinger equation. It is, however, precisely this interaction that is at the heart of numerous fascinating phenomena in condensed matter physics such as superconductivity, Kondo physics, magnetism, etc. Due to the large number of electrons in a material being of the order of A
El Niño–Southern Oscillation (ENSO) events, whether in warm or cold phases, that persist for two or more consecutive years (multi-year), are relatively rare. Compared with single-year events, they create cumulative impacts and are linked to extended periods of extreme weather worldwide. Here we combine central Pacific fossil coral oxygen isotope reconstructions with a multimodel ensemble of transi
Autoimmune thyroid disease (AITD) is associated with other autoimmune endocrine diseases such as type 1 diabetes (T1D) and celiac disease (CeD). Thyroid peroxidase autoantibodies (TPOA) are biomarkers of AITD but may also occur in patients with other autoimmune diseases. We examined cross-sectional correlations between TPOA and an array of immune markers in a cohort of 90 children with exclusively
Objectives: To determine clinical characteristics, outcome and occurrence of comorbidities in patients with biopsy-confirmed giant cell arteritis (GCA) treated with intravenous methylprednisolone (IVMP) vs those receiving oral glucocorticoids (OGC) only. Methods: A retrospective study included patients with GCA diagnosed from 2004 through 2019. Clinical and laboratory characteristics, and cumulati
Children with hemophilia have a significantly higher risk of intracranial hemorrhage (ICH) compared to the normal population. Prophylaxis reduces the risk of ICH and earlier initiation of prophylaxis may now be feasible, especially in hemophilia A (HA). The aim of the study is to explore the potential for preventing ICH by earlier start of prophylaxis by assessing the natural course of ICH before
Background: Depression and suicidal behavior have been linked to increased blood-brain barrier (BBB) permeability. Platelet-derived growth factor receptor beta (PDGFR-β) is widely expressed in pericytes and promotes BBB integrity. Here, we investigated cerebrospinal fluid (CSF) levels of PDGFR-β in suicide attempters and healthy controls and correlated PDGFR-β to depression symptom severity. Metho
Aims The REDUCE-AMI trial showed that beta-blockers in patients with preserved left ventricular ejection fraction (LVEF) after acute myocardial infarction (AMI) had no effect on mortality or cardiovascular outcomes. The aim of this substudy was to evaluate whether global longitudinal strain (GLS) is a better prognostic marker than LVEF, and if beta-blockers have a beneficial effect in patients wit
