Polarization State of Macrophages Affects Their Expression of Upstream TH2-Cytokines and Interferon-Beta Signalling Pathway in Response to Rhinovirus Infection
Introduction: TH2-upstream cytokines (IL-33, IL-25 and TSLP) have emerged as key cytokines in the promotion of allergic asthma. Macrophages (Mϕs) play an important role in the pathogenesis of asthma both in the inflammatory and resolution phases of the disease. Mϕs can acquire different phenotypes depending on their microenvironment. Our aim was to investigate the difference in expression of TH2-u