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THE Gaia-ESO Survey : Metal-rich bananas in the bulge

We analyze the kinematics of ∼2000 giant stars in the direction of the Galactic bulge, extracted from the Gaia-ESO survey in the region -10° ≲ l≲ 10° and -11° ≲ b ≲ -3°. We find distinct kinematic trends in the metal-rich ([M H] > 0) and metal-poor ([M H]

The origin and evolution of r - and s -process elements in the Milky Way stellar disk

Context. Elements heavier than iron are produced through neutron-capture processes in the different phases of stellar evolution. Asymptotic giant branch (AGB) stars are believed to be mainly responsible for elements that form through the slow neutron-capture process, while the elements created in the rapid neutron-capture process have production sites that are less understood. Knowledge of abundan

The Gaia -ESO Survey : Sodium and aluminium abundances in giants and dwarfs: Implications for stellar and Galactic chemical evolution

Context. Stellar evolution models predict that internal mixing should cause some sodium overabundance at the surface of red giants more massive than ~1.5-2.0 M⊙. The surface aluminium abundance should not be affected. Nevertheless, observational results disagree about the presence and/or the degree of Na and Al overabundances. In addition, Galactic chemical evolution models adopting different stel

The Gaia-ESO Survey: A lithium-rotation connection at 5 Myr?

Context. The evolution of lithium abundance in cool dwarfs provides a unique probe of nonstandard processes in stellar evolution. Aims. We investigate the lithium content of young low-mass stars in the 5 Myr old, star forming region NGC 2264 and its relationship with rotation. Methods. We combine lithium equivalent width measurements (EW(Li)) from the Gaia-ESO Survey with the determination of rota

Survival of habitable planets in unstable planetary systems

Many observed giant planets lie on eccentric orbits. Such orbits could be the result of strong scatterings with other giant planets. The same dynamical instability that produces giant planet scatterings can also alter the orbits of terrestrial planets. For example, a habitable rocky planet in the system can be ejected or transported to an orbit outside the habitable zone. Therefore, there is a lin

Människan som biologiskt reservmaterial : Ninni Holmqvists dystopi Enhet

I den dystopiska skildringen Enhet (2006) gestaltar Ninni Holmqvist ett alternativt svenskt samhälle där människor som inte är samhällsnyttiga används som biologiskt reservmaterial för att bota sjukdomar hos andra, behövda människor. Samhället har blivit totalitärt, människor bedöms efter produktivitet och organdonation har blivit ett tvång för vissa grupper. I den här artikeln diskuterar jag hur

Socioeconomic inequalities in knee pain, knee osteoarthritis, and health-related quality of life : a population-based cohort study in southern Sweden

Objectives: To determine socioeconomic inequalities in frequent knee pain (FKP), knee osteoarthritis (OA), and associated health-related quality of life (HRQoL) in Sweden. Method: In 2007 a postal questionnaire about knee pain was sent to a random sample of 10 000 residents of Malmö, Sweden (7402 individuals responded). Subjects reporting pain with duration ≥ 4 weeks in one or both knees in the pa

Occupational balance in health professionals in Sweden

Background: Health care employees are often women, a group that has high degrees of sick leave and perhaps problems attaining occupational balance. However, people think differently about their everyday activities and it is therefore important to take their perceptions into account but occupational balance has not yet been measured in health professionals. The aim was to describe occupational bala

Haemophilia treatment in 2030

Introduction: Looking into the future is difficult and sometimes hazardous. A reliable look into haemophilia treatment in 2030 should be based on history and contemporary progress as well as dilemmas. Today, the issue of inhibitors overshadows the entire haemophilia community together with lack of treatment for large parts of the world's persons with haemophilia. Aims: The aim of this paper was to

Low-grade inflammation, oxidative stress and risk of invasive post-menopausal breast cancer - A nested case-control study from the Malmö diet and cancer cohort

Objective: Although cancer promotes inflammation, the role of inflammation in tumor-genesis is less well established. The aim was to examine if low-grade inflammation is related to post-menopausal breast cancer risk, and if obesity modifies this association. Methods; In the Malmo Diet and Cancer cohort, a nested case-control study was defined among 8,513 women free of cancer and aged 55.73 years a

Metabolic profiling of systemic lupus erythematosus and comparison with primary Sjögren's syndrome and systemic sclerosis

Systemic lupus erythematosus (SLE) is a chronic inflammatory autoimmune disease which can affect most organ systems including skin, joints and the kidney. Clinically, SLE is a heterogeneous disease and shares features of several other rheumatic diseases, in particular primary Sjögrens syndrome (pSS) and systemic sclerosis (SSc), why it is difficult to diagnose The pathogenesis of SLE is not comple

Hydrogen bonds, hydrophobicity forces and the character of the collapse transition

We study the thermodynamic behavior of a model protein with 54 amino acidsthat is designed to form a three-helix bundle in its native state. The model contains three types of amino acids and five to six atoms per amino acid, and has the Ramachandran torsion angles as its only degrees of freedom.The force field is based on hydrogen bonds and effective hydrophobicity forces. We study how the charact

Three-helix-bundle protein in a Ramachandran model

We study the thermodynamic behavior of a model protein with 54 amino acids that forms a three-helix bundle in its native state. The model contains three types of amino acids and five to six atoms per amino acid and has the Ramachandran torsional angles phi(i), psi(i) as its degrees of freedom. The force field is based on hydrogen bonds and effective hydrophobicity forces. For a suitable choice of

On hydrophobicity correlations in protein chains

We study the statistical properties of hydrophobic/polar model sequences with unique native states on the square lattice. It is shown that this ensemble of sequences differs from random sequences in significant ways in terms of both the distribution of hydrophobicity along the chains and total hydrophobicity. Whenever statistically feasible, the analogous calculations are performed for a set of re

Design of sequences with good folding properties in coarse-grained protein models

BACKGROUND: Designing amino acid sequences that are stable in a given target structure amounts to maximizing a conditional probability. A straightforward approach to accomplishing this is a nested Monte Carlo where the conformation space is explored over and over again for different fixed sequences; this requires excessive computational demand. Several approximate attempts to remedy this situation

Binary assignments of amino acids from pattern conservation

We have developed a simple optimization procedure for assigning binary values to amino acids. The binary values are determined by a maximization of the degree of pattern conservation in groups of closely related protein sequences. The maximization is carried out at fixed composition. For compositions approximately corresponding to an equipartition of the residues, the optimal encoding is found to