Functional divergence of MdpS and MdpS2 reveals mucin-targeting strategies in Streptococcus oralis
Background: Mucin degradation is essential for understanding oral microbial adaptation, yet the enzymes involved remain incompletely understood. Herein, we have characterised two mucin-degrading proteases, MdpS and MdpS2, from the oral commensal Streptococcus oralis. Materials and methods: MdpS2 was characterised using physicochemical assays and substrate profiling and was compared to MdpS. Furthe
