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Psychometric evaluation of the Chinese version of the Person-centred Climate Questionnaire - Staff version (PCQ-S)

OBJECTIVES: The aim of the study was to evaluate the psychometric properties of a Chinese translation of the English version of the Person-centred Climate Questionnaire - Staff version (PCQ-S) for Chinese palliative care staff in a hospital context.DESIGN: This was a cross-sectional design. The 14-item English PCQ-S was translated and backtranslated using established procedures. Construct validity

The carcinogenic air pollutant 3-nitrobenzanthrone induces GC to TA transversion mutations in human p53 sequences

3-Nitrobenzanthrone (3-NBA) is a potent mutagen and a suspected human carcinogen present in particulate matter of diesel exhaust and ambient air pollution. Employing an assay with human p53 knock-in (Hupki) murine embryonic fibroblasts (HUFs), we examined p53 mutations induced by 3-NBA and its active metabolite, N-hydroxy-3-aminobenzanthrone (N-OH-3-ABA). Twenty-nine immortalized cultures (cell li

Toleransens gränser : Religionspolitiska dilemman i det tidiga 1700-talets Sverige och Europa

Var går gränsen för vilka avvikelser från samhällets grundvalar som kan tolereras? När så kallade pietister framträdde i Sverige vid 1700-talets början uppstod en ny problematik kring toleransens gränser i Sveriges historia. Till skillnad från i övriga Europa hade dessförinnan religiösa avvikare inte funnits i någon större omfattning. Pietisterna uppfattades som ett hot mot den gemensamma religion

Modelling an industrial anaerobic granular reactor using a multi-scale approach

The objective of this paper is to show the results of an industrial project dealing with modelling of anaerobic digesters. A multi-scale mathematical approach is developed to describe reactor hydrodynamics, granule growth/distribution and microbial competition/inhibition for substrate/space within the biofilm. The main biochemical and physico-chemical processes in the model are based on the Anaero

Perspectives for surrogate safety studies in east-European countries

The road safety development in East-European countries follows in general the trends of the western countries, even though there is a time lag. The fatality numbers are decreasing, though the improvements for the vulnerable road users are less impressive compared to other road user categories. The traditional road safety analysis based on accident history has many limitations related to accident u

Function and flexibility of object exploration in kea and new caledonian crows

A range of non-human animals frequently manipulate and explore objects in their environment, which may enable them to learn about physical properties and potentially form more abstract concepts of properties such as weight and rigidity. Whether animals can apply the information learned during their exploration to solve novel problems, however, and whether they actually change their exploratory beh

Climbing the cosmic ladder with stellar twins in RAVE with Gaia

We apply the twin method to determine parallaxes to 232 545 stars of the RAVE survey using the parallaxes of Gaia DR1 as a reference. To search for twins in this large data set, we apply the t-student stochastic neighbour embedding projection that distributes the data according to their spectral morphology on a two-dimensional map. From this map, we choose the twin candidates for which we calculat

Erfarenhetsåterföring vid renovering

Nationellt Renoveringscentrum (NRC) bildades 2013 för att arbeta med kunskapshöjning och informationsspridning om en effektiv renoveringsprocess. Centret siktar på att samla och föra vidare kunskap om hur renovering av befintlig bebyggelse kan genomföras både effektivt för involverade aktörer såväl som socialt, ekonomiskt och miljömässigt hållbart för samhället. Kunskap från både akademi och närin

Pioneers for the Basic Understanding of Usher syndrome

After the first description of the inherited nature of bimodal deaf-blindness disease in mid nineteenth century by pioneering ophthalmologists Albrecht von Graefe (May 22, 1828 ± July 20, 1870) and Richard Liebreich (June 30, 1830 - January 19, 1917) followed by its confirmation in early twentieth century from a larger number of patients by another pioneer ophthalmologist Charles Howard Usher (Mar

Sömnstörningar hos barn

Som ett led i regeringsuppdraget att ”Utvidga kunskapen om barns läkemedel och deras användning” anordnade Läkemedelsverket 2012 ett möte med representanter för barn- och ungdomspsykiatrin. Syftet var att identifiera kunskapsluckor samt föreslå speciella läkemedelsområden där det fanns behov av att sammanställa kunskap. Behandling av sömnstörningar hos barn var ett område som prioriterades.

Targeted uptake of folic acid-functionalized iron oxide nanoparticles by ovarian cancer cells in the presence but not in the absence of serum

Targeted delivery of nanoparticles to cells or tissues of interest is arguably the "holy grail" of nanomedicine. Using primary human macrophages and ovarian cancer cells, we evaluated the biocompatibility and specific targeting of folic acid (FA)-conjugated iron oxide nanoparticles with organic [poly(ethylene glycol), PEG] or inorganic (SiO2) intermediate surface coatings. Reduction of folate rece

Motivating the contributions : An Open Innovation perspective on what to share as Open Source Software

Open Source Software (OSS) ecosystems have reshaped the ways how software-intensive firms develop products and deliver value to customers. However, firms still need support for strategic product planning in terms of what to develop internally and what to share as OSS. Existing models accurately capture commoditization in software business, but lack operational support to decide what contribution s

Numerical Estimation of Asymmetry of In-Cylinder Flow in a Light Duty Direct Injection Engine with Re-Entrant Piston Bowl

Partially premixed combustion (PPC) can be applied to decrease emissions and increase fuel efficiency in direct injection, compression ignition (DICI) combustion engines. PPC is strongly influenced by the mixing of fuel and oxidizer, which for a given fuel is controlled mainly by (a) the fuel injection, (b) the in-cylinder flow, and (c) the geometry and dynamics of the engine. As the injection tim

Evaluation of image quality and radiation dose of abdominal dual-energy CT

Background Dual-energy computed tomography (DECT) has conceptually been known since the late 1970s and commercially available as dual-source CT (DSCT) systems since 2006; however, the technique has not yet seen widespread implementation in routine protocols. Part of the cause for this is likely due to misconceptions about radiation dose and/or image quality when using DECT. Purpose To compare imag