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Effects of diabetes definition on global surveillance of diabetes prevalence and diagnosis: a pooled analysis of 96 population-based studies with 331288 participants

Background Diabetes has been defined on the basis of different biomarkers, including fasting plasma glucose (FPG), 2-h plasma glucose in an oral glucose tolerance test (2hOGTT), and HbA(1c). We assessed the effect of different diagnostic definitions on both the population prevalence of diabetes and the classification of previously undiagnosed individuals as having diabetes versus not having diabet

Formation of carbonated apatite particles from a supersaturated inorganic blood serum model

Pathological calcification is common among for instance dialysis patients, and this causes an increase in mortality risk. An elevated serum phosphate concentration among those patients strongly correlates to this increase. In this work investigations of the conditions, composition, crystallinity and morphology of in vitro calcification are performed and related to results from in vivo studies. The

From High-Level Task Descriptions to Executable Robot Code

For robots to be productive co-workers in the manufacturing industry, it is necessary that their human colleagues can interact with them and instruct them in a simple manner. The goal of our research is to lower the threshold for humans to instruct manipulation tasks, especially sensorcontrolled assembly. In our previous work we have presented tools for high-level task instruction, while in this p

On the Modeling of Premixed Combustion under Varying Equivalence Ratios

This thesis deals with numerical simulation of reactive flows. The numerical method is three dimensional and unsteady, which allows for spatial and temporal resolution of most of the scales of the fluid motion and the reaction process. In the turbulent cases studied, scales down to Taylor scales are resolved. Hence, it can be considered to be a large eddy simulation, LES. In the laminar cases stud

A key role for orexin in panic anxiety

Panic disorder is a severe anxiety disorder with recurrent, debilitating panic attacks. In individuals with panic disorder there is evidence of decreased central gamma-aminobutyric acid (GABA) activity as well as marked increases in autonomic and respiratory responses after intravenous infusions of hypertonic sodium lactate(1-3). In a rat model of panic disorder, chronic inhibition of GABA synthes

Short- and long-term measurements of resonance frequencies on prestressed concrete beams

Currently, no method exists for determining the prestress forces in prestressed concrete structures. According to the theory of acoustoelasticity, the modulus of elasticity of concrete is stress dependent, which means that the resonance frequency of a concrete structure also is stress dependent. In this study, both short-term and long-term measurements of the resonance frequencies of four prestres

An MM/3D-RISM approach for ligand binding affinities.

We have modified the popular MM/PBSA or MM/GBSA approaches (molecular mechanics for a biomolecule, combined with a Poisson-Boltzmann or generalized Born electrostatic and surface area nonelectrostatic solvation energy) by employing instead the statistical-mechanical, three-dimensional molecular theory of solvation (also known as 3D reference interaction site model, or 3D-RISM-KH) coupled with mole

Preparation and encapsulation properties of double Pickering emulsions stabilized by quinoa starch granules

Double emulsions have potential applications in the food, cosmetic and pharmaceutical industries as vehicles for encapsulation and delivery of nutrients during food digestion or as drug release. The major drawback of this type of emulsions is that they are often difficult to stabilize. Particle stabilized emulsions, known as Pickering emulsions, show special features, such as being extremely stabl

Effects of production and market factors on ethanol profitability for an integrated first and second generation ethanol plant using the whole sugarcane as feedstock

Background: Sugarcane is an attractive feedstock for ethanol production, especially if the lignocellulosic fraction can also be treated in second generation (2G) ethanol plants. However, the profitability of 2G ethanol is affected by the processing conditions, operating costs and market prices. This study focuses on the minimum ethanol selling price (MESP) and maximum profitability of ethanol prod

Culture of Corruption

With special reference to India and Indonesia the paper considers a number of methodological issues connected with the study of corruption. These include definitions of corruption, a public administration approach, the bazaar concept vs questions of family, network, and patronage, limitations to corruption, and the political impact.

Nordic Haemophilia Council's Practical Guidelines on Diagnosis and Management of von Willebrand Disease

von Willebrand disease (VWD) is the most common inherited bleeding disorder characterized by spontaneous or tissue injury related, mostly mucocutaneous, bleeding events. VWD affects both males and females and is caused by quantitative or qualitative deficiency of von Willebrand factor. The diagnostic procedure is complicated because VWD is highly heterogeneous, and differential diagnosis from plat

Quantitative genetics research in Zebra Finches: where we are and where to go

The ease with which Zebra Finches can be kept and bred in captivity makes them a suitable model for avian quantitative genetic studies. After a brief introduction to some quantitative genetic concepts, we here provide an up-to-date overview of quantitative genetic studies in Zebra Finches. We discuss what these studies can teach us about the evolutionary and behavioural ecology of Zebra Finches an

Den svenska supply chain-panelen: Supply Chain Performance Measurement, SCPM

Sommaren 2013 etablerades den svenska supply chain-panelen av forskare från Institutionen för teknisk ekonomi och logistik vid Lunds universitet. Panelen består av personer som alla arbetar på ledningsnivå med SC-frågor på olika företag som är verksamma i Sverige. Medlemmarna representerar en god blandning av olika typer av företag inom olika branscher och har gått med på att svara på fyra (4) enk

Radiochromic film imaging spectroscopy of laser-accelerated proton beams

This article reports on an experimental method to fully reconstruct laser-accelerated proton beam parameters called radiochromic film imaging spectroscopy (RIS). RIS allows for the characterization of proton beams concerning real and virtual source size, envelope- and microdivergence, normalized transverse emittance, phase space, and proton spectrum. This technique requires particular targets and

The locus coeruleus Is Directly Implicated in L-DOPA-Induced Dyskinesia in Parkinsonian Rats: An Electrophysiological and Behavioural Study

Despite being the most effective treatment for Parkinson's disease, L-DOPA causes a development of dyskinetic movements in the majority of treated patients. L-DOPA-induced dyskinesia is attributed to a dysregulated dopamine transmission within the basal ganglia, but serotonergic and noradrenergic systems are believed to play an important modulatory role. In this study, we have addressed the role o