Title: Strategic Alignment in Procurement for a Swedish OEM: Supply Chain Management for Enhanced Performance Background: Developing strategies to meet different customer demands and conditions is important for companies to succeed. This thesis explores how to differentiate larger customers demand with the company’s own business objectives in mind for a small procurement organization. Purpose: T

Identification and characterization of CD8+ T-cells is important to determine their role in protecting and clearing viral infections. Here we provide details of the peptide-MHC (pMHC) tetramers-based approach to identify antigen-specific T-cells in human and murine samples. This method provides ex vivo quantifica-tion and functional characterization of T-cells reactive to specific viral antigens d

Duplication of PLP1 (proteolipid protein gene 1) and the subsequent overexpression of the myelin protein PLP (also known as DM20) in oligodendrocytes is the most frequent cause of Pelizaeus-Merzbacher disease (PMD), a fatal leukodystrophy without therapeutic options. PLP binds cholesterol and is contained within membrane lipid raft microdomains. Cholesterol availability is the rate-limiting factor

OBJECTIVE: To monitor serum concentrations of the aggrecan alanine-arginine-glycine-serine (ARGS) neoepitope in a clinical trial of a disintegrin and metalloproteinase with thrombospondin motifs (ADAMTS)-5 inhibition as disease-modifying therapy of knee osteoarthritis, and to investigate relationships between reduction in ARGS and change in cartilage thickness, knee-related pain and function. DESITo monitor serum concentrations of the aggrecan alanine-arginine-glycine-serine (ARGS) neoepitope in a clinical trial of a disintegrin and metalloproteinase with thrombospondin motifs (ADAMTS)-5 inhibition as disease-modifying therapy of knee osteoarthritis, and to investigate relationships between reduction in ARGS and change in cartilage thickness, knee-related pain and function.DesignROCCELLA t

Ice formation remains one of the most poorly represented microphysical processes in climate models. While primary ice production (PIP) parameterizations are known to have a large influence on the modeled cloud properties, the representation of secondary ice production (SIP) is incomplete and its corresponding impact is therefore largely unquantified. Furthermore, ice aggregation is another importa

Understanding how momentum anisotropies arise in small collision systems is important for a quantitative understanding of collectivity in terms of QCD dynamics in small and large collision systems. In this letter we present results for small collision systems from the newly developed parton cascade ALPACA, which faithfully encodes the AMY effective kinetic theory. ALPACA reproduces quantitatively

Identifying key molecular pathways and genes involved in the response to urban pollutants is an important step in furthering our understanding of the impact of urbanisation on wildlife. The expansion of urban habitats and the associated human-introduced environmental changes are considered a global threat to the health and persistence of humans and wildlife. The present study experimentally invest

Economic research on gender gaps in preferences and economic outcomes has focused on variation with respect to sex—a binary classification as either a “man”or “woman.” We validate a novel and simple measure of self-reported continuousgender identity (CGI) and explore whether gender identity correlates with variationin economic decisions and outcomes beyond the relationship with binary sex.We use f

En allmän översikt över handelns historia från stenåldern till idag, ämnad för gymnasieskolan.

Idag är kvinnorna fler än männen på juristutbildningarna och nästan sju av tio antagna till domarutbildningen är kvinnor. De kvinnliga juristerna är i majoritet inom flera juridiska yrken, för hundra år sedan var situationen en helt annan. Från 1870-talet fick kvinnor lov att studera juridik på universiteten, men det var svårt för dem att hitta arbete efter examen. Hindren i deras väg fanns både i

Researchers have long been studying the effects of the modification of friction material compositions on their tribological properties. Predictive models have also been developed, but they are of limited use in the design of new compositions. Therefore, this research aims to investigate the tribological behaviour of single ingredients in friction materials to develop a tribological dataset. This d

When coupled to different applications, a polymer electrolyte fuel cell (PEFC) work at a different operating temperature. In this study, the internal resistance of a PEFC is evaluated by using Electrochemical Impedance Spectroscopy (EIS) at moderate low current density, i.e., 0.5 A/cm2, in the range of 40 – 80°C. The evaluation is carried out considering frequencies between 10kHz and 0.1Hz. An equ

Academic journals, archives, and repositories are seeing an increasing number of questionable research papers clearly produced using generative AI. They are often created with widely available, general-purpose AI applications, most likely ChatGPT, and mimic scientific writing. Google Scholar easily locates and lists these questionable papers alongside reputable, quality-controlled research. Our an

The beam performance of the MAX II storage ring is described by computer simulations. The dynamic aperture reduction due to chromaticity correcting multipoles, higher order multipoles in quadrupoles and dipoles, alignment errors and energy deviations is calculated. The future operation of the storage ring with insertion devices is discussed. The results show that the MAX II storage ring will opera

Here we evaluated the levels of lipid oxidation products, fatty acids, ascorbic acid and colour of Porphyra and Ulva after oven-drying at 40 °C, and during subsequent storage for ≥370 days under light, semi-light and dark conditions. Part of the seaweed was pre-soaked in freshwater or pre-coated with a whey protein mixture. Controls consisted of freeze-dried seaweeds. Throughout storage there was

Mycobacterium sp. (NRRL-B 3683) has been immobilized by adhesion of magnetic materials of submicron size to the bacterial surface. Preparations based on laboratory-prepared magnetic oxide that had been derivatized with hydrophobic octyltrichlorosilane showed the best properties. The magnetically immobilized bacteria were used for side-chain degradation of cholesterol into androsta-1,4-diene-3,17-d

In this review, we present the current status of phenomenological research on constraining the multi-dimensional proton (and nucleus) structure at high energies through studies of the so-called gluon Wigner distributions. We provide a brief pedagogical introduction into the corresponding theoretical definitions and modelling of exclusive and diffractive scattering observables in terms of the Wigne