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Long acting local anaesthetics - a study in rats

Popular Abstract in Swedish Lokalbedövningsmedel ger en god smärtlindring efter centrala och perifera nervblockader. I många kliniska situationer hade det dock varit önskvärt med en längre duration av nervblockaden. De olika delarbetena i denna avhandling fokuserade på detta problem. Indianerna i Syd Amerika har länge känt till att om man tuggar bladen ifrån Erythroxylon Coca så upplev's en bedövLocal anaesthetics provide excellent pain relief after central and peripheral nerve blocks. However, in many clinical situations there is an insufficient duration of action to allow effective treatment of long-term pain with single injection techniques. This problem became the focus of the present studies. The natives in South America used to chew the leaves from Erythroxylon Coca and were well aw

Systematic clinical supervision of home carers working in the care of demented people who are at home: structure, content and effect as experienced by participants

AIM: The aim of this paper is to investigate structure, content and effects of systematic clinical supervision (SCS). BACKGROUND: Home care staff caring for people with dementia were offered SCS because the increasing number of elderly people with dementia increases the demands made on nurses. METHOD: Supervisors (n = 5) and SCS participants (n = 6) were interviewed and an additional 52 SCS partic

Inhibition of leukocyte phagocytosis by serotonin and its possible role in tumor cell destruction

Intraportal tumour cell (TC) injection activates platelets which release serotonin (5-HT). Thrombocytopenia or 5-HT blockade decrease the hepatic lodgement of the injected TCs. A hypothetical explanation of this is 5-HT inhibition of TC killing by phagocytes (e.g. leukocytes and Kupffer cells). In this study, leukocyte phagocytosis was analysed by a chemiluminescence technique at different 5-HT co

Sex pheromone biosynthesis in the pine caterpillar moth, Dendrolimus punctatus (Lepidoptera : Lasiocampidae): pathways leading to Z5-monoene and 5,7-conjugated diene components

Biosynthesis of the sex pheromone components (Z)-5-dodecenol and (Z,E)-5,7-dodecadienol in Dendrolimus punctatus was studied by topical application of deuterium-labeled fatty acids to pheromone glands and subsequent analysis of fatty acyl groups and pheromone components by gas chromatography-mass spectrometry. Our studies suggest that both (Z)-5-dodecenol and (Z,E)-5,7-dodecadienol can be biosynth

Idrott och skallskador. Riktlinjer för omhändertagande och återgång till träning och tävling

Head injuries in sports have received increased attention during the past decade. As explained in this article, the most recent guidelines for the management of head injuries in sports adopted by the American Academy of Neurology (AAN) have been adapted for the Swedish sports society. The guidelines include a grading scale of head injuries in sports, a sideline evaluation to aid physicians, coache

Non-associated plasticity for soils

A brief overview is given of a non-associated plasticity theory developed for soils based on the concept of a characteristic stress state of vanishing incremental dilation, and a calibration procedure using only test data from a standard triaxial test. The capability of the model is illustrated by calibration examples and predictions made for standard triaxial tests at different confining stress l

Dödsstraffet, kyrkan och staten i Sverige från 1700-tal till 1900-tal

This is a study of change in ecclesiastical praxis and theological Irgument concerning the death penalty and the condemned in Sweden, seen in an international perspective and as a part of general change in the society. The execution gave an example of both crime and revenge and of repentance and the possibility of a pious death. This examl)le through secularisation came under attack from two sides

Holocene geomagnetic paleointensities: A blind test of absolute paleointensity techniques and materials

Through several decades of research, absolute paleointensity estimates have been obtained from a wide range of rocks with varying ages, covering the last 3.45 Ga years. These paleointensity data are crucial to study the past geodynamo and the geological evolution of the Earth's deep interior. However, paleointensity data are often difficult to interpret, and on-going discussions concerning the pas

Three major Lyme Borrelia genospecies (Borrelia burgdorferi sensu stricto, B. afzelii and B. garinii) identified by PCR in cerebrospinal fluid from patients with neuroborreliosis in Sweden.

The Lyme Borrelia genospecies Borrelia afzelii and B. garinii have previously been isolated using a culture method in Swedish patients with Lyme borreliosis (LB). There are reports suggesting that the genospecies distribution in human tissue specimens as determined by molecular methods is different from that obtained by culture. In the present study, we developed a nested PCR for detection of Lyme

Solvent effects on rotatory strength tensors. 1. Theory and application of the combined coupled cluster/dielectric continuum model

In this article we present the first theoretical study of solvent effects on the rotatory strength tensor. The system chosen is solvated formaldehyde for which only one tensor element is nonvanishing, and the solvent is modeled as a linear, homogeneous, and isotropic dielectric continuum. We present results using both an equilibrium and a nonequilibrium description of the solvent. Four illustrativ

Knee outcome scales: Basic concepts, review of methods, cross-cultural and linguistic adaptation

In recent years, outcome assessment following different therapeutic procedures has increasingly focused on the patient's perspective. While traditional measures of outcome, including physical examination and imaging diagnostics of the knee are complementary, patient-relevant questionnaires have become more and more important in determining the value of therapeutic procedures. Therefore, there is a