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Huntington's disease (HD) is caused by a polyglutamine expansion in the protein huntingtin and is characterized by intraneuronal inclusions and widespread neuronal death at the late stage of the disease. In research, most of the emphasis has been on understanding the cell death and its mechanisms. Until recently, it was believed that the vast majority, if not all, of the symptoms in HD are a direc
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We evaluated whether urinary excretion of the carboxy terminal domain (NC1) of Type IV collagen is associated with glomerular filtration rate and kidney size in Type I (insulin-dependent) diabetes mellitus (IDDM). Urinary excretion rate of NC1, glomerular filtration rate (GFR), and kidney size were measured in 16 men with Type I diabetes. Their mean age was 33.3 +/- 6.1 years with a duration of di
We have prepared a new type of anion exchanger, which effectively discriminates between RNA and plasmid DNA. The material is based on a Sephacryl S-500 HR matrix provided with quartenary amine anion-exchange groups. A distinguishing feature of the beads is that a thin (2-3 mum) outer layer of the beads lacks ion-exchange groups. In the synthesis of these beads the vinyl groups in the outer layer o
Patients with organic solvent-induced toxic encephalopathy (TE) (n = 13) were followed up seven years after the application of an intervention program. They were also compared with untreated TE patients diagnosed at the same time (n = 26) and with unexposed referents (n = 39). Psychological distress, social function, and coping ability and style were measured with the Symptom Checklist-90, Intervi
We determined the frequency of extra-pair paternity and intraspecific brood parasitism in European Starlings (Sturnus vulgaris) by performing multilocus DNA fingerprinting on 22 complete families from a population in southern Sweden. Among 92 nestlings, we did not detect any successful intraspecific brood parasitism. This confirms observational data that successful intraspecific brood parasitism i
Dopamine (DA) is a neurotransmitter that plays a fundamental role in many aspects of normal brain function. The majority of DA neurons in the brain reside in one region ? the midbrain ? and project axonal connections to specific areas. One of the main target regions of the DA system is the striatum. This connection is known as the nigrostriatal pathway. During early development, a particular popul
In this article we address the problem of projective reconstruction of structure and motion given only image data. In particular we investigate three novel minimal combinations of points and lines over three views, and give complete solutions and reconstruction methods for two of these cases: 'four points and three lines in three views', and 'two points and six lines in three views'. We show that
We estimated total lake plant biomass and primary net production in two shallow Swedish lakes that differ in nutrient loading and plant form dominance. In clearwater Lake Krankesjon (10 mu g chlorophyll a L-1), submerged macrophytes contributed more than phytoplankton and epiphyton to the estimated plant biomass. Estimated net primary production during May to September was 90-130, 1.2, and 14 g C
The equilibrium terrestrial biosphere model BIOME3 simulates vegetation distribution and biogeochemistry, and couples vegetation distribution directly to biogeochemistry. Model inputs consist of latitude, soil texture class, and monthly climate (temperature, precipitation, and sunshine) data on a 0.5 degrees grid. Ecophysiological constraints determine which plant functional types (PFTs) may poten
Popular Abstract in Swedish Avhandlingen undersöker de kontexter inom vilken Malmö Stadsteaters ungdomsgrupp Unga Teatern existerade, bl a kulturpolitik, skol- och läroplansutveckling och reception. Den övergripande frågeställningen är huruvida det under vissa perioder funnits en genomgripande estetik. Nio uppsättningar analyseras med avseende på pjästext, iscensättning, arbetsprocess och receptioThis dissertation investigates whether Unga Teatern, a theatre group for children and youth at Malmö City Theatre, had an aesthetic profile of its own. It focuses on three sections: the theme of fairy tales and myths under the artistic direction of Ronnie Hallgren (19977-83), his staging of English plays (1982 -84) and the avantgarde production for children and youth under the direction of Karin P
The outdoor environment is deteriorating in many tropical cities due to rapid urbanization. This leads to a number of problems related to health and well-being of humans and also negatively affects social and commercial outdoor activities. The creation of thermally comfortable microclimates in urban environments is therefore very important. This paper discusses the influence of street-canyon geome
Objective. To study the distensibility and the diameter of the abdominal aorta and the common carotid artery (CCA) in patients with rheumatoid arthritis (RA), and investigate the relation between mechanical properties of these arteries and disease severity. Methods. One hundred and one patients with RA (33 consecutive cases with extra-articular manifestations, and 68 subjects with non-extra-artic
