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alpha-Phenyl-tert-N-butyl nitrone (PBN) improves functional and morphological outcome after cortical contusion injury in the rat

alpha-Phenyl-tert-N-butyl nitrone (PBN), a potent reactive oxygen species (ROS) scavenger, has shown robust neuroprotective properties in several models of acute brain injury, although not previously evaluated in traumatic brain injury (TBI). In this study, we assessed the potential efficacy of PBN in a weight drop model producing a controlled cortical contusion. Sham operation, mild or severe inj

Single droplet breakup in a rotor-stator mixer

This study presents measurements of droplet transport inside a rotor-stator mixer under turbulent flow conditions and contributes to the understanding of the droplet breakup phenomenon. The measurements contain unique information on droplet breakup down to the limit of equilibrium droplet size. The experimental setup includes a custom-built rotor-stator mixer that provides optical access to the mi

Will You Intermarry Me? : Determinants and Consequences of Immigrant-Native Intermarriage in Contemporary Nordic Settings

This dissertation examines the determinants and consequences of immigrant-native intermarriage in two Nordic countries, Sweden and Denmark, between 1980 and 2011. An increase in immigration during the second half of the twentieth and early twenty-first century in the countries under study was accompanied by an increase in intermarriage. However, the marriages of natives and some immigrant groups a

How young firms achieve growth : reconciling the roles of growth motivation and innovative activities

Growth orientation is important for understanding why some young firms grow but not others, but research remains silent on the intermediary mechanisms mediating the growth orientation–firm growth relationship. We study 282 Swedish firms and show that various innovative activities mediate the growth orientation–firm growth relationship. These mediating innovative activities include informal activit

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Este trabajo se ciñe exclusivamente al testamento literario que los Nobel de Literatura nos han regalado a modo de discurso. El objetivo ha sido desgranar dichos discursos para ver similitudes o diferencias y extraer las pertinentes reflexiones gracias a un material lleno de talento y altamente cualificado por quienes han dedicado sus vidas al servicio de la literatura. El método ha sido analizar

Energy consumption in e-commerce versus conventional trade channels - Insights into packaging, the last mile, unsold products and product returns

The purpose is to analyse and explain factors determining whether conventional trade with stores or e-commerce with home delivery is more energy-efficient. The findings from previous studies are compared in order to identify more general patterns of energy consumption, describe which energy consumption factors (product waste and product returns, buildings, packaging, passenger transport and freigh

IDAC-Dose 2.1, an internal dosimetry program for diagnostic nuclear medicine based on the ICRP adult reference voxel phantoms

Background: To date, the estimated radiation-absorbed dose to organs and tissues in patients undergoing diagnostic examinations in nuclear medicine is derived via calculations based on models of the human body and the biokinetic behaviour of the radiopharmaceutical. An internal dosimetry computer program, IDAC-Dose2.1, was developed based on the International Commission on Radiological Protection

Sensitivity Analysis of Partially Premixed Combustion (PPC) for Control Purposes

Partially Premixed Combustion (PPC) is a promising advanced combustion mode for future engines. In order to investigate the sensitivity of PPC to exhaust gas recirculation (EGR) rate, intake gas temperature, intake gas pressure, and injection timing, these parameters were swept individually at three different loads in a single cylinder diesel engine with gasoline-like fuel.A factor of sensitivity

Tuning growth direction of catalyst-free InAs(Sb) nanowires with indium droplets

The need for indium droplets to initiate self-catalyzed growth of InAs nanowires has been highly debated in the last few years. Here, we report on the use of indium droplets to tune the growth direction of self-catalyzed InAs nanowires. The indium droplets are formed in situ on InAs(Sb) stems. Their position is modified to promote growth in the 〈11-2〉 or equivalent directions. We also show that in

Interstitial F(2)-isoprostane 8-iso-PGF(2α) as a biomarker of oxidative stress after severe human traumatic brain injury

Oxidative stress is a major contributor to the secondary injury process after experimental traumatic brain injury (TBI). The importance of oxidative stress in the pathobiology of human TBI is largely unknown. The F(2)-isoprostane 8-iso-prostaglandin F(2α) (8-iso-PGF(2α)), synthesized in vivo through non-enzymatic free radical catalyzed peroxidation of arachidonic acid, is a widely used biomarker o

Neutralization of LINGO-1 during in vitro differentiation of neural stem cells results in proliferation of immature neurons

Identifying external factors that can be used to control neural stem cells division and their differentiation to neurons, astrocytes and oligodendrocytes is of high scientific and clinical interest. Here we show that the Nogo-66 receptor interacting protein LINGO-1 is a potent regulator of neural stem cell maturation to neurons. LINGO-1 is expressed by cortical neural stem cells from E14 mouse emb