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The silicon isotope composition of Ethmodiscus rex laminated diatom mats from the tropical West Pacific : Implications for silicate cycling during the Last Glacial Maximum

The cause of massive blooms of Ethmodiscus rex laminated diatom mats (LDMs) in the eastern Philippine Sea (EPS) during the Last Glacial Maximum (LGM) remains uncertain. In order to better understand the mechanism of formation of E. rex LDMs from the perspective of dissolved silicon (DSi) utilization, we determined the silicon isotopic composition of single E. rex diatom frustules (δ30SiE. rex) fro

Dissolved silicon isotope dynamics in large river estuaries

Estuarine systems are of key importance for the riverine input of silicon (Si) to the ocean, which is a limiting factor of diatom productivity in coastal areas. This study presents a field dataset of surface dissolved Si isotopic compositions (δ30SiSi(OH)4) obtained in the estuaries of three of the world's largest rivers, the Amazon (ARE), Yangtze (YRE), and Pearl (PRE), which cover different clim

Comparisons on flow characteristics and film cooling performance of cylindrical and sister holes with/without internal coolant crossflow

Simulations and comparisons on the influence of internal coolant crossflow of a novel film cooling hole design, called “sister holes”, and a baseline cylindrical hole were performed with an established turbulence model. The results show that sister holes can provide better film cooling performance than the baseline case at three blowing ratios, and as the blowing ratio increases the sister holes s

Small-scale dosimetry for alpha particle 241Am source cell irradiation and estimation of γ-H2AX foci distribution in prostate cancer cell line PC3

Background: The development of new targeted alpha therapies motivates improving alpha particle dosimetry. For alpha particles, microscopic targets must be considered to estimate dosimetric quantities that can predict the biological response. As double-strand breaks (DSB) on DNA are the main cause of cell death by ionizing radiation, cell nuclei are relevant volumes necessary to consider as targets

Input in study abroad and views from acquisition : Focus on constructs, operationalization and measurement issues: Introduction to the special issue

This article briefly discusses the notion of input in a study abroad perspective, situating it against how input is treated in second language acquisition (SLA) more broadly, with a focus on methodological issues, operationalizations, and measurements. It further introduces three studies that examine input as studied in ‘the real wild’, and two studies that instead focus on ‘the digital wild’.

Experiences of patients with hip fractures after discharge from hospital

Background: To achieve successful rehabilitation after hip fracture and meet patient needs it is important to listen to how individual patients perceive their situation. Purpose: The aim of this study was to explore how patients with hip fractures experience the time after hospitalization. Methods: A qualitative study was performed, data were analyzed using content analysis and included a total of

Entrepreneurial Beliefs of Refugees : It’s Not Where They’re From, But Where They Go

This paper investigates whether structuralist and culturalist approaches to migrant entrepreneurship can explain the early-stage entrepreneurship of recently arrived refugees. Specifically, we empirically test three hypotheses on how refugees’ current geographical location and ethnic origin matter for their entrepreneurial beliefs, which provide the cognitive and affective foundations for entrepre

Transit timing variations of AU Microscopii b and c

Here we report large-amplitude transit timing variations (TTVs) for AU Microcopii b and c as detected in combined TESS (2018, 2020) and CHEOPS (2020, 2021) transit observations. AU Mic is a young planetary system with a debris disk and two transiting warm Neptunes. A TTV on the order of several minutes was previously reported for AU Mic b, which was suggested to be an outcome of mutual perturbatio

Extending depolarized DLS measurements to turbid samples

The application of dynamic light scattering to soft matter systems has strongly profited from advanced approaches such as the so-called modulated 3D cross correlation technique (Mod3D-DLS) that suppress contributions from multiple scattering, and can therefore be used for the characterization of turbid samples. Here we now extend the possibilities of this technique to allow for depolarized light s

Iterative importance sampling with Markov chain Monte Carlo sampling in robust Bayesian analysis

Bayesian inference under a set of priors, called robust Bayesian analysis, allows for estimation of parameters within a model and quantification of epistemic uncertainty in quantities of interest by bounded (or imprecise) probability. Iterative importance sampling can be used to estimate bounds on the quantity of interest by optimizing over the set of priors. A method for iterative importance samp

The atmosphere and architecture of WASP-189 b probed by its CHEOPS phase curve

Context. Gas giants orbiting close to hot and massive early-type stars can reach dayside temperatures that are comparable to those of the coldest stars. These aultra-hot Jupitersahave atmospheres made of ions and atomic species from molecular dissociation and feature strong day-to-night temperature gradients. Photometric observations at different orbital phases provide insights on the planetas atm

Sequence of flexion contracture development in the lower limb : a longitudinal analysis of 1,071 children with cerebral palsy

Background: To prevent severe contractures and their impact on adjacent joints in children with cerebral palsy (CP), it is crucial to treat the reduced range of motion early and to understand the order by which contractures appear. The aim of this study was to determine how a hip–knee or ankle contracture are associated with the time to and sequence of contracture development in adjacent joints. M

Heart age estimated using explainable advanced electrocardiography

Electrocardiographic (ECG) Heart Age conveying cardiovascular risk has been estimated by both Bayesian and artificial intelligence approaches. We hypothesised that explainable measures from the 10-s 12-lead ECG could successfully predict Bayesian 5-min ECG Heart Age. Advanced analysis was performed on ECGs from healthy subjects and patients with cardiovascular risk or proven heart disease. Regress

Shorter reproductive life span is associated with increased cardiovascular risk and total mortality in Swedish women from an observational, population-based study

Objectives: Reproductive history of women is of importance to estimate cardiovascular disease (CVD) risk. One aspect of that history is the reproductive life span (RLS), the period between onset of menarche and menopause. Previous studies have indicated an increased risk associated with shorter RLS, but this has never previously been tested in Scandinavian women. Our aim was to investigate such as

Laser excitation effects in lifetime-based high-speed phosphor thermometry

With high-speed phosphor thermometry becoming more established follows the need for an improved understanding of laser excitation induced measurement errors. With this aim in mind, the impact of kHz laser excitation on the lifetime method was investigated for the phosphors Mg3FGeO6:Mn (MFG) and YVO4:Tm. The results showed that significant measurement errors can occur for both phosphors. The Maximu

Seismic reflectivity, fracturing and stress field data from the FFC-1 exploratory geothermal project in SW Skåne, Sweden

Enhanced geothermal systems (EGS) are a potential heat source in many parts of the world, even in locations where the temperature gradient is relatively low. We present here an integrated study of reflection seismic data, borehole logs and seismicity analysis performed in conjunction with a geothermal exploratory project operated by E.ON in Malmö, Sweden. In 2020, the pre-existing 2.1 km deep FFC-

A moving-boundary model of reactive settling in wastewater treatment. Part 2 : Numerical scheme

A numerical scheme is proposed for the simulation of reactive settling in sequencing batch reactors (SBRs) in wastewater treatment plants. Reactive settling is the process of sedimentation of flocculated particles (biomass; activated sludge) consisting of several material components that react with substrates dissolved in the fluid. An SBR is operated in cycles of consecutive fill, react, settle,

Child labour and health hazards: chemical exposure and occupational injuries in Nicaraguan children working in a waste disposal site

Omkring 600 barn och tonåringar arbetar på Managuas stora soptipp, denbstörsta i Nicaragua. De samlar och sorterar avfall på den öppna tippen, sombtäcker ett 7 km2 stort område i stadens utkant vid stranden av Managuasjön. Sådant arbete, som förekommer i många stora städer i utvecklingsländer, ansesbvara ett av de mest riskfyllda typerna av barnarbete som finns. Ändå är kunskapen om sådant arbete About 600 children and teenagers work at Managua's landfill, the largest in Nicaragua. They collect and sort waste at the open dump, which covers an area of 7 km2 on the outskirts of the city on the shores of Lake Managua. Such work, which occurs in many large cities in developing countries, is considered to be one of the riskiest types of child labor that exists. Nevertheless, knowledge of such w

Thrombotic risk determined by rare and common SERPINA1 variants in a population-based cohort study

Background: Severe alpha-1-antitrypsin deficiency (AATD), phenotype PiZZ, was associated with venous thromboembolism (VTE) in a case-control study. Objectives: This study aimed to determine the genetic variation in the SERPINA1 gene and a possible thrombotic risk of these variants in a population-based cohort study. Patients/Methods: The coding sequence of SERPINA1 was analyzed for the Z (rs289294

The shortest even cycle problem is tractable

Given a directed graph as input, we show how to efficiently find a shortest (directed, simple) cycle on an even number of vertices. As far as we know, no polynomial-time algorithm was previously known for this problem. In fact, finding any even cycle in a directed graph in polynomial time was open for more than two decades until Robertson, Seymour, and Thomas (Ann. of Math. (2) 1999) and, independ