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Review of Jon A. Shields & Joshua M. Dunn, Passing on the Right: Conservative Professors in the Progressive University

Photoplethysmogram modeling during paroxysmal atrial fibrillation : Detector evaluation

A phenomenological model for simulating photoplethys-mogram (PPG) during paroxysmal atrial fibrillation (AF) is proposed. A PPG pulse is modeled by combining a lognormal and two Gaussian waveforms. Continuous PPG signals are produced by placing and connecting individual pulses according to the RR interval pattern extracted from annotated ECG signals. This paper presents a practical application of

Measuring Frailty among Older People : Further Evaluation of the Brody Frailty Index

BACKGROUND AND OBJECTIVE: The study aimed to evaluate the predictive validity of the Brody self-report frailty index among older people. Design, setting and measurements: A longitudinal cohort study (2-years) conducted in Sweden, which included 1141 respondents, aged 65-103 years. Data were collected during 2011-2013 through a postal questionnaire with questions about demographic data, living cond

After-School Care and Parents' Labor Supply

Does the provision of after-school care promote maternal employment and thus help to foster gender equality in labor supply? We address this question by exploiting variation in cantonal (state) regulations of after-school care provision in Switzerland. To establish exogeneity of cantonal regulations with respect to employment opportunities and preferences of the population, we restrict our analysi

Sustained glucagon-like peptide 1 expression from encapsulated transduced cells to treat obese diabetic rats

Obesity and type 2 diabetes (T2D) are two prevalent chronic diseases that have become a major public health concern in industrialized countries. T2D is characterized by hyperglycemia and islet beta cell dysfunction. Glucagon-like peptide 1 (GLP-1) promotes β cell proliferation and neogenesis and has a potent insulinotropic effect. Leptin receptor deficient male rats are obese and diabetic and prov

Genetics and developmental biology of cooperation

Despite essential progress towards understanding the evolution of cooperative behaviour, we still lack detailed knowledge about its underlying molecular mechanisms, genetic basis, evolutionary dynamics and ontogeny. An international workshop “Genetics and Development of Cooperation,” organized by the University of Bern (Switzerland), aimed at discussing the current progress in this research field

Ethanol Solvation in Water Studied on a Molecular Scale by Photoelectron Spectroscopy

Because of the amphiphilic properties of alcohols, hydrophobic hydration is important in the alcohol-water system. In the present paper we employ X-ray photoelectron spectroscopy (XPS) to investigate the bulk and surface molecular structure of ethanol-water mixtures from 0.2 to 95 mol %. The observed XPS binding energy splitting between the methyl C 1s and hydroxymethyl C 1s groups (BES-[CH3-CH2OH

En berättelse om organisering

En berättelse om organisering blandar fiktion med organisationsteorins grunder. Boken drivs framåt av vad som händer på det nystartade modeföretaget Mess. Genom skildringen av Mess och människorna i och runt omkring företaget ser vi framgångar, konflikter och utmaningar i organisationsteorins ljus.Mötet mellan den fiktiva berättelsen och de teoretiska fördjupningarna ger grundläggande förståelse f

Mitigation of Alien Crosstalk for Downstream DSL Impaired by Multiple Interferers

Alien crosstalk is one of the major impairments for copper-based transmissions. This letter outlines a method for mitigating alien crosstalk for DSL downstream transmissions impaired by multiple interference sources. The method requires a reference channel, and includes a post processing stage in which induced correlation is applied to prepare the interference at the target channel to be reasonabl

Recognition of glutamic acid decarboxylase (GAD) by autoantibodies from different GAD antibody-positive phenotypes

Autoantibodies against the smaller isoform of glutamic acid decarboxylase (GAD) are markers for Type 1 diabetes. GAD65 autoantibody (GAD65Ab)-positive individuals in the general population are, however, mostly at low risk of developing Type 1 diabetes, suggesting that GAD65Ab phenotypes may be associated with different underlying pathogenic processes. The aim of this study was to test the hypothes

An extension of digital volume correlation for multimodality image registration

The question of registering two images (or image volumes) acquired with different modalities, and thus exhibiting different contrast, at different positions is addressed based on an extension of global digital image (or volume) correlation. A specific comparison metric is introduced allowing the signature of the different phases to be related. A first solution consists of a Gaussian mixture to des

Prolonged survival and improved glycemia in BioBreeding diabetic rats after early sustained exposure to glucagon-like peptide

Background: Type 1 diabetes (T1D) in both humans and BioBreeding (BB) rats is an autoimmune disease that results in complete destruction of islets and insulin dependency for life. Glucagon-like peptide 1 (GLP-1) promotes β cell proliferation and neogenesis and has a potent insulinotropic effect. We hypothesized that the expression of GLP-1 before disease onset would increase islet mass, delay diab

Guidelines and recommendations for laboratory analysis in the diagnosis and management of diabetes mellitus

BACKGROUND - Multiple laboratory tests are used to diagnose and manage patients with diabetes mellitus. The quality of the scientific evidence supporting the use of these tests varies substantially. APPROACH - An expert committee compiled evidence-based recommendations for the use of laboratory testing for patients with diabetes. A newsystemwas developed to grade the overall quality of the evidenc

Bee diversity in crop fields is influenced by remotely-sensed nesting resources in surrounding permanent grasslands

Landscape heterogeneity is an important driver of biodiversity in agroecosystems. However, the functional heterogeneity of agricultural landscapes, taking into account the different resources that habitat patches can provide to species, has rarely been studied. In this study, we explored the effect of landscape-scale nest availability provided by permanent grasslands on wild bee communities. Wild

Is there an age limit for abdominal aortic aneurysm repair?

INTRODUCTION: There is an increasing number of elderly in society and some of them may have an abdominal aortic aneurysm (AAA). The prevalence of AAA in octo-And nonagenarians indicates that this number could be substantial. The question is: is there an age limit for repair? This complex question incorporates ethical, political, economic and medical aspects. To answer part of this question a revie

Type 1diabetes in parents and risk of attention deficit/hyperactivity disorder in offspring : A population-based study in Sweden

OBJECTIVE To explore whether a family history of type 1 diabetes (T1D) is associated with an increased incidence of attention deficit/hyperactivity disorder (ADHD) in offspring. RESEARCH DESIGN AND METHODS Individuals with T1D were identified from the nationwide Swedish National Hospital Discharge Register and Swedish Outpatient Register in Sweden and were linked to the SwedishMulti-Generation Reg

Dynamic Channel Model with Overhead Line Poles for High-Speed Railway Communications

In order to develop reliable communications links for high speed railway (HSR) systems, accurate models for the propagation channel are required. The radio channel properties in HSR scenarios are different from those in cellular scenarios not only due to the high velocity, but also due to the special construction elements and the type of surroundings along the train lines. This paper focuses on th