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Kliniska kriterier bästa stöd för diagnosen lätt till måttlig artros. Symtomen, inte röntgenundersökningen, styr valet av behandling

No generally accepted definition of osteoarthritis exists. Traditionally, the diagnosis is obtained by radiographic examination but different definitions are used for different purposes. Since no causal treatment exists, treatment is aiming at reducing symptoms and improving function. The correlation between radiographic features of osteoarthritis and symptoms is poor. Thus, it is recommended that

Keto- and acetyl-keto-boswellic acids inhibit proliferation and induce apoptosis in Hep G2 cells via a caspase-8 dependent pathway.

Boswellic acids are the compounds isolated from the gum resin of Boswellia serrata and have been used for the treatment of inflammatory diseases for many years in the countries of the east. Recently, a few studies showed that the acids may have anti-cancer effect on leukemia and brain tumours. We investigated the apoptotic and anti-proliferative effects of two types of boswellic acids, keto-beta-b

Dependence of Curie temperature on the thickness of epitaxial (Ga,Mn)As film

We present the magnetotransport properties of very thin (5-15 nm) single (Ga,Mn)As layers grown by low-temperature molecular beam epitaxy. A lower (Ga,Mn)As thickness limit of 5 nm for the ferromagnetic phase and the dependence of the Curie temperature on (Ga,Mn)As thickness are determined from electrical-transport measurements. The Curie temperature is determined to be 97 K for the thinnest ferro

A method to simultaneously determine sorption isotherms and sorption enthalpies with a double twin microcalorimeter

Sorption of vapors of water, ethanol, and other liquids on solids like pharmaceuticals, textiles and food stuffs are of both practical and theoretical importance. In this article we present a technique to simultaneously measure sorption isotherms and sorption enthalpies. The sample is contained in one end of a sorption vessel. In the other end a vaporizable liquid is introduced to start the measur

Hydrogenation of Benzene to Cyclohexene on an Unsupported Ruthenium Catalyst: Effects of Poisons

The influence of poisoning of ruthenium catalysing the selective hydrogenation of benzene to cyclohexene has been studied. Both the yield of cyclohexene and the rate of hydrogenation are greatly affected by the degree of poisoning (e.g. FeSO4, FeCl3, TiCl3 and oxygen), and may also be optimised. A reproducible catalyst has been prepared by precipitating the catalyst precursor, as the hydroxide, in

Action spectra for conversions of phycochrome c from Nostoc-muscorum

The reversibly photochromic pigment, phycochrome c, was extracted from the blue-green alga Nostoc muscorum strain A. Action spectra were determined for in vitro conversions of the pigment from the short wavelength to the long wavelength form and vice versa. The action peak for the absorbance decrease at 650 nm is at 630 nm. During this decrease there is only a slight increase of the absorbance in

Approximation Algorithms for Geometric Networks

Popular Abstract in Swedish Det huvudsakliga bidraget i denna avhandling är approximationsalgoritmer för flera problem inom beräkningsgeometri. Den underliggande strukturen för de flesta problemen är ett geometriskt nätverk. Ett geometriskt nätverk är, i sin mest abstrakta form, en mängd noder parvis kopplade med en kant, sådan att vikten på denna kant är lika med det Euklidiska (geometriska) avstThe main contribution of this thesis is approximation algorithms for several computational geometry problems. The underlying structure for most of the problems studied is a geometric network. A geometric network is, in its abstract form, a set of vertices, pairwise connected with an edge, such that the weight of this connecting edge is the Euclidean distance between the pair of points connected. S

Ecosystem subsidies: Terrestrial support of aquatic food webs from C-13 addition to contrasting lakes

Whole-lake additions of dissolved inorganic C-13 were used to measure allochthony (the terrestrial contribution of organic carbon to aquatic consumers) in two unproductive lakes (Paul and Peter Lakes in 2001), a nutrient-enriched lake (Peter Lake in 2002), and a dystrophic lake (Tuesday Lake in 2002). Three kinds of dynamic models were used to estimate allochthony: a process-rich, dual-isotope flo

How the Co-C bond is cleaved in coenzyme B-12 enzymes: A theoretical study

The homolytic cleavage of the organometallic Co-C bond in vitamin B-12-dependent enzymes is accelerated by a factor of similar to 10(12) in the protein compared to that of the isolated cofactor in aqueous solution. To understand this much debated effect, we have studied the Co-C bond cleavage in the enzyme glutamate mutase with combined quantum and molecular mechanics methods. We show that the cal

The upper limit of flammability of hydrogen in air, oxygen, and oxygen-inert mixtures at elevated pressures

The upper limit of flammability of hydrogen in air, oxygen, oxygen-helium, oxygen-neon, oxygen-argon and oxygen-carbon dioxide mixtures was measured at room temperature and pressures between 0.97 and 29 atm in two cylindrical bombs with volumes of 1.5 and 5.2 liters. The limit in ternary mixtures was determined in 20%, 40%, 60% and 80% helium, 20% neon and argon and 10% carbon dioxide concentratio

Test-retest reliability of knee kinesthesia in healthy adults

Background Sensory information from mechanoreceptors in the skin, muscles, tendons, and joint structures plays an important role in joint stability. A joint injury can lead to disruption of the sensory system, which can be measured by proprioceptive acuity. When evaluating proprioception, assessment tools need to be reliable. The aim of this study was to assess the test-retest reliability of a de

Prevalence and clinical correlations of antibodies against six beta 2-glycoprotein-I-related peptides in the antiphospholipid syndrome

Two-hundred ninety five patients with the antiphospholipid syndrome (APS) were studied for the presence of antibodies against six anti-beta2GPI-related peptides Abs. The prevalence of a wide spectrum of clinical and laboratory parameters of APS was evaluated in all patients, and correlated with the presence of each anti-beta2GPI peptide antibody. The rates of the various antipeptides Abs ranged fr

Some novel aspects of DNA physical and chemical gels

DNA chemical and physical networks have been investigated with respect to their stability and swelling, and rheological properties. Chemical networks were prepared by cross-linking DNA with ethylene glycol diglycidyl ether (EGDE), and physical networks by association with cationic polymers. Both types of gels display strong elastic properties and have a shear thinning behaviour. Addition of cation