Background: Criminal offending is strongly transmitted across generations. Aims: To clarify the contribution of rearing environment to crossgenerational transmission of crime. Method: Using Swedish national registries, we identified 1176 fullsibling and 3085 half-sibling sets from high-risk families where at least one sibling was adopted and the other raised by the biological parents. Results: Ris

Limited data are available about the role of the serotonin 2B (5-HT2B) receptor in the function of human islets. This study aimed to test whether the 5-HT2B receptor contributes to glucose, insulin, and glucagon homeostasis in humans, utilizing a hereditary loss-of-function gene mutation in the receptor, which causes a 50% reduction in the production of the receptor protein in heterozygotes. This

Cone-rod degeneration (CRD) belongs to the disease spectrum of retinal degenerations, a group of hereditary disorders characterized by an extreme clinical and genetic heterogeneity. It mainly differentiates from other retinal dystrophies, and in particular from the more frequent disease retinitis pigmentosa, because cone photoreceptors degenerate at a higher rate than rod photoreceptors, causing s

N-terminal pro-B-type natriuretic (NT-proBNP) is expressed in the heart and brain, and serum levels are elevated in acute heart and brain diseases. We aimed to assess the possible association between serum levels and neurological outcome and death in comatose patients resuscitated from out-of-hospital cardiac arrest (OHCA). Of the 939 comatose OHCA patients enrolled and randomized in the Targeted

This paper discusses some of the main issues of efficient analysis of electrically very large endfire arrays, and further proposes approaches for developing flexible simulation tools for this particular purpose. Some initial results supporting the endfire array design issue are presented, as well as some preliminary examples of implemented compression- and acceleration methods.

Physical bounds for antennas above ground planes are calculated by optimizing the antenna current. The bounds are compared with antennas modeled as fragmented patches and optimized using genetic algorithms. Monopole structures over ground planes are modeled with image theory and optimized. The monopole over ground plane structure simplifies experimental verification of the bounds.

A windowless silicon (Si) diode (4 mm2) was evaluated as alpha particle detector and spectrometer for field measurements. It was irradiated with alpha particles from a 241Am (2.3 kBq) and a 210Po (9 kBq) source at source-detector distances (SDD) of 0.5, 1.0 and 1.8 cm. The energy resolution in terms of full width at half maximum was 281, 148 and 113 keV for SDD of 0.5, 1.0 and 1.8 cm, respectively

Background: Symptoms have been identified as a core outcome domain for atopic eczema (AE) trials. Various instruments exist to measure symptoms in AE, but they vary in quality and there is a lack of standardization between clinical trials. Our objective was to systematically evaluate the quality of the evidence on the measurement properties of AE symptom instruments, thereby informing consensus di

Introduction: Increased exhaled nitric oxide (NO) levels in asthma are suggested to be through inducible NO synthase (iNOS). The aim of this study was to investigate the expression of iNOS in bronchoalveolar lavage (BAL) cells and tissue from central and peripheral airways and compare it with the exhaled bronchial and alveolar NO levels in patients with asthma vs a control group. Methods: Thirty-t

BACKGROUND: Transforming growth factor-β1 (TGF-β1) is a potent regulator of cell growth and differentiation. TGF-β1 has been shown to be a key player in tissue remodeling processes in a number of disease states by inducing expression of extracellular matrix proteins. In this study a quantitative proteomic analysis was undertaken to investigate if TGF-β1 contributes to tissue remodeling by mediatin

Handel och resande är en förutsättning för internationellt utbyte av såväl varor och människor som kultur och innovationer. Handeln och resandet går tillbaka till historiens gryning men har under de senaste århundradena blivit en allt viktigare del i den ekonomiska utvecklingen. Globaliseringen har till följd av tilltagande ekonomiskoch politisk integration drivit på utvecklingen av resandet och s

This position document has been developed by the Dysphagia Working Group, a committee of members from the European Society for Swallowing Disorders and the European Union Geriatric Medicine Society, and invited experts. It consists of 12 sections that cover all aspects of clinical management of oropharyngeal dysphagia (OD) related to geriatric medicine and discusses prevalence, quality of life, an

BACKGROUND CONTEXT: Proper patient selection is of outmost importance in surgical treatment of degenerative disc disease (DDD) with chronic low back pain (CLBP). Among other factors gender was previously found to influence lumbar fusion surgery outcome.PURPOSE: This study investigates whether gender affects clinical outcome after lumbar fusion.STUDY DESIGN: National registry cohort study PATIENT S

INTRODUCTION: Information about the education, training and future employment prospects of Icelandic surgeons has not been available.MATERIALS AND METHODS: The study included all Icelandic surgeons, in all subspecialties, educated at the Faculty of Medicine at the University of Iceland. Information on specialty training, higher academic degrees and in which country these were obtained was collecte

The regulations on the emissions from combustion devices are getting more and more strict for environmental and human health reasons. Modern combustion research faces two major challenges; reduction of the pollutants, such as CO, NOx and unburnt hydro- carbons and increase of the combustion efficiency. Current trend for stationary power generation is to use lean premixed and/or pre-vaporized combu

This thesis explores office paper as a medium between 1920 and 1960 in Sweden. During this period, paper was muchdebated due to the number of standards that were implemented. These standardstransformed paper, making it a modern medium in many different ways. The aim ofthe present thesis is to analyze how office paper was reshaped to solveproblems regarding production, reproduction, circulation and