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Pacemaker Implants and Their Influence on the Daily Life of Patients with Dementia with Lewy Bodies : A Qualitative Case Study

INTRODUCTION: Dementia with Lewy bodies (DLB) is an incurable form of dementia associated with detriments to the daily life of patients and carers from their family. Symptoms of orthostatic hypotension, syncope, and falls are supportive of DLB diagnosis. These symptoms may also be present among people with sick sinus syndrome (SSS), and subsequent pacemaker treatment to manage bradyarrhythmia is a

Phase Correction and Noise-to-Noise Denoising of Diffusion Magnetic Resonance Images Using Neural Networks

Diffusion magnetic resonance imaging (dMRI) is an important technique used in neuroimaging. It features a relatively low signal-to-noise ratio (SNR) which poses a challenge, especially at stronger diffusion weighting. A common solution to the resulting poor precision is to average signal from multiple identical measurements. Indeed, averaging the magnitude signal is sufficient if the noise is samp

Putting Faces to Names : Printed Portraits in Late Eighteenth-Century Stockholm

In the eighteenth century, the portrait genre, previously restricted to royalty and nobility, became available to users from a broader social spectrum. All over Europe, physicians, scholars, writers, merchants, and proprietors had their portraits painted to mark their standing in society. However, not these grand paintings but their printed versions made the sitters known to the broader public. Bu

Oxygen saturation mapping during reconstructive surgery of human forehead flaps with hyperspectral imaging and spectral unmixing

BACKGROUND: Optical spectroscopy is commonly used clinically to monitor oxygen saturation in tissue. The most commonly employed technique is pulse oximetry, which provides a point measurement of the arterial oxygen saturation and is commonly used for monitoring systemic hemodynamics, e.g. during anesthesia. Hyperspectral imaging (HSI) is an emerging technology that enables spatially resolved mappi

A novel nonsense variant in RHAG underlies a Nordic Rhnull phenotype.

BACKGROUND AND OBJECTIVES: The extremely rare Rh null phenotype is characterized by the absence of all Rh antigens on erythrocytes. It is divided into the regulator and amorph types based on the underlying genetic background. The more common regulator type depends on critical variants silencing RHAG, which encodes RhAG glycoprotein, necessary for RhD/RhCE expression. Rh null cells have altered exp

Babesia divergens Shows Equal Predilection for Human ABO Blood Types in an In Vitro Erythrocyte Preference Assay.

Babesia is spread to humans via ticks or blood transfusions. Severity of Plasmodium falciparum malaria is strongly correlated to the ABO blood group of the patient. Babesia divergens is an intraerythrocytic parasite with many similarities to malaria, but the impact of ABO on the susceptibility to and progression of the infection in humans is unknown. We have now cultured B. divergens in human

The LW blood group system : not just "tagging along" with D

This update of the Landsteiner-Wiener (LW) blood group system (Grandstaff Moulds MK. The LW blood group system: a review. Immunohematology 2011;27:136-42. Storry JR. Review: the LW blood group system. Immunohematology 1992;8:87-93) reports new information on the distribution of genetic variants in ICAM4 and reviews the complex serologic identification of the high-prevalence LWEM antigen. The role

Sag-rad : A Method for Single-Cell Population Genomics of Unicellular Eukaryotes

Sequencing of reduced representation libraries enables genotyping of many individuals for population genomic studies. However, high amounts of DNA are required, and the method cannot be applied directly on single cells, preventing its use on most microbes. We developed and implemented the analysis of single amplified genomes followed by restriction-site-associated DNA sequencing to bypass labor-in

Auditory vs. audiovisual prominence ratings of speech involving spontaneously produced head movements

Visual information can be integrated in prominence perception, but most available evidence stems from controlled experimental settings, often involving synthetic stimuli. The present study provides evidence from spontaneously produced head gestures that occurred in Swedish television news readings. Sixteen short clips (containing 218 words in total) were rated for word prominence by 85 adult volun

Development strategies in a context of world system disorder

The world has been through several major crises since the beginning of the new millennium and the old-world order, with the US as hegemonic power, is challenged by the rise of China. There has been a reversal of, as well as directional change in, the globalization trend. A weakening of international collaboration is taking place against a backdrop of global challenges such as climate change, digit

The importance of the setting during sedation for intrathecal chemotherapy in pediatric oncology care : A case study

Increasing survival rates for childhood cancer have brought attention to the high level of burden of cancer and its treatment. Improving supportive care for children throughout their cancer trajectory is thus important and could reduce the difficulties related to treatment, including time-consuming treatments and the waiting time associated with treatment procedures. The aim of this study is to de

Creating a shielding place for children with leukaemia during sedation for intrathecal chemotherapy : A grounded theory study

Purpose: Childhood cancer invades the child's daily life and has a strong influence on their living conditions and lifestyle. The treatment is an unpleasant experience and the children often perceive the treatment as worse than the actual disease. The aim of the present study was thus to explore the process of how healthcare professionals improved care for children undergoing sedation for intrathe

Participation in paediatric perioperative care : ‘what it means for parents’

Aims and objectives: To explore what it means for parents to participate in their children's paediatric perioperative care. Background: Allowing parents to participate in paediatric perioperative care can make a major difference for children in terms of their well-being, a decreased need for painkillers, fewer sleeping disorders and a more positive experience for both parties. The nurse anaestheti

The perspective of children on factors influencing their participation in perioperative care

Aims and objectives: To describe the experiences of participation in perioperative care of 8- to 11-year-old children. Background: All children have the right to participate in decisions that affect them and have the right to express their views in all matters that concern them. Allowing children to be involved in their perioperative care can make a major difference in terms of their well-being by

The governmentalisation of risk in liberal democracies : Four processes both making and breaking the governing of risk on the societal level

Numerous risks threaten modern society. Some are new, while others have existed since the beginning of time, but none have been governed on a societal level since their inception. Despite the abundance of literature addressing the governance of various risks, the processes by which they become governable in the first place have gotten little attention. As a result, this paper aims to improve our k

Reconceptualizing Cross-Cutting Political Expression on Social Media : A Case Study of Facebook Comments During the 2016 Brexit Referendum

Political communication research has long sought to understand the effects of cross-cutting exposure on political participation. Here, we argue for a paradigm shift that acknowledges the agency of citizens as producers of cross-cutting expression on social media. We define cross-cutting expression as political communication through speech or behavior within a counter-attitudinal space. After expli