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A series of experimental measurements on a prototype premixed swirl burner with complex geometry were carried out using CH2O/OH-PLIF. FGM method(SFGM)taking account of strain rate was developed to study two modes of premixed swirl flame, one stabilized and the other close to blown-off flame under the same Reynolds number(Re=10000). The SFGM model in this work is related to a reaction factor, which
International severe asthma registry (ISAR) : protocol for a global registry
BACKGROUND: Severe asthma exerts a disproportionately heavy burden on patients and health care. Due to the heterogeneity of the severe asthma population, many patients need to be evaluated to understand the clinical features and outcomes of severe asthma in order to facilitate personalised and targeted care. The International Severe Asthma Registry (ISAR) is a multi-country registry project initia
A Functional ClpXP Protease is Required for Induction of the Accessory Toxin Genes, tst, sed, and sec
Staphylococcal toxic shock syndrome is a potentially lethal illness attributed to superantigens produced by Staphylococcus aureus, in particular toxic shock syndrome toxin 1 (TSST-1), but staphylococcal enterotoxins (SEs) are also implicated. The genes encoding these important toxins are carried on mobile genetic elements, and the regulatory networks controlling expression of these toxins remain r
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Till hundraårsminnet av ett studentmöte i Göteborg
Disentangling production and climate signals from high-resolution Beryllium records: implications for solar and geomagnetic reconstructions
The sun is the most important energy source for the Earth’s climate system, however, influences of solar variations on climate are not fully understood. Studying past solar activity can improve our understanding of what role the sun plays in Earth’s climate. Cosmogenic radionuclides, such as 10Be in ice cores, are powerful tools to reconstruct past solar activity before the period of direct telesc
Cortico-Striatal Oscillations Are Correlated to Motor Activity Levels in Both Physiological and Parkinsonian Conditions
Oscillatory neural activity in the cortico-basal ganglia-thalamocortical (CBGTC) loop is associated with the motor state of a subject, but also with the availability of modulatory neurotransmitters. For example, increased low-frequency oscillations in Parkinson’s disease (PD) are related to decreased levels of dopamine and have been proposed as biomarkers to adapt and optimize therapeutic interven
Comparative effectiveness of abatacept, rituximab, tocilizumab and TNFi biologics in RA : Results from the nationwide Swedish register
Objectives: Current guidelines rank abatacept, rituximab, tocilizumab and TNF-inhibitors (TNFi) as having equal effectiveness for the treatment of RA, at least as second line therapies. These recommendations are mainly based on meta-analysis of randomized controlled trials, with few direct drug-drug comparisons. Our objective was to compare the real-world absolute and relative effectiveness among
Coarse-Grained Modelling of Protein Adsorption
The adsorption of proteins is a very common phenomenon, happening almost always when a protein solution comes into contact with a solid. However, it is far from always clear what the results of adsorption will be in terms of adsorbed amount, protein orientation, and protein conformation. In this work, the adsorption of two proteins – histatin 5 and fibrinogen – has been studied using coarse-graineThe adsorption of proteins is a very common phenomenon, happening almost always when a protein solution comes into contact with a solid. However, it is far from always clear what the results of adsorption will be in terms of adsorbed amount, protein orientation, and protein conformation. In this work, the adsorption of two proteins – histatin 5 and fibrinogen – has been studied using coarse-graine
Oligodendroglial (dys)function in alpha-synucleinopathies
Komplexiteten hos a-synukleinopatier, som inkluderar multipel systematrofi (MSA) och Parkinsons sjukdom (PS), är inte helt klarlagd. Det är känt att patologisk ansamling av a-synuclein (a-syn) till fiberlika proteinaggregat är ett cellulärt kännetecken för dessa sjukdomar. a-Syn-positiva aggregat förekommer i nervceller i PS och Lewy body demens (LBD) och i oligodendrocyter i MSA. Mycket forskningThe complexity of a-synucleinopathies, which include multiple system atrophy (MSA) and Parkinson’s disease (PD), is not entirely understood. It is known that pathological accumulation of a-synuclein (a-syn) into proteinaceous aggregates is a cellular hallmark of these diseases. a-Syn positive aggregates appear in neurons in PD and dementia with Lewy bodies (DLB), and in oligodendrocytes in MSA. Mu
Six Policy Ideas for Coping with the COVID-19 Pandemic
This white paper contains six policy ideas that may help countries in coping with theCOVID-19 pandemic. The paper focuses on policies that can slow down the spread of the disease, better protect high-risk groups and leverage that a large part of the labor force is idle. For each policy idea, we describe the problem it is meant to solve, what may be leveraged to solve it, and a brief analysis of beThis white paper contains six policy ideas that may help countries in coping with theCOVID-19 pandemic. The paper focuses on policies that can slow down the spread of the disease, better protect high-risk groups and leverage that a large part of the labor force is idle. For each policy idea, we describe the problem it is meant to solve, what may be leveraged to solve it, and a brief analysis of be
Optimal Design of a High Voltage High Frequency Transformer and Power Drive System for Long Pulse Modulators
The stacked multi-level (SML) klystron modulator topology has been suggested as an alternative to conventional pulse transformer based topologies in an attempt to improve output pulse performance and reduce system size for long pulse applications. In this topology, a power converter chain including a high frequency transformer generates the output pulse in a pulse modulation/demodulation scheme, e
Non-invasive Prediction of Cardiac Resynchronization Therapy. Focus on the role of atrial fibrillation, device-diagnostics and ECG-based risk markers
UV exposure : A novel processing method to fabricate nanowire solar cells
We demonstrate a novel and rapid method for nanowire (NW) solar cell processing. NW arrays were embedded in photoresist. The strong absorption of light in the NWs leads to self-limited exposure of the resist, which enables selective removal of the exposed part of the resist, opening up for the tips of the NWs and further processing. The UV-exposure technology allows a fast and low-cost process com
Evaluation of different macular degenerations. Function, morphology and clinical outcomes.
Nanoprobe-Enabled Electron Beam Induced Current Measurements on III-V Nanowire-Based Solar Cells
Electron beam induced current (EBIC) is a well-established tool to, among others, locate and analyze p-n junctions, Schottky contacts or heterostructures in planar devices and is now becoming essential to study and optimize devices at the nanoscale, like III-V nanowire (NW) based solar cells. Here, we report on EBIC measurements on III-V single NW solar cells as well as on fully processed NW devic
Tomographic reconstruction with a generative adversarial network
This paper presents a deep learning algorithm for tomographic reconstruction (GANrec). The algorithm uses a generative adversarial network (GAN) to solve the inverse of the Radon transform directly. It works for independent sinograms without additional training steps. The GAN has been developed to fit the input sinogram with the model sinogram generated from the predicted reconstruction. Good qual
Organizational Hindrances to the Retention of Older Healthcare Workers
The Swedish healthcare sector is currently experiencing recruitment difficulties combined with increasing demand for healthcare services. This study accordingly seeks knowledge of the obstacles to and opportunities for retaining older employees in the Swedish healthcare sector. Results of interviews with line managers and human resource (HR) partners indicate that the informants have positive atti
Photoinduced phase segregation and degradation of perovskites revealed by x-ray photoelectron spectroscopy
Pb-based perovskite absorbers with organic (i.e., CH3NH3+) and inorganic (i.e., Cs+) cations and a halide composition of 75% Br and 25% I are investigated with x-ray photoelectron spectroscopy while submitted to environmental stress factors to study their stability. Changes in chemical properties of the absorbers were monitored in ultra-high vacuum and under simulated solar, as well as, x-ray irra
