Objective: to describe the trends of self-reported past consumption of alcoholic beverages and ethanol intake from 1950. to 1995 within the European Prospective Investigation into Cancer and Nutrition (EPIC). Design: Data-on consumption of beer/cider, wine and liqueur/spirits were obtained age 20, 30 and 40 years to calculate average consumption and retrospectively at ethanol intake for the time p

Allergic rhinitis is a predisposing factor for developing clinical asthma. Moreover, allergic rhinitis is often associated with bronchial hyperresponsiveness (BHR). We hypothesise that patients with asthma have more small airway involvement than those with allergic rhinitis and BHR alone. The aim of this study was to assess peripheral and proximal NO concentration in rhinitic subjects, and to corr

We report the solution structure of human prolactin determined by NMR spectroscopy. Our result is a significant improvement over a previous structure in terms of number and distribution of distance restraints, regularity of secondary structure, and potential energy. More significantly, the structure is sufficiently different that it leads to different conclusions regarding the mechanism of recepto

Popular Abstract in Swedish Som en följd av Brömsebrofreden mellan Sverige och Danmark 1645 övergick östersjöns största ö, Gotland, i svensk ägo. Mellan två riken är en undersökning av hur övergången upplevdes "underifrån". Hur den påverkade de gotländska böndernas vardagspolitiska handlingsmönster och föreställningsvärldar. Undersökningens huvudresultat är att den statliga integrationspolitiken lUnder the peace treaty of Brömsebro in 1645 the largest island of the Baltic Sea, Gotland, became a part of the Swedish Kingdom. Until then it had been under Danish control, and since the late fifteenth century the Danish authorities had pursued the economic, judicial, administra-tive and ecclesiastical incorporation of the island. This policy was continued, and its scope wide-ned, by the Swedish

The present report concerns a performance-based fire safety analysis and design of a high-rise building. The resulting fire safety recommendations are compared with those specified by acceptable solutions in terms of the earlier prescriptive building code. The respective risk to life resulting from the analyses is compared and discussed. The benefit and need of using a risk based verification meth

A new method for rapid determination of ethanol was developed, using alcohol dehydrogenase as recognition element for the SIRE (R) (sensors based on injection of the recognition element) Biosensor, which is an amperometric biosensor. The method was simple, fast, accurate, specific and cost-effective. The recognition element solution used was stable at least for 24h in room temperature, and at leas

The CST3 Thr25 allele of CST3, which encodes cystatin C, leads to reduced cystatin C secretion and conveys susceptibility to Alzheimer's disease. Here we show that overexpression of human cystatin C in brains of APP-transgenic mice reduces cerebral amyloid-beta deposition and that cystatin C binds amyloid-beta and inhibits its fibril formation. Our results suggest that cystatin C concentrations mo

Four qualitative methods for the detection of beta-lactamase production in Staphylococcus and Micrococcus species were evaluated and compared with a quantitative macroiodometric reference method. The disc diffusion test with penicillin G and the cloverleaf method could not separate beta-lactamase-positive from beta-lactamase-negative strains. Two applications of the chromogenic cephalosporin test,

Salt linkages, electrostatic effects, and modified water structure are important for the properties of gluten, wheat flour dough, and baking (Belitz et al 1986). These effects have been studied at various levels of salt concentration, pH, and ion strength (Doguchi and Hlynka 1967; Salovaara 1982; Kinsella and Hale 1984; Holmes and Hoseney 1987 Preston 1989; He et al 1992). Sodium chloride usually

The purpose of this report is to design a thickness controller fo a hot rolling mill. The thickness control problem is difficult and small improvements make large savings possible. It is therefore relevant to use advanced control strategiesfor controlling the plate thickness. In the report a short introduction to the thickness control problem, and a description ofhow thickness control is done toda

Many concrete dams, and other concrete structures within the hydropower industry are old and in a more or less severe state of degradation. Leaching is, together with freeze-thaw, the most common degradation problem in Swedish hydraulic concrete structures. This report contains a literature survey of concrete leaching, and presents the results of an experimental determination of leaching.

A near-natural coastal dune system in NW Jutland, Denmark was investigated. The area contains a gradient in natural soil mobility with the highest values in dynamic white dunes dominated by Ammophila arenaria, and low mobility in fixed decalcified dune heath with Empetrum nigrum and Calluna vulgaris. A total of 267 plots was investigated and presence of mosses and rooted vascular plants recorded.

The energy transfer within a series of Zn-porphyrin appended dendrimers was studied by means of time-resolved fluorescence anisotropy. We show that the energy transfer process between the Zn-porphyrin units in the dendrimers is limited to a maximum of four porphyrin units. At 200 K, the energy transfer process takes place on a 100-ps time scale, and can be modeled by Forster theory. Our results at

Aims. The isotope composition of samarium provides a previously unexploited means of determining the r- versus s-process content of e. g. metal-poor stars. The seven stable isotopes of samarium can be divided into two groups, where in one group the r- process is the dominant production mechanism, while for the second group it is the s-process that is dominant. The center-of-gravity for spectral li

Objective:To determine whether the combined intervention of 50 000 IU vitamin A administered together with Bacille Calmette-Guerin (BCG) vaccination at birth was associated with adverse events, in particular bulging fontanels and adverse reactions to BCG.Subjects/Methods:From an ongoing trial, 2145 infants randomized to 50 000 IU vitamin A or placebo with BCG vaccination were recruited. Adverse ev