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A prospective study of positron emission tomography for evaluation of neck node response 6 weeks after radiotherapy in patients with head and neck squamous cell carcinoma.

Background: The purpose of this study was to evaluate if a positron emission tomography (PET) scan, 6 weeks post radiotherapy (RT), adequately selects patients in whom a neck node dissection can be omitted. Primary endpoints were isolated neck recurrences and overall survival (OS). Methods: 105 patients, mainly with oropharyngeal human papilloma virus (HPV) positive tumors, with a positive PET sca

Vitronectin in bacterial pathogenesis: A host protein used in complement escape and cellular invasion.

The multifunctional human glycoprotein vitronectin (Vn) plays a significant role in cell migration, tissue repair and regulation of membrane attack complex (MAC) formation. It also promotes neutrophil infiltration and, thus, enhances the inflammatory process during infection. In the host, a balanced homeostasis is maintained by Vn due to neutralization of the self-reactivity of the MAC. On the oth

Functional organization of climbing fibre projection to the cerebellar anterior lobe of the rat

1. The input characteristics and distribution of climbing fibre field potentials evoked by electrical stimulation of various parts of the skin were investigated in the cerebellum of barbiturate anaesthetized rats. 2. Climbing fibre responses were recorded in sagittally oriented microelectrode tracks across the mediolateral width of the anterior lobe. Climbing fibres with similar response latencies

Properties of heavy rainfall in an East Asian monsoon catchment - Analysis of daily rain gauge data

The East Asian monsoon has a strong seasonal effect on the rainfall regime of Eastern China. In order to mitigate floods and conserve the water for use throughout the year, dams and other hydro-structures are built. The design of the structures requires knowledge of the rainfall characteristics that influence the inflow to them. In this thesis, the properties of heavy rainfall in a 73 000 km2 area

Calreticulin binds to the alpha 1 domain of MHC class I independently of tapasin

Prior to binding to antigenic peptide, the major histoconipatibility complex (MHC) heavy chain associates with an assembly complex of proteins that includes calreticulin, tapasin, and the transporter associated with antigen processing (TAP). Our data show that calreticulin can bind weakly to L-d without tapasin's assistance, and that deglycosylation of the alpha1 domain results in a primary loss o

Induction of activating transcription factor 3 after different sciatic nerve injuries in adult rats

Staining by activating transcription factor 3 (ATF3), a neuronal marker of nerve injury, was examined by immunocytochemistry in neurons and Schwann cells after crush or transection (regeneration inhibited) of rat sciatic nerve. ATF3 immunoreactivity peaked in neurons after three days and then gradually subsided to normal within 12 weeks after the crush. The response lasted somewhat longer and decl

A Monte Carlo program for the simulation of scintillation camera characteristics

There is a need for mathematical modelling for the evaluation of important parameters for photon imaging systems. A Monte Carlo program which simulates medical imaging nuclear detectors has been developed. Different materials can be chosen for the detector, a cover and a phantom. Cylindrical, spherical, rectangular and more complex phantom and source shapes can be simulated. Photoelectric, incoher

Computational study of the combustion process and NO formation in a small-scale wood pellet furnace

This paper presents a computational study of the combustion process of wood pellets in a small-scale grate fired furnace. The objectives were to obtain detailed information on the combustion characteristics and NO formation in the furnace, and to examine the effect of secondary air on the combustion process. The simulation results were compared with experimental data in terms of flame temperature

Characterisation of a unipolar charger for droplet aerosols of 0.1-20 mu m in diameter

A charging unit for unipolar charging of cloud and fog droplets has been developed and calibrated regarding ion current, angular distribution of ions, mean droplet charge and droplet charge distribution. The charger is part of the droplet aerosol analyser, which is an instrument used for characterisation of droplets and interstitial particles in atmospheric clouds and fog. Three different calibrat

Quantifying error and uncertainty in CFAST 2.0 temperature predictions

In this paper the predictive capability of the smoke transport model CFAST 2.0 is evaluated for five different scenario configurations. The evaluation is made by statistical analysis according to a methodology presented in an earlier paper. Model predictions and experimental data, previously published, are compared and quantitative measures of the predictive capability are thus derived. With the q

Midterm clinical experience with a complex-shaped detachable platinum coil system for the treatment of cerebral aneurysms: Trufill DCS Orbit detachable coil system registry interim results

PURPOSE: To report an interim analysis of the registry data and evaluate the performance of Trufill DCS Orbit coils in terms of the stability of initial aneurysmal occlusion. MATERIALS AND METHODS: From May 1, 2004, to February 1, 2006, 291 patients with ruptured or unruptured aneurysms were enrolled in a multiple-center global registry from 37 centers in the United States, Europe, and Latin Ameri

An Architecture for Migrating User Interfaces

The MUI project looks at flexible ways of creating user-initiated connections between services in wireless networks. A central idea is to migrate user interfaces from controlled devices to devices with better input/output capabilities. The paper shows the different parts of the MUI architecture, and motivates design choices. An initial implementation and a framework for building MUI services are d

Suppression of binding events via external perturbation with emphasis on QCM

Recent experiments indicate that the external perturbations, related e.g. to high-amplitude shear oscillations of the surface of a quartz crystal microbalance sensor, may suppress binding of mesoscopic aggregates (e.g., polystyrene spheres, vesicles, large proteins, etc.) to the surface. Using a simple kinetic model, we derive equations making it possible to conceptually understand and to mathemat