Sökresultat

Filtyp

Din sökning på "*" gav 531494 sökträffar

Association between low-density lipoprotein cholesterol-lowering genetic variants and risk of type 2 diabetes : A meta-analysis

IMPORTANCE Low-density lipoprotein cholesterol (LDL-C)-lowering alleles in or near NPC1L1 or HMGCR, encoding the respective molecular targets of ezetimibe and statins, have previously been used as proxies to study the efficacy of these lipid-lowering drugs. Alleles near HMGCR are associated with a higher risk of type 2 diabetes, similar to the increased incidence of new-onset diabetes associated w

The Global Prevalence of Infections in Urology (GPUI) Study : A Worldwide Surveillance Study in Urology Patients

The GPIU study is currently the only study registering health care–associated urogenital tract infections, especially in urology patients, in an ongoing surveillance protocol that can help to deliver data on adequate empirical antibiotic therapy in hospitalised urology patients according to guideline recommendations. The annual GPIU study will continue to be performed in November of each year unde

NSAIDs and Cardiovascular Diseases : Role of Reactive Oxygen Species

Nonsteroidal anti-inflammatory drugs (NSAIDs) are the most commonly used drugs worldwide. NSAIDs are used for a variety of conditions including pain, rheumatoid arthritis, and musculoskeletal disorders. The beneficial effects of NSAIDs in reducing or relieving pain are well established, and other benefits such as reducing inflammation and anticancer effects are also documented. The undesirable sid

Endocrine and metabolic diurnal rhythms in young adult men born small vs appropriate for gestational age

OBJECTIVE: Sleep disturbances and alterations of diurnal endocrine rhythms are associated with increased risk of type 2 diabetes (T2D). We previously showed that young men born small for gestational age (SGA) and with increased risk of T2D have elevated fat and decreased glucose oxidation rates during nighttime. In this study, we investigated whether SGA men have an altered diurnal profile of horm

An Energy Efficiency Perspective on Massive MIMO Quantization

One of the basic aspects of Massive MIMO (MaMi) that is in the focus of current investigations is its potential of using low-cost and energy-efficient hardware. It is often claimed that MaMi will allow for using analog-to-digital converters(ADCs) with very low resolutions and that this will result in overall improvement of energy efficiency. In this contribution, we perform a parametric energy eff

The Gaia-ESO Survey : Hydrogen lines in red giants directly trace stellar mass

Red giant stars are perhaps the most important type of stars for Galactic and extra-galactic archaeology: they are luminous, occur in all stellar populations, and their surface temperatures allow precise abundance determinations for many different chemical elements. Yet, the full star formation and enrichment history of a galaxy can be traced directly only if two key observables can be determined

Essentials of Teamcare in Randomized Controlled Trials of Multidisciplinary or Interdisciplinary Interventions in Somatic Care : A Systematic Review

Background: Teamcare should, like all patient care, also contribute to evidence-based practice (EBP). Randomized controlled trials (RCTs) focusing on teamcare have been performed but no study has addressed its essentials. How far this EBP has progressed in different health aspects is generally established in systematic reviews of RCTs. Aim: The aim is to determine the essentials of teamcare includ

High rate of recurrent venous thromboembolism in patients with myeloproliferative neoplasms and effect of prophylaxis with Vitamin K antagonists

The optimal duration of treatment with vitamin K antagonists (VKA) after venous thromboembolism (VTE) in patients with Philadelphia-negative myeloproliferative neoplasms (MPNs) is uncertain. To tackle this issue, we retrospectively studied 206 patients with MPN-related VTE (deep venous thrombosis of the legs and/or pulmonary embolism). After this index event, we recorded over 695 pt-years 45 recur

Generation of central exclusive final states

We present a scheme for the generation of central exclusive final states in the program. The implementation allows for the investigation of higher-order corrections to such exclusive processes as approximated by the initial-state parton shower in . To achieve this, the spin and colour decomposition of the initial-state shower has been worked out, in order to determine the probability that a parton

A new plastic scintillation resin for single-step separation, concentration and measurement of technetium-99

Technetium is a synthetic element with no stable isotopes, produced as waste in nuclear power plants and in cyclotrons used for nuclear medicine. The element has high mobility, in the form of TcO4 −; its determination is therefore important for environmental protection. Technetium is found in low concentrations and therefore common methods for its analysis include long treatments in several steps

Chemotherapeutic intensity and survival differences in young patients with diffuse large B-cell lymphoma : a Swedish Lymphoma Registry study

Young patients with diffuse large B-cell lymphoma (DLBCL) are variably treated with rituximab combined with cyclophosphamide-doxorubicin-vincristine-prednisone (R-CHOP), CHOP-etoposide (R-CHOEP), and anthracycline-based regimens with the addition of high-dose cytarabine/methotrexate (R-HDA/M). Using the nationwide, population-based Swedish Lymphoma Registry, we evaluated outcome, by treatment and

Diabetes mellitus, high BMI and low education level predict sudden cardiac death within 24 hours of incident myocardial infarction

Background More than half of cardiovascular mortality occurs outside the hospital, mainly due to consistently low survival rates from out-of-hospital cardiac arrest. Methods This is a prospective, nested, case-control study derived from the Västerbotten Intervention Programme and the World Health Organization's Multinational Monitoring of Trends and Determinants in Cardiovascular Disease study in

Can dressings soaked with polyhexanide reduce bacterial loads in full-thickness skin grafting? A randomized controlled trial

Background Polyhexamethylene biguanide (PHMB)-based antiseptic solutions can reduce bacterial loads in different clinical settings and are believed to lower risk of infections. Objective We sought to assess the efficacy of a PHMB-based solution in lowering bacterial loads of full-thickness skin grafting wounds and the risk of surgical site infections (SSIs). Methods In this double-blinded clinical

Electrical resistivity tomography and induced polarization for mapping the subsurface of alluvial fans : A case study in Punata (Bolivia)

Conceptual models of aquifer systems can be refined and complemented with geophysical data, and they can assist in understanding hydrogeological properties such as groundwater storage capacity. This research attempts to use geoelectrical methods, Electrical Resistivity Tomography and Induced Polarization parameters, for mapping the subsurface in alluvial fans and to demonstrate its applicability;

Patterns and processes in nocturnal and crepuscular pollination services

Night,dawn,and dusk have abiotic features that differ from the day. Illumination,wind speeds,turbulence,and temperatures are lower while humidity may be higher at night. Nocturnal pollination occurred in 30% of angiosperm families across 68% of orders,97% of families with C3,two-thirds of fam-ilies with crassulacean acid metabolism (CAM),and 71% dicot families with C4 photosynthesis. Despite its w