Objective. To assess the impact of low-to-moderate risk prostate cancer on patients' quality of life (QoL) at diagnosis and within the first year of treatment. Subjects and Methods. Men (n = 672) aged 50-75 years with prostate cancer (Gleason score ≤7, PSA ≤20 ng/mL and clinical staging T1c-T2b) were enrolled in five European countries. Patients completed five questionnaires, including EORTC Quali

It is well known that newly formed planetary systems undergo processes of orbital reconfiguration and planetary migration. As a result, planets or protoplanetary objects may accrete onto the central star, being fused and mixed into its external layers. If the accreted mass is sufficiently high and the star has a sufficiently thin convective envelope, such events may result in a modification of the

In the present study, a simple and reliable antioxidant screening technique based on lactate dehydrogenase (LDH) oxidation by Cu2+-mediated Fenton's reaction has successfully been developed. Oxidation of LDH by hydroxyl radical consequently leads to enzymatic inactivation, while addition of antioxidants can protect and regain enzyme activity. This method demonstrated a high feasibility on detectin

Spatial multiplexing using Massive MIMO has been shown to have very promising properties, including large gains in spectral efficiency and several orders of magnitude lower transmit power, as compared to today's access schemes. The properties of massive MIMO have been studied mostly for theoretical channels with independent and identically distributed (i.i.d.) complex Gaussian coefficients. To eff

We prove that the product of finitely many Toeplitz operators oil the Hardy space is zero if and only if at least one of the operators is zero. We use some new vector-valued techniques that not only lead to a vector-valued version of this result but also appear to be needed in the scalar case.

As one of two well-exposed intraoceanic arcs, the Talkeetna arc of Alaska affords an opportunity to understand processes deep within arcs. This study reports new Lu-Hf and Sm-Nd garnet ages, Ar-40/Ar-39 hornblende, mica and whole-rock ages, and U-Th/He zircon and apatite ages from the Chugach Mountains, Talkeetna Mountains, and Alaska Peninsula, which, in conjunction with existing geochronology, c

Abstract in UndeterminedEnergy future studies can be a useful tool for learning about how to induce and manage technical, economic and policy change related to energy supply and use. The private sector has successfully deployed them for strategic planning, examining key parameters such as markets, competition and consumer trends. However in public policy, most energy future studies remain disconne

The aim of this study is to investigate the physical and chemical properties of particle emissions from candle burning in indoor air. Two representative types of tapered candies were studied during steady burn, sooting burn and smouldering (upon extinction) under controlled conditions in a walk-in stainless steel chamber. Steady burn emits relatively high number emissions of ultrafine particles do

G.fast is a new standard from the International Telecommunication Union, which targets 1 Gb/s over short copper loops using frequencies up to 212 MHz. This new technology requires accurate parametric cable models for simulation, design, and performance evaluation tests. Some existing copper cable models were designed for the very high speed digital subscriber line spectra, i.e., frequencies up to

Given electronic wave functions generated by the grasp2K relativistic atomic structure package, this program calculates diagonal magnetic dipole A(J) and electric quadrupole B-J hyperfine interaction constants and Lande g(J) factors. In addition the program computes diagonal and off-diagonal reduced hyperfine and Zeeman matrix elements and constructs the total interaction matrix for an atom in an

The purpose of this doctoral study is to bring a spatial dimension into the research on urban mobilities and connect the spatial dimension to the marginalisation of cyclists in urban space. This is been done by exploring the role of urban bicycling and transport planning. The theoretical frame of space, mobilities and power is used for analysing that role through case studies in two Scandinavian c

New metastable massive particles with electric and colour charge are features of many theories beyond the Standard Model. A search is performed for long-lived gluino-based R-hadrons with the ATLAS detector at the LHC using a data sample corresponding to an integrated luminosity of 31 pb(-1). We search for evidence of particles that have come to rest in the ATLAS detector and decay at some later ti

Aims P2Y(12) receptor antagonism and platelet inhibition by prasugrel vs. clopidogrel were investigated in patients with stable coronary artery disease. Methods and results One hundred and ten aspirin treated subjects were randomized to double-blind treatment with clopidogrel (n = 55) 600 mg loading dose (LD) and 75 mg maintenance dose (MD) or prasugrel (n = 55) 60 mg LD and 10 mg MD for 28 days.

In this paper, we consider robust stability analysis of large-scale sparsely interconnected uncertain systems. By modeling the interconnections among the subsystems with integral quadratic constraints, we show that robust stability analysis of such systems can be performed by solving a set of sparse linear matrix inequalities. We also show that a sparse formulation of the analysis problem is equiv

Background: Antimicrobial peptides (AMPs) are receiving increasing attention due to resistance development against conventional antibiotics. Pseudomonas aeruginosa and Staphylococcus aureus are two major pathogens involved in an array of infections such as ocular infections, cystic fibrosis, wound and post-surgery infections, and sepsis. The goal of the study was to design novel AMPs against these

Patients with coeliac disease living on a gluten-free diet show vitamin deficiency and reduced subjective health status. To study the biochemical and clinical effects of B vitamin supplementation in adults with longstanding coeliac disease. In a double blind placebo controlled multicentre trial, 65 coeliac patients (61% women) aged 45-64 years on a strict gluten-free diet for several years were ra

One of the key research and policy problems in innovation studies is the development of tools for understanding and measuring the impact of academic research on society. The paper contributes to resolving this problem by providing a typology that helps us to understand and analyse the roles researchers take on in order to make academic knowledge useful. A key finding is that utility creation is co

Triglycerides are transported in plasma by specific triglyceride-rich lipoproteins; in epidemiological studies, increased triglyceride levels correlate with higher risk for coronary artery disease (CAD). However, it is unclear whether this association reflects causal processes. We used 185 common variants recently mapped for plasma lipids (P < 5 x 10(-8) for each) to examine the role of triglyceri