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Popular Abstract in Swedish Leukemi är en cancersjukdom i blod och benmärg som karakteriseras av en störd blodbildning. Vid normal blodbildning delar sig ett begränsat antal omogna blodceller så kallade blod stamceller (eller hematopoietiska stamceller) och mognar till funktionella blodceller. Genom att dela sig utan att mogna har stamcellerna även potential till at förnya sig själva. När nya stamAcute myeloid leukemia (AML) is a malignant disorder of the blood system. Hematopoietic stem cells (HSCs) supply and maintain this system by differentiating via intermediates into lineage-restricted progenitors that strongly proliferate to keep up with the high turn-over of mature blood cells. In AML, the mechanisms controlling differentiation and proliferation of myeloid cells are disturbed leadi

The aim of the study was to explore the development of functioning impairments and symptom occurrence during the last months of life of advanced cancer patients. Self-reported data from 116 patients who all completed the European Organisation for Research and Treatment of Cancer Quality of Life Questionnaire-Core 30 (EORTC QLQ-C30) at 3, 2 and 1 month before death were analysed. All functioning as

Background: Observational studies implicate higher dietary energy density (DED) as a potential risk factor for weight gain and obesity. It has been hypothesized that DED may also be associated with risk of type 2 diabetes (T2D), but limited evidence exists. Therefore, we investigated the association between DED and risk of T2D in a large prospective study with heterogeneity of dietary intake. Meth

Making a detour can be advantageous to a migrating bird if fuel-deposition rates at stopover sites along the detour are considerably higher than at stopover sites along a more direct route. One example of an extensive migratory detour is that of the Sharp-tailed Sandpiper (Calidris acuminata), of which large numbers of juveniles are found during fall migration in western Alaska. These birds take a

Background and purpose The remodeling of morselized bone grafts in revision surgery can be enhanced by an anabolic substance such as a bone morphogenetic protein (BMP). On the other hand, BMPs boost catabolism and might cause a premature resorption, both of the graft and of the new-formed bone. Bisphosphonates inactivate osteoclasts and can be used to control the resorption. We studied a combinati

Popular Abstract in Swedish Denna avhandling har fokus på arbetsrehabilitering för personer som är sjukskrivna eller riskerar att bli det. För dem som blir sjukskrivna kan det bli aktuellt med arbetsrehabilitering. Första steget i en sådan är att utreda individens arbetsförmåga. Utredningen ligger sedan till grund för val av fortsatta åtgärder, för utvärdering av rehabiliteringen samt i vissa falThe overall aim of this thesis was to contribute to the development of new instruments for use in work rehabilitation contexts and to investigate whether clients’ perceptions of their work environment changed while participating in a work rehabilitation programme, as well as how they perceived the programme. The work rehabilitation in focus was the Redesigning Daily Occupations (ReDO) programme. T

Abstract in Undetermined In this anthology, twenty-three scholars from seven academic disciplines analyze film in Sweden never distributed to the cinema. Encompassing more than a centurys, the book gives a broad overview of the role of moving images in relation to the the Swedish model welfare state. The material includes amateur film, education film, industrial film and avant-garde film. The book

Evacuation models generally include the use of distributions or probabilistic variables to simulate the variability of possible human behaviours. A single model setup of the same evacuation scenario may therefore produce a distribution of different occupant-evacuation time curves in the case of the use of a random sampling method. This creates an additional component of uncertainty caused by the i

People have always been inclined not to stick with one god alone, not to trust one single religion. One possible conclusion is that history is full of syncretism. Syncretism seems to be disturbing. It disturbs the exclusive relationship between God and his people, and it disturbs the idea of logical purity if things are mixed up in an uncontrolled manner. Two main attitudes towards syncretism are

The beams extracted from thermal neutron sources such as nuclear reactors are monochromatised by Bragg diffraction using imperfect single crystals with an angular mosaic spread of typically 0.2-0.8 degrees. For neutron wavelengths below 1.5 angstrom, the highest reflectivity of all crystalline materials is expected for diamond. Nowadays diamond single crystals with an appropriate mosaic spread exc

Background: Renal disease remains a serious threat in patients with insulin-dependent (type1) diabetes. Hence its detection early in the life of patients with type1 diabetes is crucial. Several lines of evidence suggest similar mechanisms for the development of both renal and arterial disease. We sought to investigate in young patients with type1 diabetes whether pi-Glutathione S-transferase to cr

I Doktorandbarometern 2007 har över 700 doktorander vid Lunds universitet bidragit med sina erfarenheter av forskarutbildningen. En väsentlig del av dessa erfarenheter var gemensamma, trots att de representerade olika vetenskapsområden. Ett annat intressant resultat visade på betydelsen av doktoranders delaktighet och medarbetarskap i forskarutbildningsmiljön. De som huvudsakligen arbetade inom ra

Industrial fermentation of lignocellulosic hydrolysates to ethanol requires microorganisms able to utilise a broad range of carbon sources and generate ethanol at high yield and productivity. D. bruxellensis has recently been reported to contaminate commercial ethanol processes, where it competes with Saccharomyces cerevisiae [4, 26]. In this work Brettanomyces/Dekkera yeasts were studied to explo

A Monte Carlo method is employed to calculate the dynamical conductivity in the terahertz range of free charge carriers localized in semiconductor nanoparticles. The shape of the conductivity spectrum is essentially determined by the probability of carrier transition through interparticle boundaries and by the ratio of the nanoparticle size and carrier mean free path in the bulk. It is shown that