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Protein recognition via ion-coordinated molecularly imprinted supermacroporous cryogels

Molecular imprinting is a method for making selective binding sites in synthetic polymers using a molecular template. The aim of this study is to prepare lysozyme-imprinted supermacroporous cryogels which can be used for the purification of lysozyme (Lyz) from egg white. N-Methacryloyl-(L)-histiclinemethylester (MAH) was chosen as the metal-coordinating monomer. In the first step, Cu2+ was complex

Weight Suppression and Body Mass Index Interact to Predict Long-Term Weight Outcomes in Adolescent-Onset Anorexia Nervosa

Research on anorexia nervosa (AN) has emphasized the importance of low absolute body weight, but emerging research suggests the importance of also considering low body weight relative to an individual's highest premorbid weight (weight suppression; WS). Objective: We investigated whether body mass index and WS at lowest weight (BMI-LW and WS-LW) among adolescents with AN predicted BMI at 6-, 10-,

Tryggheten inför rätta : Om rätten till förtidspension enligt förvaltningsdomstolarna under tre decennier

Popular Abstract in Swedish Under de senaste åren har förtidspensionen och dess funktionssätt hamnat i fokus för den politiska debatten. Behovet av en förnyad, anpassad och mer ekonomiskt hållbar försäkring har framförts i politiska diskussioner, offentliga utredningar och inom forskarsamhället sedan början av 1990-talet. Samtidigt har kritik riktats mot att det finns skillnader och glidningar i fThe Swedish disability pension program has been a recurring topic for political debate. Through the years the need for an adjusted and financially stable insurance has been commented on by politicians and by scholars. Numerous government reports have tackled both the costs of the program and the growing number of people granted disability pensions. During the last ten years the disability pension

Willingness to Pay and Sensitivity to Time Framing: A Theoretical Analysis and an Application on Car Safety

Stated preference (SP) surveys attempt to obtain monetary values for non-market goods that reflect individuals’ “true” preferences. Numerous empirical studies suggest that monetary values from SP studies are sensitive to survey design and so may not reflect respondents’ true preferences. This study examines the effect of time framing on respondents’ willingness to pay (WTP) for car safety. We expl

Testing the predictive capabilities of evacuation models for tunnel fire safety analysis

The scope of this paper is to test the predictive capabilities of different evacuation modelling approaches to simulate tunnel fire evacuations. The study is based on the a priori modelling (prior to the experiments) vs a posteriori modelling (after the data collection stage) of a set of tunnel evacuation experiments performed in a tunnel in Stockholm, Sweden. Different degrees of modelling sophis

Alteration in contractile G-protein coupled receptor expression by moist snus and nicotine in rat cerebral arteries

The cardiovascular risk for users of use of Swedish snus/American snuff (moist tobacco) has been debated for a long time. The present study was designed to examine the effects of water- or lipid-soluble (DMSO-soluble) snus and nicotine, the most important substance in tobacco, on the expression of vasocontractile G-protein coupled receptors (GPCR), such as endothelin ETB, serotonin 5-HT1B, and thr

Aral Sea syndrome desiccates Lake Urmia: Call for action

Lake Urmia, one of the largest saltwater lakes on earth and a highly endangered ecosystem, is on the brink of a major environmental disaster similar to the catastrophic death of the Aral Sea. With a new composite of multi-spectral high resolution satellite observations, we show that the area of this Iranian lake has decreased by around 88% in the past decades, far more than previously reported (~

Adaptation of Scheffersomyces stipitis to hardwood spent sulfite liquor by evolutionary engineering

Background: Hardwood spent sulfite liquor (HSSL) is a by-product of acid sulfite pulping process that is rich in xylose, a monosaccharide that can be fermented to ethanol by Scheffersomyces stipitis. However, HSSL also contains acetic acid and lignosulfonates that are inhibitory compounds of yeast growth. The main objective of this study was the use of an evolutionary engineering strategy to obtai

Psalm, hymn och andlig visa : Hymnologiska studier

This volume 90 of the Yearbook for Swedish Liturgical Life is dedicated to hymnological studies. It includes articles by Ingvar Bengtsson, Stephan Borgehammar, Anna J. Evertsson, Liza L Lundkvist & Ragnar Holte. All articles are in Swedish with a summary in English.

A model of the complex between human beta-microseminoprotein and CRISP-3 based on NMR data.

beta-Microseminoprotein (MSP), a 10kDa seminal plasma protein, forms a tight complex with cysteine-rich secretory protein 3 (CRISP-3) from granulocytes. The 3D structure of human MSP has been determined but there is as yet no 3D structure for CRISP-3. We have now studied the complex between human MSP and CRISP-3 with multidimensional NMR. (15)N-HSQC spectra show substantial differences between fre

Monitoring the Multi-Year Carbon Balance of a Subarctic Palsa Mire with Micrometeorological Techniques

This article reports a dataset on 8 years of monitoring carbon fluxes in a subarctic palsa mire based on micrometeorological eddy covariance measurements. The mire is a complex with wet minerotrophic areas and elevated dry palsa as well as intermediate sub-ecosystems. The measurements document primarily the emission originating from the wet parts of the mire dominated by a rather homogenous cover

Trade-Offs Between Forest Protection and Wood Supply in Europe

Forest protection is one of the main measures to prevent loss of biological and landscape diversity. This study aimed to assess to what extent forests are currently protected and how felling restrictions affect the potential annual wood supply within 27 European Union member states, Norway, and Switzerland and to discuss trade-offs between intensified use of forest biomass and forest protection ef

Engineering of Saccharomyces cerevisiae for the production of poly-3-d-hydroxybutyrate from xylose.

Poly-3-d-hydroxybutyrate (PHB) is a promising biopolymer naturally produced by several bacterial species. In the present study, the robust baker's yeast Saccharomyces cerevisiae was engineered to produce PHB from xylose, the main pentose found in lignocellulosic biomass. The PHB pathway genes from the well-characterized PHB producer Cupriavidus necator were introduced in recombinant S. cerevisiae

Hierarchical Scheduling and Utility Disturbance Management in the Process Industry

This thesis deals with control of production at large-scale process industrial sites in the presence of disturbances. The main focus is on disturbances in the supply of utilities such as steam, cooling water and electricity. A general method for reducing the revenue loss due to disturbances in utilities is introduced, which may provide both proactive and reactive disturbance management strategies.

The impact of Bcl-3 expression and signaling in cancer

Popular Abstract in English Resistant to drug induced apoptosis and uncontrolled proliferation are biggest hurdles of cancer treatment. Bcl-3 is a proto-oncogene involved in both survival and proliferation in numerous cancers. In this thesis we investigated the molecular mechanisms through which Bcl-3 facilitates the survival and proliferation of cancer cells, furthermore we aimed to identify the Bcl-3 is a proto-oncogene and belongs to the inhibitor of κB (IκB) family and is known to be upregulated in numerous cancers. Bcl-3 can initiate transcription of different genes involved in cell survival and cell growth. Cell proliferation is achieved through binding of Bcl-3 to cyclin D1 promoter and facilitates the rapid transition from G1 to S phase. The aim of this thesis was to investigate th

Elemental composition of arbuscular mycorrhizal fungi at high salinity.

We investigated the elemental composition of spores and hyphae of arbuscular mycorrhizal fungi (AMF) collected from two saline sites at the desert border in Tunisia, and of Glomus intraradices grown in vitro with or without addition of NaCl to the medium, by proton-induced X-ray emission. We compared the elemental composition of the field AMF to those of the soil and the associated plants. The spo

Use of nonlinear upconverting nanoparticles provide increased spatial resolution in fluorescence diffuse imaging

Fluorescence diffuse imaging suffers from limited spatial resolution. In this letter, we report a scanning imaging approach to increase the resolution of fluorescence diffuse imaging using nonlinear fluorophores. The resolution of a linear flurophore was compared with nonlinear upconverting nanoparticles (NaYF4 : Yb3+ /Tm3+ ) in a tissue phantom. A resolution improvement of a factor of 1.3 was fou