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Regulation and Function of the Human Leukotriene D4 Receptor CysLT1 in Epithelial Cells and Colon Cancer

Popular Abstract in Swedish Betændelses reaktionen er kroppens svar på en skade eller en infektion. Betændelses reaktionen gør at immunforsvarets celler kaldes til det skadede område (kan ses som den røde varme hævelse omkring et sår) og at eventuelle sygdomsfremkaldende emner identificeres og bekæmpes. På lidt længere sigt, fjernes ødelagt væv og helingen af såret påbegyndes. Når det skadede områThe pro-inflammatory mediators leukotrienes have shown to be important players in the pathogenesis of diseases like asthma and inflammatory bowel disease (IBD). Patients suffering from IBD have been found to have an increased risk of developing colon cancer. Since leukotrienes have been shown in increased concentrations in stools of IBD patients we hypothesise that LTD4 can play a role in the deve

Characterization of Secondary Metabolites from Natural Sources

Natural products have contributed for many years to the development of new medicines for the treatment of diseases. Their structural diversity and complexity have inspired chemists to produce interesting compounds with pharmaceutical use. Although many pharmaceutical companies have eliminated or scaled down their natural products research, they still remain an important source of new drugs. This

Experience of Policy Instruments for Energy Efficiency in Buildings in the Nordic Countries

The Nordic countries have often been seen as “fore-runners” of energy efficiency in buildings in terms of both 1) the implementation of policy instruments and 2) the evaluation of actual effects. Since the 1970s, the Nordic countries have introduced a range of policy instruments for energy conservation in buildings. Interestingly, there are contrasting policy “styles” and experiences across the No

Improved MALDI-TOF-MS analysis of partially depolymerised methyl cellulose by reducing end derivatisation

The depolymerized methyl cellulose was analyzed, using improved MALDI-TOF-MS by reducing the end derivatization. The methyl cellulose was depolymerized to give methylated oligo-(1->4)-β-D-anhydroglucoses (M-oligo-AG). To reduce the errors during measurement of degree of substitution (DS), M-oligo-AG was derivatized with Girard's T reagent performed on an equimolar mixture of maltooligosaccharides.

Från klarhet till klarhet. Lysande texter för sociologisk forskning

Samhällsvetenskaplig forskning äger vanligen rum ytterst stillsamt, bland högar av papper och böcker, vid datorskärmar och på seminarier. Men ibland händer det något. En dag kan man få tag i en text som hjälper en att skärpa blicken, få ordning på intrycken och energi nog att börja argumentera. Materialet faller på plats och forskningen går faktiskt framåt. Det handlar om teoretiska händelser –