In 131I SPECT, image quality and quantification accuracy are degraded by object scatter as well as scatter and penetration in the collimator. The characterization of energy and spatial distributions of scatter and penetration performed in this study by Monte Carlo simulation will be useful for the development and evaluation of techniques that compensate for such events in 131I imaging. METHODS: Fi

Efficient protein synthesis in bacteria requires initiation factor 2 (IF2), elongation factors Tu (EF-Tu) and G (EF-G), and release factor 3 (RF3), each of which catalyzes a major step of translation in a GTP-dependent fashion. Previous reports have suggested that recruitment of factors to the ribosome and subsequent GTP hydrolysis involve the dimeric protein L12, which forms a flexible "stalk" on

In an attempt to gain information about the identity of the Golgi apparatus casein kinase(s) (G-CK), responsible for the phosphorylation of caseins in lactating mammary gland, the proteins present in fractions enriched in G-CK activity eluted from DEAE-Sepharose and heparin-Sepharose columns were resolved by two-dimensional electrophoresis and analyzed by mass spectrometry. This led to the identif

The syntheses of various amino- and hydroxy-substituted dehydrophenylalanine derivatives using the Heck-Jeffery protocol under non-solvent conditions in a ball mill are presented. The influences of electron-withdrawing groups and of the location of the heteroatom substituent relative to the halide are discussed. Suitably substituted ortho-amino dehydrophenylalanine derivatives undergo a cyclizatio

We examinedfactors that may influence the development of arm lymphedema following breast cancer treatment including the specific mode of therapy, patient occupation and life style. Medical record data and a questionnaire were used to collect information after surgery concerning such issues as wound seroma, infection, adjuvant treatment, vessel string (phlebitis), body mass index, smoking habits an

Increased levels of inflammatory mediators such as cystenyl leukotrienes (CysLT) have been found in and around tumors. These data, along with our previous observation that the G-protein-coupled receptor CysLT(1)R, which signals survival and proliferation, is up-regulated in colon cancer, suggest an important role for CysLT(1)R in tumor development. The objective of this study was to examine the ex

The fine-structure splitting of the 42D state in lithium was measured using stepwise laser excitation combined with level-crossing spectroscopy. The splitting was determined to be 456.2(0.8) MHz, a considerably higher value than the one obtained in a recent level-anticrossing measurement. The new value is in good agreement with the result of a Hartree-Fock calculation, 460.2 MHz.

We aimed to study trends in gender-related differences in incidence, and prevalence for tong-term oxygen therapy due to chronic obstructive pulmonary disease. Another aim was to study survival after onset of oxygen therapy. Prospectively followed were 5689 Swedish patients, who were prescribed oxygen therapy because of chronic obstructive pulmonary disease from 1987 to 2000. The annual incidence o

Kåserande artikel om skilda former av resande förr och idag, arbetsvandringar och studieresor, hantverkare och soldater. Om ovälkomna resenärer och tendensen att peka ut syndabockar, behovet av källkritik. Gunnar Ståhl: "Resenärer i arkiven". Referat av föredrag.

Optimizing pharmacokinetic/pharmacodynamic indices of antibiotics to obtain clinical and microbiological efficacy is essential, but dosing regimens must also be tailored to minimize the risk for emergence of resistance. The aim of the present study was to investigate whether certain concentrations of benzylpenicillin are critical for the selection of resistant subpopulations. A mixed culture of St

Streptococcus pneumoniae isolates of serotypes 1, 4, 6B, 7F, 14, and 19F belonging to clonal types with known invasive disease potential in humans were used to infect C57BL/6 and BALB/c mice. Most isolates were able to colonize the nasopharynx for 7 days. One serotype 19F isolate of the clonal type ST162 had higher bacterial numbers than other isolates and clonal types of the same serotype. Seroty

Many birds feed on submerged macrophytes during a temporally discrete period every year, for instance during migratory stopover or at the wintering grounds. Hence, seasonal herbivory is a common feature of the life cycle in many aquatic macrophytes. We are interested in the effect of Bewick's swans (Cygnus columbianus bewickii) feeding on the tubers of fennel pondweed (Potamogeton pectinatus) in t

Objective. Helicobacter pylori infection is an established risk factor for non-cardia gastric adenocarcinoma. Infection with H. pylori strains harbouring the cagA pathology island may augment this association. H. pylori infection may at the same time reduce the risk for oesophageal carcinoma. However, prospective data on the association between CagA seropositivity and gastric or oesophageal carcin

The ground volume is penetrated by a duct system for injection and extraction of heat. The heat transfer properties between the ground and such a system is here characterized by a heat transfer length. The heat exchange between the soil and the ducts is represented by a heat source/sink distribution in the storage region.

Physicochemical changes of dietary fibre in the presence of NaCl or CaCl2 (0, 100 or 400 mM) during boiling (4 or 25 min) of blanched/frozen carrots were investigated, Addition of NaCl (100 mM) to the boiling water reduced total dietary fibre (TDF) content, due to a reduction of insoluble polymers. Higher concentrations had no further effects. NaCl showed minor effects, on molecular weight distrib