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Aims Ticagrelor is associated with a lower risk of ischemic events than clopidogrel. However, it is uncertain whether the benefits of more intensive anti-ischemic therapy outweigh the risks of major bleeding in patients who have a high bleeding risk (HBR). Therefore, this study compared ticagrelor and clopidogrel in myocardial infarction (MI) patients with HBR. Methods and results This study inclu

We report metallicities for three ∼Gyr-old stars in the Milky Way nuclear star cluster (NSC) using high-resolution near-infrared spectroscopy. We derive effective temperatures from a calibration with Sc line strength, which yields results in good agreement with other methods, and metallicities from spectral fits to Fe i lines. Our derived metallicities range from −1.2 < [Fe/H] < + 0.5, a span of 1

Objectives: This is a protocol for a Cochrane Review (intervention). The objectives are as follows:. To assess the benefits and harms of decongestants and antihistamines in the treatment of AOM in children. Specifically, we want to assess the impact of decongestants and antihistamines on the presence of otalgia, the persistence of AOM, the need for or change in antibiotic therapy, severe complicat

Very fast interface traps have recently been suggested to be the main cause behind poor channel-carrier mobility in SiC metal-oxide-semiconductor field effect transistors. It has been hypothesized that the NI traps are defects located inside the SiO2 dielectric with energy levels close to the SiC conduction band edge and the observed conductance spectroscopy signal is a result of electron tunnelin

The acini-islet-acinar (AIA) axis concept justifies the anatomical placement of the Langerhans islets within the exocrine pancreatic parenchyma and explains the existence of the pancreas as a single organ. Amylase has been suggested to play a key role as an anti-incretin factor. Oral glucose tolerance tests (OGTT) were performed on 18 piglets in both a healthy (prior to pancreatic duct ligation (P

We introduce a new technique, that we dub Born spreading, aimed at reducing the number of negative-weight S events in the MC@NLO matching of NLO calculations with parton-shower simulations. We show that such a technique, based on a re-distribution of Born matrix elements in the radiative phase space, achieves a sizeable reduction of negative-weight events at little computational cost. The method d

Multiconfigurational pair-density functional theory (MC-PDFT) is a promising way to describe both strong and dynamic correlations in an inexpensive way. The functionals in MC-PDFT are often “translated” from standard spin density functionals. However, these translated functionals can in principle lead to “translated spin densities” with a nonzero imaginary component. Current developments so far ne

Recent studies have identified increasing levels of nanoplastic pollution in the environment. Here, we find that anionic nanoplastic contaminants potently precipitate the formation and propagation of α-synuclein protein fibrils through a high-affinity interaction with the amphipathic and non-amyloid component (NAC) domains in α-synuclein. Nanoplastics can internalize in neurons through clathrin-de

Iraqi born immigrants in Sweden have higher prevalence of metabolic diseases compared to native Swedes. Copeptin, a marker for vasopressin, is associated with increased risk of metabolic disease. In this cross-sectional population study based on the MEDIM cohort we investigated differences in copeptin levels between Iraqi and Swedish born individuals and if the association between copeptin and car

Al x Ga 1 − x N/GaN high-electron-mobility transistor (HEMT) structures are key components in electronic devices operating at gigahertz or higher frequencies. In order to optimize such HEMT structures, understanding their electronic response at high frequencies and room temperature is required. Here, we present a study of the room temperature free charge carrier properties of the two-dimensional e

Added insulation in cold attics can be an efficient and profitable energy efficiency measure. Simultaneously, added insulation increases the risk of a decreased temperature in the attic, thereby increasing the risk of high relative humidity and moisture damage. This paper collocates and reviews previous publications that deal with the impact of added insulation on attics as a renovation measure. T

Lately there has been an increasing focus on saving peak power in heating systems as a way to lower the environmental load past just saving energy. At the same time, active cooling is becoming increasingly interesting. Sweden has more and more cooling systems with an increase in cooling also in residential buildings. The cooling power is much more expensive than the heating power. Therefore, there

We aimed (i) to gain a better understanding of the demographic and socioeconomical distribution of ADHD risk in Sweden; and (ii) to contribute to the critical discussion on medicalization, i.e., the tendency to define and treat behavioural and social problems as medical entities. For this purpose, we analysed the risk of suffering from ADHD in the whole Swedish population aged between 5 and 60 yea

When assessing the moisture damage risks of different external wall designs using hygrothermal simulation software, the user of said software can choose between different inputs for the determination of the indoor climate. This paper aims to compare results from field measurements in three Swedish buildings using different standards available in a widely used commercial hygrothermal simulation sof

Isobutanol, one of the four isomers of butanol (C4H9OH), possesses some favorable properties that make it an attractive fuel for internal combustion engines. For instance, when compared to ethanol, isobutanol features a higher heating value and lower hygroscopicity (which prevents corrosion and enables it to be transported via pipelines). Moreover, its addition to gasoline does not distort the fue

Standardized Cancer Patient Pathways (CPPs) were introduced in Swedish healthcare starting in 2015 to improve diagnostics for patients with symptoms of cancer, patient satisfaction and equity of care between healthcare providers. An inclusion target and a time target were set. Our primary aim was to visualize the patient population going through CPPs, in terms of investigation time and indications

I Ekonomisk Debatt nummer 5 2023 publicerade vi en artikel där vi studeradeorsakerna bakom kronförsvagningen mot euron (Andersson och Jonung2023). Eftersom kronan tappat i värde över en längre tid valde vi ett långsiktigt perspektiv. Här utgick vi från Cassels köpkraftsparitetsteori och visadeatt svenska priser och nominella löner stigit snabbare än i euroområdet. Kronförsvagningen är ett resultat

An Extended Triple Collocation for maximized Correlation (ETCC) method was proposed with a unique correlation function, the purpose of which is to maximize the correlation between the merged product and unknown truth. The method was tested over quasi-global land by combining three independent precipitation products. The performance of the ETCC-merged product was then evaluated against three refere

In recent years, there have been notable advancements in the ability to programme human cell identity, enabling us to design and manipulate cell function in a Petri dish. However, current protocols for generating target cell types often lack efficiency and precision, resulting in engineered cells that do not fully replicate the desired identity or functional output. This applies to different metho

Introduction: To develop the diving capacity in the Swedish armed forces the current air decompression tables are under revision. A new decompression table named SWEN21 has been created to have a projected risk level of 1% for decompression sickness (DCS) at the no stop limits. The aim of this study was to evaluate the safety of SWEN21 through the measurement of venous gas emboli (VGE) in a dive s