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The pathologic mechanisms of chronic obstructive pulmonary disease (COPD) most certainly involves neutrophil granulocytes, cytotoxic T-cells, macophages and mast cells. The aim of this study was to investigate the relation between the number of mast cells in different compartments in bronchial biopsies of central proximal airways to structural changes, lung function tests and emphysema detected by

Analys av Alfred Hitchcocks användning av musik

Accuracy levels of metres per second require the fundamental concept of``radial velocity'' for stars and other distant objects to be examined,both as a physical velocity, and as measured by spectroscopic andastrometric techniques. Already in a classical (non-relativistic)framework the line-of-sight velocity component is an ambiguous concept,depending on whether, e.g., the time of light emission (a

A large empirical literature suggests the performance characteristics of firms that export are different from firms that do not. Specifically, exporters tend to be larger, more productive and pay higher wages than non-exporters. This paper reports on an econometric analysis of the characteristics of exporters and nonexporters in Swedish manufacturing industry. We use matching and difference-in-dif

The transition from a-helix to random coil of the titrating polyamino acid Co-poly-L-(lysine, phenylalanine), (p-(Lys,Phe)), has been investigated as a function of pH and ionic strength in aqueous solution and at the air water interface by means of circular dichroism (CD) spectroscopy and the Langmuir surface film balance technique. The results strongly suggest that the helix-coil transition for p

Technical progress was for a long time uncontroversial in the Scandinavian left and labor movements. World events like the American war in Vietnam and a new zeitgeist changed this at the end of the sixties and politically aware computer enthusiasts started seeing computers in a new light. Three themes were central in the Swedish discussion: the IBM hegemony, computers, personal privacy, and the th

In an environment full of potential pathogens it is of importance for organisms to mount a fast and effective defence. Antimicrobial peptides are ancient and integral effector molecules of the innate immune system. They are found in all kinds of species from bacteria to plants and animals, indicating their importance during evolution. They possess a broad-spectrum antimicrobial activity and some p

Aims. In this paper we demonstrate how Stromgren uvby photometry can be efficiently used to: 1. identify red giant branch stars that are members in a dwarf spheroidal galaxy; 2. derive age-independent metallicities for the same stars and quantify the associated errors. Methods. Stromgren uvby photometry in a 11 x 22 arcmin field centered on the Draco dwarf spheroidal galaxy was obtained using the

A measurement is presented of elastic deeply virtual Compton scattering gamma* p -> gamma p made using e(+) p collision data corresponding to a luminosity of 46.5 pb(-1), taken with the H1 detector at HERA. The cross section is measured as a function of the photon virtuality, Q(2), the invariant mass of the gamma* p system, W, and for the first time, differentially in the squared momentum transfer

This paper examines data from English, Swedish and German in order to find a theoretical distribution that describes the observed relation between word length and frequency. In Swedish and English, most word tokens consist of three letters only, while shorter or longer words occur less frequently. We found that the equation with the general form fexp = a * Lb * cL (a variant of the so-called gamma

Linear enamel hypoplasia (LEH) is transverse lines or bands on the enamel of teeth caused by developmental stress during the formation of the tooth crown. LEH has shown to be useful as a stress marker in studies of health conditions in past populations of pigs. The chronology of LEH and the age at which animals of past populations where afflicted by metabolic stress can be determined based on toot

Hormone-sensitive lipase (HSL) plays a key role in lipid metabolism and overall energy homoeostasis, by controlling the release of fatty acids from stored triglycerides in adipose tissue. Lipases and esterases form a protein superfamily with a common structural fold, called the alpha/beta-hydrolase fold, and a catalytic triad of serine, aspartic or glutamic acid and histidine. Previous alignments

We describe an experimental test of whether particle decay causes wave function collapse. The test uses interference between two well separated, but coherent, sources of vector mesons. The short-lived mesons decay before their wave functions can overlap, so any interference must involve identical final states. Unlike previous tests of non-locality, the interference involves continuous variables, m

The incidence of post-transfusion hepatitis non-A, non-B (PTH-NANB) was prospectively assessed among open-heart surgery patients from the southeast region of Sweden before the introduction of antihepatitis C virus (HCV) blood donor screening. Blood samples for alanine aminotransferase analysis were drawn before and 2, 3, and 4 months after transfusion. Surgery was performed in four centres. Of 190

There is an increasing amount of knowledge on the cytotoxic properties of cyanotoxins, but relatively little is known regarding their fine specificity and mechanisms of action. In this study, we investigated the influence of microcystin-LR and AnTx-a on mouse B- and T-lymphocyte subpopulations in vitro. Cyanotoxins significantly decreased the cell viability after 4 and 24 h, compared to the untrea

Popular Abstract in Swedish Alla levande organismer består av celler som tillsammans med molekyler generellt kallade extracellulär matrix bildar en vävnad. Celler innehåller fyra huvudgrupper av byggstenar: socker, fettsyror, aminosyror och nukleotider, vilka i tur och ordning bildar kolhydrater, fetter, proteiner och nukleinsyror. I vävnaderna pågår en ständig omsättning av byggstenarna och molekThis thesis describes structural and functional studies of alpha-1-microglobulin (a1m), a 26 kDa plasma and tissue protein that is evolutionarily well-conserved and belongs to the lipocalin superfamily. The lipocalins are polypeptides of 160-190-amino acids that are folded into an 8-stranded beta-barrel forming a pocket with a hydrophobic interior. a1m carries heterogeneous yellow-brown chromophor