We will present results from a recently completed research project financed by BFUF (the R&D Fund of the Swedish Tourism & Hospitality Industry). We have explored German tourists and how they search for tourist information at home and while travelling in Sweden. The overall aim was to understand how tourists’ information search behaviour affects the choice of attractions. The project has b

BACKGROUND: Many studies have indicated that colon and rectal cancers differ in etiology and histology. OBJECTIVE: The aim of this study was to investigate whether the associations of colon and rectal cancers with any other (discordant) cancer were site specific. DESIGN: A novel approach was implemented in which cancer risks were analyzed in families with increasing numbers of family members diagn

BACKGROUND: The dual mobility acetabular cup (DMC) was designed to reduce prosthetic instability and has gained popularity for both primary and revision total hip arthroplasty (THA). We compared the risk of revision of primary THA for primary osteoarthritis between patients treated with a DMC and those who received a metal-on-polyethylene (MoP) or ceramic-on-polyethylene (CoP) bearing. METHODS: A

Innovation within companies is generated by a combination of different types of knowledge from external and geographically dispersed sources. Although the geographical dimension of collaboration has previously been investigated, studies have not distinguished between different types of knowledge involved in collaboration. This article analyses how the number of collaborations between pharmaceutica

Transient oligomeric species formed during the aggregation process of the 42-residue form of the amyloid-β peptide (Aβ42) are key pathogenic agents in Alzheimer’s disease (AD). To investigate the relationship between Aβ42 aggregation and its cytotoxicity and the influence of a potential drug on both phenomena, we have studied the effects of trodusquemine. This aminosterol enhances the rate of aggr

Fusion gene detection is of great diagnostic value since the presence of fusion genes may dictate treatment and patient outcome. When detecting fusion genes in clinical samples there are multiple aspects to consider regarding sample origin, choice of fusion gene detection technique, and data analysis.

Livets minsta byggstenar är celler (från latinets cella; litet rum). Hos encelliga djur, t. ex bakterier och jäst innehåller de enskilda cellerna allt som behövs för att leva och föröka sig. Hos flercelliga organismer är cellerna specialiserade och bygger tillsammans med andra specialiserade celler upp vävnader, organ och hela organismer. Gemensamt för alla celler är att de utvändigt omsluts av etAquaporins (AQPs) are membrane-bound intrinsic water channels that allow the passive diffusion of water and small solutes across cellular membranes. There are 13 highly conserved isoforms of these channels in human, which differ in specificity, regulation and localisation in cells and tissues. The work in this thesis focuses on AQP0 and AQP2; water-specific aquaporins that are known to interact wi

In this study, we report on the three-dimensional (3D) characterization of a spray in terms of its droplet Sautermean diameter (SMD) using the laser-induced fluorescence (LIF)/Mie ratio technique. The spray structure isanalyzed for a multi-hole direct-injection spark ignition (DISI) injector. A calibration curve to convert theLIF/Mie ratio to droplet diameter is deduced using LIF/Mie imaging and a

PURPOSE OF REVIEW: The purpose of this review is to systematically review the literature linking di-2-ethylhexyl phthalate (DEHP) exposure with effects on reproductive health in adult males. RECENT FINDINGS: Thirty-three papers were included of which 28 were cross-sectional. Twenty-one papers investigated semen samples, 18 investigated reproductive hormones, and three studies investigated time to

62 former patients, who had been treated at our department for tibial shaft fracture (n 38) or knee ligament injury (n 24) 15-38 years earlier, were re-evaluated for post-traumatic osteopenia. 62 age- and sex-matched subjects without fracture served as controls. By means of a Lunar DEXA apparatus we measured the bone mineral density (BMD) in the total body, the hips and special regions of interest

This review focuses on the most recent literature concerning flow cytometry (FCM) application for diagnosis of myelodysplastic syndrome (MDS). Aberrant FCM results have been defined as abnormalities in at least three tested features comprising at least two bone marrow (BM) cell compartments. FCM results should be interpreted together with the BM smear cytology, the morphological assessment of BM b

Human alpha 1-m microglobulin (alpha 1-m), a low molecular weight plasma protein, was found to exert mitogenic effects on mouse lymphocytes from lymph nodes and spleen. The stimulatory effects appeared to be strain-restricted: alpha 1-m induced a varying degree of proliferation of lymphocytes from three strains, whereas one strain responded poorly. Experiments with lymphocyte subpopulations showed

The research framework of eco-evolutionary dynamics is increasing in popularity, as revealed by a steady stream of review articles and a recent and influential book, but primary empirical research is lagging behind. Moreover, the few empirical case studies demonstrating eco-evolutionary dynamics might not be entirely representative. Much current research on eco-evolutionary dynamics is focused on

A search for a heavy neutral Higgs boson, A, decaying into a Z boson and another heavy Higgs boson, H, is performed using a data sample corresponding to an integrated luminosity of 36.1 fb−1 from proton–proton collisions at s=13 TeV recorded in 2015 and 2016 by the ATLAS detector at the Large Hadron Collider. The search considers the Z boson decaying to electrons or muons and the H boson into a pa

Background: Hyperthyroidism is a rare disorder which may negatively affect health and quality of life. Its occurrence in childhood cancer survivors has not previously been investigated in detail. Material and methods: In the hospital registers of the five Nordic countries, 32,944 childhood cancer survivors and 212,675 population comparisons were followed for the diagnosis of hyperthyroidism. Hospi