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Regulatory B (Breg) cells can dampen inflammation, autoreactivity and transplant rejection. We investigated the frequencies, phenotypes and function of Breg cells in granulomatosis with polyangiitis (GPA) to gain further knowledge to whether there are numerical alterations or limitations of their ability to regulate T-cell function. Frequencies and phenotypes of CD24 hiCD27 + and CD24 hiCD38 hi B-

This paper presents the foundations of a transrelational theory of moral agency, which extends the relational view with the idea that moral relationships include as well as transcend the descriptive criteria – e.g., in virtue of 1st person properties or 3rd person observables – of whatever makes someone a moral agent. The resultis a holistic picture that captures the complex interrelationship betwThis paper presents the foundations of a transrelational theory of moral agency, which extends the relational view with the idea that moral relationships include as well as transcend the descriptive criteria – e.g., in virtue of 1st person properties or 3rd person observables – of whatever makes someone a moral agent. The result is a holistic picture that captures the complex interrelationship bet

Reconfigurable Intelligent Surfaces (RIS) are well established as a promising solution to the blockage problem in millimeter-wave (mm-wave) and terahertz (THz) communications, envisioned to serve demanding networking applications, such as 6G and vehicular. HyperSurfaces (HSF) is a revolutionary enabling technology for RIS, complementing Software Defined Metasurfaces (SDM) with an embedded network

Programmable metasurfaces constitute an emerging paradigm, envisaged to become a key enabling technology for Reconfigurable Intelligent Surfaces (RIS) due to their powerful control over electromagnetic waves. The HyperSurface (HSF) paradigm takes one step further by embedding a network of customized integrated circuit (IC) controllers within the device with the aim of adding intelligence, connecti

HyperSurfaces (HSFs) consist of structurally reconfigurable metasurfaces whose electromagnetic properties can be changed via a software interface, using an embedded miniaturized network of controllers. With the HSF controllers, interconnected in an irregular, near-Manhattan geometry, we propose a robust, deterministic Fault-Tolerant (FT), deadlockand livelock-free routing protocol where faults are

Probabilistic flooding is commonly considered in vehicular ad-hoc networks (VANETs) to alleviate the celebrated broadcast storm problem. Heuristics and simulations have so far proved to be an efficient way with which to design probabilistic information dissemination solutions with demonstrated effectiveness. Supplementing with mathematical analysis for both design and evaluation is expected to gen

In this paper we model the criminal standard of proof as a twofold standard requiring sufficient probability of the factum probandum and sufficient informativeness. The focus of the paper is on the latter requirement, and we use decision theory to develop a model for sufficient informativeness. We demonstrate that sufficient informativeness is fundamentally a question of information economics and

BACKGROUND: To have an impact on the population's health, preventive interventions have to reach a large proportion of the intended population. Digital solutions show potential for providing wider access to fall preventive exercise. However, there is a lack of knowledge about how to reach the target group. The aim of this study was to describe the recruitment process used in the Safe Step randomis

Objective: To identify subgroups of patients with magnetic resonance imaging (MRI)-confirmed degenerative meniscus tears who may benefit from arthroscopic partial meniscectomy (APM) in comparison with non-surgical or sham treatment. Methods: Individual participant data (IPD) from four RCTs were pooled (605 patients, mean age: 55 (SD: 7.5), 52.4% female) as to investigate the effectiveness of APM i

Mangroves are woody plant communities that appear in tropical and subtropical regions, mainly in intertidal zones along the coastlines. Despite their considerable benefits to humans and the surrounding environment, their existence is threatened by anthropogenic activities and natural drivers. Accordingly, it is vital to conduct efficient efforts to increase mangrove plantations by identifying suit

Southwest China has been the largest terrestrial carbon sink in China over the past 30 years, but has recently experienced a succession of droughts caused by high precipitation variability, potentially threatening vegetation productivity in the region. Yet, the impact of precipitation anomalies on the vegetation primary productivity is poorly known. We used an asymmetry index (AI) to explore possi

Family Report: Two rare autosomal recessive neurological disorders, leukoencephalopathy with ataxia and spastic paraplegia 56 (SPG56), were found in members of the same family. Two siblings presented with spastic paraplegia, cognitive impairment, bladder and bowel dysfunction and gait ataxia; their consanguineous parents were unaffected. Ophthalmological examination revealed chorioretinopathy. Bra

En antologi som belyser den geopolitiska friktionen mellan ekonomisk integration och nationell politisk suveränitet i en sammankopplad värld.

Antologin diskuterar den rättsliga regleringen av näringsdrivande stiftelser i åtta länder.