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BACKGROUND: Moderate differences in efficacy between adjuvant chemotherapy regimens for breast cancer are plausible, and could affect treatment choices. We sought any such differences.METHODS: We undertook individual-patient-data meta-analyses of the randomised trials comparing: any taxane-plus-anthracycline-based regimen versus the same, or more, non-taxane chemotherapy (n=44,000); one anthracycl

BACKGROUND: After breast-conserving surgery, radiotherapy reduces recurrence and breast cancer death, but it may do so more for some groups of women than for others. We describe the absolute magnitude of these reductions according to various prognostic and other patient characteristics, and relate the absolute reduction in 15-year risk of breast cancer death to the absolute reduction in 10-year re

This thesis assesses, through self-reflective practice, how the instruments of the tuba family have functioned as interfaces between composers and performers from the earliest records to the present day. A lack of knowledge surrounding the instruments and their capabilities and limitations has persisted since they were first employed by composers in the late seventeenth century, which suggests tha

In this study, we aimed to provide novel evidence on the impact of changing lifestyle habits on cancer risk. In the EPIC cohort, 295,865 middle-aged participants returned a lifestyle questionnaire at baseline and during follow-up. At both timepoints, we calculated a healthy lifestyle index (HLI) score based on cigarette smoking, alcohol consumption, body mass index and physical activity. HLI range

Within the new generation of structural materials having heterogeneous microarchitectures, one of the top performers is harmonic structure (HS). Herewith, the exciting discovery of self-similarity in their stress–strain behavior is reported. HS materials consist of the 3D skeleton of ultrafine grains (UFG) encompassing coarse-grained (CG) counterparts. Our discovery simplifies the mathematical des

I den här avhandlingen, syftar jag till att utforska kopplingarna mellan natur, konflikt och fred som bygger på litteratur från freds- och konflikstudier och miljöfredsbyggande. Jag hävdar att miljöfrågor, särskilt relaterade till fördelningen av naturresurser, är centrala för att förstå strukturella förhållanden möjliggör både konflikt och fred. För att svara på förskningsfrågan utforskar jag hurIn this dissertation, I aim to explore the links between nature, conflict, and peace building on literature from peace and conflict studies and environmental peacebuilding. I argue that environmental issues, especially related to the distribution of natural resources, are central to understanding structural conditions allowing for both conflict and peace. In order to answer the research question,

Increased concern was raised globally at the outbreak of COVID-19 that victims of domestic violence would be even more at risk when isolated with a violent partner and out of reach of support due to restrictions. Swedish staff in violence against women services prepared for increased calls for help. Instead, a worrying silence arose in a time and place of high uncertainty. This paper analyses the

Diabetes mellitus (DM) is a risk factor for the development of ulnar nerve entrapment (UNE). Differences in surgical outcomes for UNE between patients with and without DM have been reported, but studies on presurgical management are scarce. This study aimed to evaluate the presurgical management of UNE in patients with (DM diagnosis < 2 years of UNE diagnosis) and without DM regarding the level of

Firms compete on price and quality, but can also compete on issues of inclusion and sustainability, including gender and design as a competitive strategy. To develop a company brand that projects an image of an inclusive organization is one strategy that businesses can deploy to develop a unique selling proposition. Another possibility is to adapt product designs to include more groups within a po

This article explores work clothes as a site for negotiations of gender in relation to expertise in retail. Pointing to the importance of studying dress for the understanding of contemporary labor processes, the purpose of the article is to understand cultural and gendered meanings of work clothes by analyzing how workers handle expectations of their appearances. Based on qualitative methods and i

Den här boken handlar om hur växter, trädgårdar och trädgårdshantverk i vår tid görs till kulturarv och tar plats på marknader av olika slag. Här pågår ett ständigt prövande av vad som i olika avseenden betraktas som vitalt nog, appellerar till aktuella trender, har tillräckligt intresseväckande namn eller på annat sätt är gångbart. Utifrån en rad exempel på kulturarvsträdgårdar och kulturarvsväxt

This project studies coordination between the courses given by Environmental and Energy Systems Studies (IMES). The existence of an improvement gap and the aims for the coordination work at IMES were identified. Several areas for coordination were identified and their prioritisation and which issues within them to start working with were studied. Important aspects for structuring the coordination

OBJECTIVE: Disease recurrence, particularly intravesical recurrence (IVR) after radical nephroureterectomy (RNU) for upper tract urothelial carcinoma (UTUC), is common. We investigated whether violations of onco-surgical principles before or during RNU, collectively referred to as surgical violation (SV), were associated with survival outcomes. Material and methods: Data from a consecutive series

Changes in rainfall patterns driven by climate change affect the transport of dissolved organic matter (DOM) and nutrients through runoff to freshwater systems. This presents challenges for drinking water providers. DOM, which is a heterogeneous mix of organic molecules, serves as a critical precursor for disinfection by-products (DBPs) which are associated with adverse health effects. Predicting