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Benchmarking of Standard-Cell Based Memories in the sub-VT Domain in 65-nm CMOS Technology

In this paper, standard-cell based memories (SCMs)are proposed as an alternative to full-custom sub-VT SRAM macros for ultra-low-power systems requiring small memory blocks. The energy per memory access as well as the maximum achievable throughput in the sub-VT domain of various SCM architectures are evaluated by means of a gate-level sub-VT characterization model, building on data extracted from

Implications of parameter uncertainty on option prices

Financial markets are complex processes where investors interact to set prices. We present a framework for option valuation under imperfect information, taking risk neutral parameter uncertainty into account. The framework is a direct generalization of the existing valuation methodology. Many investors base their decisions on mathematical models that have been calibrated to market prices. We argue

Estrogen regulates DNA synthesis in human gingival epithelial cells displaying strong estrogen receptor β immunoreactivity.

Nebel D, Bratthall G, Ekblad E, Norderyd O, Nilsson B-O. Estrogen regulates DNA synthesis in human gingival epithelial cells displaying strong estrogen receptor β immunoreactivity. J Periodont Res 2011; doi: 10.1111/j.1600-0765.2011.01382.x. © 2011 John Wiley & Sons A/S Background and Objective: Estrogen acts via estrogen receptor (ER) α and β. The expression pattern of ERs and their importanc

Tjernobylkatastrofen : apokalyps eller pånyttfödelse?

This article explores the different ways in which the nuclear catastrophe at the Chernobyl plant in 1986 is represented in selected films and novels produced and written since the fall of the Soviet Union in 1991. The most common way of imagining Chernobyl during this period is the apocalypse foreshadowing the collapse of the Soviet Union. However, it is also viewed as the catalyst for resurrectio

TGF-β signaling in the control of hematopoietic stem cells.

Blood is a tissue with high cellular turnover, and its production is a tightly orchestrated process that requires constant replenishment. All mature blood cells are generated from hematopoietic stem cells (HSCs), which are the self-renewing units that sustain life-long hematopoiesis. HSC behavior, such as self-renewal and quiescence, are regulated by a wide array of factors, including external sig

Separable Lyapunov functions for monotone systems: Constructions and limitations.

For monotone systems evolving on the positive orthant, two types of Lyapunov functions are considered: Sum- and max-separable Lyapunov functions. One can be written as a sum, the other as a maximum of functions of scalar arguments. Several constructive existence results for both types are given. Notably, one construction provides a max-separable Lyapunov function that is defined at least on an arb

Receiving Gifts for Sex in Moscow, Kyiv, and Minsk: A Compensated Dating Survey

‘Compensated dating’’ (CD) indicates the exchange of sexual intimacy for material compensation. This article investigates CD as receiving gifts for sex, such as luxuries, rent, travel, or monetary gifts. It proceeds by describing who engages in the practice and why, while comparing Russia with its cultural and linguistic neighbors, Ukraine and Belarus. A survey, which was answered by a representat

Meanings Turkish people perceive in everyday occupations: Factor structure of Turkish OVal-pd

Occupational value with predefined items scale is an originally 26-item Swedish tool used to assess values people find in their everyday doings. The present study validated this scale on a Turkish sample and described the values that Turks perceived in their daily doings. The participants included a convenience sample of 446 adults with mean age 26 (SD = 7.3). Initial item analysis followed by pri

Evolution of operations planning and control: from production to supply chains

The focus of operations planning and control for manufacturing firms has expanded successively over the last 50 years. New principles, techniques, and systems have emerged that have allowed for new approaches. The perspective for planning and control has expanded from internal production operations to supply chain operations linking suppliers, manufacturers, and customers. In this paper, we take a

Dynamic changes in dopamine neuron function after DNSP-11 treatment: Effects in vivo and increased ERK 1/2 phosphorylation in vitro.

Glial cell-line derived neurotrophic factor (GDNF) has demonstrated robust effects on dopamine (DA) neuron function and survival. A post-translational processing model of the human GDNF proprotein theorizes the formation of smaller, amidated peptide(s) from the proregion that exhibit neurobiological function, including an 11-amino-acid peptide named dopamine neuron stimulating peptide-11 (DNSP-11)

Storm water quality of first flush urban runoff in relation to different traffic characteristics

Storm water quality was monitored at four sites in a middle-sized Swedish town. The objective was to compare storm water pollution in the first flush storm water runoff between sites with different traffic intensities within a town. Flow proportional storm water runoff samples were collected. The samples were analyzed for suspended solids, conductivity, total nitrogen, total phosphorus, oil index,

Childhood socio-economic status, school failure and drug abuse: a Swedish national cohort study

Aim To investigate whether socio-economic status (SES) in childhood and school failure at 15 years of age predict illicit drug abuse in youth and young adulthood. Design setting and participantsRegister study in a Swedish national cohort born 1973-88 (n=1405763), followed from age 16 to 20-35 years. Cox regression analyses were used to calculate hazard ratios (HR) for any indication of drug abuse.

Photoelectron spectroscopy of unsupported bismuth clusters: Size related effects of metallic properties

Evolution of metallic properties of free and initially neutral nanoscale Bi clusters has been studied using synchrotron radiation excited photoelectron spectroscopy. The 4f and 5d core as well as the valence levels have been probed. The cross-level analysis indicates metallic properties in Bi clusters in the observed size range from 0.5 nm to 1.4 nm. The behavior of the core-level and valence bind

The relative influences of climate and volcanic activity on Holocene lake development inferred from a mountain lake in central Kamchatka

A sediment sequence was taken from a closed, high altitude lake (informal name Olive-backed Lake) in the central mountain range of Kamchatka, in the Russian Far East. The sequence was dated by radiocarbon and tephrochronology and used for multi-proxy analyses (chironomids, pollen, diatoms). Although the evolution of Beringian climate through the Holocene is primarily driven by global forcing mecha

On-Demand Delivery of Single DNA Molecules Using Nanopipets.

Understanding the behavioral properties of single molecules or larger scale populations interacting with single molecules is currently a hotly pursued topic in nanotechnology. This arises from the potential such techniques have in relation to applications such as targeted drug delivery, early stage detection of disease, and drug screening. Although label and label-free single molecule detection st

Effects of alpha 1-antitrypsin on endotoxin-induced lung inflammation in vivo

Previous in vitro experiments demonstrated that acute-phase protein, alpha 1-antitrypsin (AAT), could act either as an enhancer or as a suppressor of lipopolysaccharide (LPS)-induced cell activation depending on treatment time. Here we investigate how AAT regulates inflammatory responses in the short term when administrated post LPS challenge. Similar experimental setup was used both in vitro and

Dural administration of inflammatory soup or Complete Freund's Adjuvant induces activation and inflammatory response in the rat trigeminal ganglion.

Migraine is a painful disorder with a huge impact on individual and public health. We hypothesize that migraine pain originates from a central mechanism that results secondarily in hypersensitivity in peripheral afferents associated with the cerebral and cranial blood vessels. It has previously been shown that application of inflammatory or algesic substances onto the dura mater or chemical stimul

INITIAL INSIGHTS INTO THE STRUCTURE-ACTIVITY RELATIONSHIPS OF AVIAN DEFENSINS.

Numerous β-defensins have been identified in birds and the potential use of these peptides as alternatives to antibiotics has been proposed, in particular to fight antibiotic-resistant and zoonotic bacterial species. Little is known about the mechanism of antibacterial activity of avian β-defensins (AvBDs), and the present work was carried out to obtain initial insights into the involvement of str