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Between Nature and Modernity : Agroecology as an alternative development pathway: the case of Uganda

Jordbruksmodernisering har dramatiskt ökat tillgången till mat på global nivå, men till ett högt pris för miljön. Idag efterlyser många ett ’paradigmskifte’ i jordbruket, även flera stora mainstream-institutioner. Med ett skifte till vad? Under senare år har det synts en ökande tilltro till agroekologi, ett alternativ som syftar till att förstå och bedriva jordbruk som komplexa agroekosystem. FrånAgricultural modernization has massively increased global food supply, but at a high environmental cost. Today many are calling for an agricultural ‘paradigm shift’, including several mainstream institutions. But to what? In recent years, agroecology has gained credence as an alternative approach that seeks to understand and manage farms as complex agroecosystems. From a development perspective, i

MEPS as climate policy

Researchers from Sweden (IIIEE, Lund University) and the US (Enervee) have found that minimum energy per-formance standards (MEPS) for home appliances are an effective alternative to stand-alone carbon pricing. A modest tightening of MEPS is already sufficient to account for climate externalities. For several appliances, carbon prices would have to increase manifold to provide the same incentives

From understanding to realizing novel III-Sb materials via nanowires

Due to their unique physical and material properties, III-Sb nanowires are considered good candidates for future devices, and test beds for understanding fundamental physics. Synthesizing these nanowires however is associated with certain challenging aspects, which are generally not present for other III-V nanowires, demanding the need for in depth investigations. For instance, growing Au-seeded I

Amyloid-beta 1-40 is associated with alterations in NG2+ pericyte population ex vivo and in vitro

The population of brain pericytes, a cell type important for vessel stability and blood brain barrier function, has recently been shown altered in patients with Alzheimer's disease (AD). The underlying reason for this alteration is not fully understood, but progressive accumulation of the AD characteristic peptide amyloid-beta (Aβ) has been suggested as a potential culprit. In the current study, w

Interior design dilemmas in a shared room of silence.

This text sheds light on the delicate practice of including different religious as well as nonreligious expressions in a shared room. The effects of design decisions in a “room of silence” at a Swedish hospital are studied over a transitional period of renovation of the space. We observe the impact of materiality in the room’s establishment, renovation, and usage, and show how the room’s interior

No title

Till skillnad från Ulibarrí är Sender en väldigt känd författare. Båda träffades i USA efter att denne flydde från Francos diktatur. Den här artikeln handlar om båda författarnas skönlitterära produktion under Senders exilår i USA.

Improving prediction of heart transplantation outcome using deep learning techniques

The primary objective of this study is to compare the accuracy of two risk models, International Heart Transplantation Survival Algorithm (IHTSA), developed using deep learning technique, and Index for Mortality Prediction After Cardiac Transplantation (IMPACT), to predict survival after heart transplantation. Data from adult heart transplanted patients between January 1997 to December 2011 were c

Identification of LTV Dynamical Models with Smooth or Discontinuous Time Evolution by means of Convex Optimization

We establish a connection between trend filtering and system identification which results in a family of new identification methods for linear, time-varying (LTV) dynamical models based on convex optimization. We demonstrate how the design of the cost function promotes a model with either a continuous change in dynamics over time, or causes discontinuous changes in model coefficients occurring at

QM/MM free-energy perturbation and other methods to estimate ligand-binding affinities

Proteiner är en av människokroppens byggstenar och har en mängd viktiga ochnödvändiga biologiska funktioner genom att delta i kemiska reaktioner och processer.De flesta proteiner har en bindningsficka som styr proteinets biologiska funktiongenom bindning av andra molekyler. Denna biologiska funktion kan i vissa fallkopplas till ett sjukdomstillstånd. Organiska molekyler som binder starkt tillbindnExperimental drug discovery is very time-consuming, risky and comes at a huge cost, typically several billion USD per drug. Even though decades of experimental drug discovery have provided cures of many diseases, there are still diseases for which there is no effective drug available. If drug development could be performedby theoretical and computational methods it would be of great advantage to h

De novo synthesis of thiamine (vitamin B1) is the ancestral state in Plasmodium parasites – evidence from avian haemosporidians

Parasites often have reduced genomes as their own genes become redundant when utilizing their host as a source of metabolites, thus losing their own de novo production of metabolites. Primate malaria parasites can synthesize vitamin B1 (thiamine) de novo but rodent malaria and other genome-sequenced apicomplexans cannot, as the three essential genes responsible for this pathway are absent in their

Plasmodium parasites of birds have the most AT-rich genes of eukaryotes

The genomic architecture of organisms, including nucleotide composition, can be highly variable, even among closely-related species. To better understand the causes leading to structural variation in genomes, information on distinct and diverse genomic features is needed. Malaria parasites are known for encompassing a wide range of genomic GC-content and it has long been thought that Plasmodium fa