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Two signals are required for induction of cell proliferation and cytokine production in resting T cells. Occupancy of the T cell receptor by antigen/MHC complexes delivers the first signal to the T cell, while the second signal is provided by interaction with costimulatory ligands on APC. CD2, LFA-1, and CD28 are the major costimulatory and adhesive molecules on T cells and bind to the LFA-3, ICAM
We analyze the origin of dramatic breakdown of diffractive factorization, observed in single-diffractive (SD) dijet production in hadronic collisions. One of the sources is the application of the results of measurements of the diagonal diffractive deep inelastic scattering to the off-diagonal hadronic diffractive process. The suppression caused by a possibility of inelastic interaction with the sp
Cardiac embolism is a common cause of ischemic stroke. Atrial fibrillation (AF) can be detected in nearly 25% of all patients with stroke by sequentially combining different electrocardiographic methods (1). Advanced IAB (aIAB) has been described to predict occurrence of new onset and recurrent AF (2). We describe a case of a patient in whom detection of atypical aIAB motivated extended cardiac mo
The Integrated Carbon Observation System Research Infrastructure aims to provide long-Term, continuous observations of sources and sinks of greenhouse gases such as carbon dioxide, methane, nitrous oxide, and water vapour. At ICOS ecosystem stations, the principal technique for measurements of ecosystem-Atmosphere exchange of GHGs is the eddy-covariance technique. The establishment and setup of an
Commercially available fast-response analysers for methane (CH4) and nitrous oxide (N2O) have recently become more sensitive, more robust and easier to operate. This has made their application for long-Term flux measurements with the eddy-covariance method more feasible. Unlike for carbon dioxide (CO2) and water vapour (H2O), there have so far been no guidelines on how to optimise and standardise
Research infrastructures play a key role in launching a new generation of integrated long-Term, geographically distributed observation programmes designed to monitor climate change, better understand its impacts on global ecosystems, and evaluate possible mitigation and adaptation strategies. The pan-European Integrated Carbon Observation System combines carbon and greenhouse gas (GHG; CO2, CH4, N
Local agri-environmental schemes, including hedgerows, flowering strips, organic management, and a landscape rich in semi-natural habitat patches, are assumed to enhance the presence of beneficial arthropods and their contribution to biological control in fruit crops. We studied the influence of local factors (orchard management and adjacent habitats) and of landscape composition on the abundance
Higgs boson production cross-sections in proton–proton collisions are measured in the H→WW⁎→eνμν decay channel. The proton–proton collision data were produced at the Large Hadron Collider at a centre-of-mass energy of 13 TeV and recorded by the ATLAS detector in 2015 and 2016, corresponding to an integrated luminosity of 36.1fb−1. The product of the H→WW⁎ branching fraction times the gluon–gluon f
The Mkoji sub-catchment is the most populated sub-catchment in the uppermost part of the Rufiji basin in Tanzania, with critical users downstream, and it is vulnerable to water shortages. Despite the efforts made by governmental and non-governmental organizations in forming and supporting water user associations, little is known about their role on water resource management in the country. This st
Development of mobile phone game. To make science available and fun for a wider audience.
We demonstrate the complete temporal characterization of the optical waveform of visible near-infrared octave-spanning ultrashort laser pulses, using an all-optical, all-solid-state, and fully inline dispersion-scan device based only on second-harmonic generation.
Active mode (walking, bicycling, and their variants) users are exposed to various negative externalities from motor vehicle traffic, including injury risks, noise, and air pollutants. This directly harms the users of these modes and discourages their use, creating a self-reinforcing cycle of less active travel, more motorized travel, and more harmful effects. These impacts are widely recognized bu
Aerotaxy, a recently invented aerosol-based growth method for nanostructures, has been shown to hold great promise in making III-V nanowires more accessible for cheap mass-production. Aerotaxy nanowire surface structure and chemistry, however, remains unexplored, which is unfortunate since this can influence (opto)electronic properties. We investigate the surfaces of aerotaxy grown GaAs nanowires
Background: Head and Neck Squamous Cell Carcinoma (HNSCC) tumors are often resistant to therapies. Therefore searching for predictive markers and new targets for treatment in clinically relevant in vitro tumor models is essential. Five HNSCC-derived cell lines were used to assess the effect of 3D culturing compared to 2D monolayers in terms of cell proliferation, response to anti-cancer therapy as
Background: A sizeable body of evidence suggests that statins can cease breast cancer progression and prevent breast cancer recurrence. The latest studies have, however, not been supportive of such clinically beneficial effects. These discrepancies may be explained by insufficient power. This considerably sized study investigates the association between both pre- and post-diagnostic statin use and
Background: In many European countries, women have a higher sickness absence rate than men. Women also report higher levels of work-life conflict, which has a negative impact on women's self-perceived health. Interventions studies on work-life balance literature are scarce. This research adds knowledge about work-life balance by examining female employees' experiences of a newly developed interven
Background: In the standard ECG display, limb leads are presented in a non-anatomical sequence: I, II, III, aVR, aVL, aVF. The Cabrera system is a display format which instead presents the limb leads in a cranial/left-to-caudal/right sequence, i.e. in an anatomically sequential order. Lead aVR is replaced in the Cabrera display by its inverted version, -aVR, which is presented in its logical place
Historisk genomgång av de lokaler som sedan 1600-talet hyst Lunds universitets ledning och förvaltning samt även kortfattad beskrivning av förvaltningsapparatens utveckling.
