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Functional outcome 3 months after stroke predicts long-term survival

Background: When reporting stroke survival and prognostic factors with a possible effect on outcome, the starting point for the observation of a clinical cohort usually is the onset of stroke or the acute admission of a patient. Thus, acute and early mortality inflict prognosis on long-term outcome. In order to give a more robust analysis of long-term survival after the acute period we chose to st

Management of patients with polycythaemia vera: results of a survey among Swedish haematologists

The prevailing attitudes regarding diagnostic and therapeutic procedures in patients with polycythaemia vera (PV) among Swedish haematologists were surveyed by way of a mailed questionnaire in August 2002. Among diagnostic procedures frequent use is reported for arterial O-2 saturation, spleen size determination, bone marrow histology, serum erythropoietin, serum cobalamins and leukocyte alkaline

Effects of long-term clarithromycin treatment on lavage-fluid markers of inflammation in chronic rhinosinusitis

Macrolides can be clinically effective in chronic rhinosinusitis (CRS). However, little is known about how these drugs affect pathophysiological features of CRS in vivo. In the present study, patients with CRS were subjected to long-term treatment with clarithromycin. Nasal lavages with and without histamine (40 and 400 mu g ml(-1)) were carried out prior to and late into the treatment period. His

Proteoglycans and hyaluronan in human fetal membranes

OBJECTIVE: The aim of this study was to describe the distributions of major extracellular matrix components, such as proteoglycans, collagen acid hyaluronan, in the fetal membranes at term. STUDY DESIGN: Fetal membranes were obtained from elective cesarean deliveries at term. Guanidinium extracts were analyzed for proteoglycans with alcian blue precipitation, sodium dodecyl sulfate-polyacrylamide

Standardization of diagnostic PCR for the detection of foodborne pathogens.

In vitro amplification of nucleic acids using the polymerase chain reaction (PCR) has become, since its discovery in the 1980s, a powerful diagnostic tool for the analysis of microbial infections as well as for the analysis of microorganisms in food samples. However, despite its potential, PCR has neither gained wide acceptance in routine diagnostics nor been widely incorporated in standardized me

Recrystallisation behaviour of native and processed waxy maize starch in relation to the molecular characteristics

Molecular characteristics were determined for native waxy maize starch and maize starch modified in different way (by mechanical treatment or/and acid hydrolysis). Recrystallisation behaviour was studied. Methods used in this study were MALLS, HPAEC-PAD, NMR, DSC, SEM, light microscopy. Five starch materials were subjected to storage under the same conditions in the presence of water (70 w/w%). Mo

Rapid decarbonisation of cities by addressing behavioural failures? A critical review of policy interventions

While many of the interventions to reduce carbon emissions target market failures, little attention is given to behavioural failures. This study investigates to what degree cities, which have taken a central role in global decarbonisation efforts, already incorporate findings from behavioural economics in their policy interventions. The ‘traditional taxonomy’ for policy intervention, represented a

Gnostiker som antikens feminister? : kvinnans roll och bilden av det feminina i antik gnosticism

In this article the notion that women retained a special position among ”Gnostics”, compared the surrounding context, is questioned. It is pointed out that there are no necessary correlation between myth and social reality. Finally, it is argued that proto-orthodox portrayals of “Gnostics” as favoring women should chiefly be under-stood as a polemical technique meant to discredit ones opponents.

Uncovering symmetries in polynomial systems

In this paper we study symmetries in polynomial equation systems and how they can be integrated into the action matrix method. The main contribution is a generalization of the partial p-fold symmetry and we provide new theoretical insights as to why these methods work. We show several examples of how to use this symmetry to construct more compact polynomial solvers. As a second contribution we pre

Catalytic Formation of Disulfide Bonds in Peptides by Molecularly Imprinted Microgels at Oil/Water Interfaces

This work describes the preparation and investigation of molecularly imprinted polymer (MIP) microgels (MGs) stabilized Pickering emulsions (PE) for their ability to catalyze the formation of disulfide bonds in peptides at the O/W interface. The MIP MGs were synthesized via precipitation polymerization and a programmed initiator change strategy. The MIP MGs were characterized using DLS analysis, S

Niche separation of pollen beetle parasitoids

Species with similar resource requirements are commonly assumed to competitively exclude each other, unless they differentiate their ecological niches. Hence, parasitoid wasps that use the same host species need to find some way to avoid competition. The aim of this study was to identify the role of volatile cues from oilseed rape plants and the larval host in niche separation between three coexis

The ethics of withdrawal : The case of follow-up from first-in-human clinical trials

This paper aims to analyze whether patients should be allowed to veto research-related use of medical data collected during routine follow-ups after their withdrawal from first-in-human clinical trials. Forms of withdrawal are identified and it is argued that the right to withdraw might be limited to some of these. The paper concludes that if veto right is denied, then: the research participant sh

The Role of Private Actors in Public Sector Innovation

The changing forms of governance stemming from the rise of New Public Management (NPM) and New Public Governance (NPG) have brought about significant changes in the relationship between the public and private sectors (Christensen and Lægreid 2007; Torfing and Triantafillou 2013). Not only have we witnessed a gradual increase in the involvement of private actors in the provision of public services,

Mismatch repair gene mutation spectrum in the Swedish Lynch syndrome population

Lynch syndrome caused by constitutional mismatch-repair defects is one of the most common hereditary cancer syndromes with a high risk for colorectal, endometrial, ovarian and urothelial cancer. Lynch syndrome is caused by mutations in the mismatch repair (MMR) genes i.e., MLH1, MSH2, MSH6 and PMS2. After 20 years of genetic counseling and genetic testing for Lynch syndrome, we have compiled the m

Assessing regional progress towards a ‘Green Energy Economy’

This paper provides a regional, empirical analysis of policy portfolios that aim to contribute towards a ‘Green Energy Economy’ (GEE) transformation. Taking green economy policies and related indicators as the analytical framework, the study examines (i) the composition of policy portfolios promoting low-carbon energy technologies, (ii) short-term trends related to the GEE, (iii) long-term empiric

HITS/Transparens Slutrapport

Projektet HITS/Transparens utforskar hur frivillig användning av informations- och kommunikationsteknologi av privata aktörer kan förbättra informationstransparens i transport av farligt gods. Detta tillvägagångssätt skiljer sig från en lång rad projekt som sedan 80-talet haft ett centralt myndighetsperspektiv på informationshantering kring farligt gods. I linje med tidigare resultat inom forsknin

Extended Law of Corresponding States Applied to Solvent Isotope Effect on a Globular Protein

Investigating proteins with techniques such as NMR or neutron scattering frequently requires the partial or complete substitution of D2O for H2O as a solvent, often tacitly assuming that such a solvent substitution does not significantly alter the properties of the protein. Here, we report a systematic investigation of the solvent isotope effect on the phase diagram of the lens protein gamma B-cry