Background: WNT5A (-/-) mammary tissue has been shown to exhibit increased ductal elongation, suggesting elevated mammary cell migration. Increased epithelial cell migration/invasion has often but not always been linked to the epithelial-mesenchymal transition (EMT). In the current study, we investigated the loss of WNT5A in HB2 human mammary epithelial cells and hypothesized that this loss increa

There is sufficient evidence that statins have a protective role against breast cancer proliferation and recurrence, but treatment predictive biomarkers are lacking. Breast cancer cell lines displaying diverse sensitivity to atorvastatin were subjected to global transcriptional profiling and genes significantly altered by statin treatment were identified. Atorvastatin treatment strongly inhibited

As a by-product of a meeting between my university’s vice-chancellor and the manager of the largest bank in the small southern town of Ystad in 2006, I, almost accidentally, soon after came to commence teaching and researching media production, production studies, media industries studies or film and media industry studies, as the subject finally came to be called at Lund. The teaching part involv

Background: Pulse wave velocity (PWV) is a biomarker for arterial stiffness, clinically assessed by applanation tonometry (AT). Increased use of phase-contrast cardiac magnetic resonance (CMR) imaging allows for PWV assessment with minor routine protocol additions. The aims were to investigate the acquired temporal resolution needed for accurate and precise measurements of CMR-PWV, and develop a t

Background. Patients use self-care to relieve symptoms of common colds, yet little is known about the prevalence and patterns across Europe. Methods/Design. In a cross-sectional study 27 primary care practices from 14 countries distributed 120 questionnaires to consecutive patients (≥18 years, any reason for consultation). A 27-item questionnaire asked for patients' self-care for their last common

Latent autoimmune diabetes of the adults (LADA) accounts for up to 12% of all patients with diabetes. Initially the disease resembles type 2 diabetes (T2D); however, the typical presence of β cell autoantibodies indicates an autoimmune basis of LADA. While dysfunctional regulatory T cells (Tregs) have been implicated in autoimmune diabetes, these cells have been scarcely studied in LADA. The aim o

We have synthesized and evaluated in tissue phantom measurements a new type of Nd-codoped upconverting nanoparticles. They provide improved signal strengths from deep regions in a tissue phantom as compared to conventional upconverting nanoparticles, a result also suggesting they will provide less issues with heating the tissue during measurements.

Whereas existing business models for sustainability research have mainly focused on business model activities and sustainability outcomes for separate firms, we observe that alliances between small and large firms can influence a large firm's learning and dissemination of sustainable technologies, thereby contributing to the sustainable transformation of mass markets. According to the theoretical

The experiment aims to assess the tryptophan content of main cultivars of naked oat in China, and analyze the correlation between contents of tryptophan and protein. Oat flour was hydrolysed with papain, the fluorescence intensity of hydrolysate was detected at excitation wavelength of 288 nm and emission wavelength of 352 nm, and finally the tryptophan content was quantitated according to standar

Blood transfusion is a clinically significant and crucial process, which saves millions of lives every year. However,shortage of donated blood and the risk of virus transmission through transfusible blood seriously affect theavailability of the blood. Hemoglobin (Hb), owing to its oxygen carrying capacity, has been studied as a startingmaterial for the development of artificial blood substitutes/H

Baker’s yeast, Saccharomyces cerevisiae, is a promising cell factory for the sustainable utilization of renewable resources for the formation of products with commercial value. Among these, poly-3-D-hydroxybutyrate (PHB) is an extensively studied biopolymer naturally accumulated in some bacteria and archaea species through the formation of carbon granules. Its bio-based origin, biodegradability an

The main purpose of this study was to compare two non-invasive optical spectroscopic techniques for assessing peripheral oxygenation saturation in healthy volunteers under specific provocations. The results suggest that the time-resolved technique provides more accurate and robust results.

This paper brings forward a service oriented perspective, based on practical experiences from designing information systems (IS) as services. Viewing IS as services are beneficial but still an unexplored approach in organizations. In this paper, we present an analysis of Enterprise Resource Planning (ERPs) systems through the perspective of Service Oriented Architecture (SOA). This paper contribut

The main purpose of this study was to investigate a novel non-invasive optical technique for rapid bedside detection of oxygen gas in the lungs of full-term newborn infants. The results suggest that the technique will be clinically useful as a diagnostic and monitoring tool for infants with lung disorders.

We study upscaling of gas high harmonic generation, to make efficient use of the ever increasing laser pulse powers. Loose focusing geometries optimizing phasematching are investigated and compared in HHG efficiency to shorter focusing arrangements.

Extrapolating nonlinear phenomena, such as filamentation, to new parameters as e.g. to higher pulse energy is often challenging. We here present a general scaling model for nonlinear light-matter interactions in gases and proof it experimentally.

The heat recovery system for ventilation is of major importance when low energy buildings are built. One alternative to the mechanical ventilation systems with heat recovery is to use a brine based run-around system that allows for heat recovery in for instance hybrid ventilated buildings. This type of heat recovery system has the potential to lower the need for electricity for the fans. Also, theThe heat recovery system for ventilation is of major importance when low energy buildings are built. One alternative to the mechanical ventilation systems with heat recovery is to use a brine based run-around system that allows for heat recovery in for instance hybrid ventilated buildings. This type of heat recovery system has the potential to lower the need for electricity for the fans. Also, the