Sökresultat

Filtyp

Din sökning på "*" gav 530640 sökträffar

Possible roles of reactive chlorine II: assessing biotic chlorination as a way for organisms to handle oxygen stress.

Natural formation of organically bound chlorine is extensive in many environments. The enzymes associated with the formation of chlorinated organic matter are produced by a large variety of organisms. Little is known about the ecological role of the process, the key question being: why do microorganisms promote chlorination of organic matter? In a recent paper we discuss whether organic matter chl

Plant–soil feedbacks of exotic plant species across life forms: a meta-analysis

Invasive exotic plant species effects on soil biota and processes in their new range can promote or counteract invasions via changed plant–soil feedback interactions to themselves or to native plant species. Recent meta-analyses reveale that soil influenced by native and exotic plant species is affecting growth and performance of natives more strongly than exotics. However, the question is how uni

Priority effects in a planktonic bloom-forming marine diatom

Priority effects occur when a species or genotype with earlier arrival has an advantage such that its relative abundance in the community or population is increased compared with later-arriving species. Few studies have dealt with this concept in the context of within-species competition. Skeletonema marinoi is a marine diatom that shows a high degree of genetic differentiation between populations

The importance of work organization on workload and musculoskeletal health - Grocery store work as a model.

We have evaluated the consequences of work organization on musculoskeletal health. Using a postal questionnaire, answered by 1600 female grocery store workers, their main work tasks were identified and four work groups were defined (cashier, picking, and delicatessen work, and a mixed group, who performed a mix of these tasks). The crude odds ratios (ORs) for neck/shoulder complaints were 1.5 (95%

Treatment with the sphingosine-1-phosphate analogue FTY 720 reduces loss of plasma volume during experimental sepsis in the rat.

BACKGROUND: Increased vascular leakage leading to hypovolaemia and tissue oedema is common in severe sepsis. Hypovolaemia together with oedema formation may contribute to hypoxia and result in multiorgan failure and death. To improve treatment during sepsis, a potential therapeutic target may be to reduce the vascular leakage. Substances affecting the endothelial barrier are interesting in this re

Adult weight change and risk of colorectal cancer in the European Prospective Investigation into Cancer and Nutrition

Aim: Weight change during adult life may reflect metabolic changes and influence colorectal cancer (CRC) development, but such role is not well established. We aimed to explore the association between adult weight change (from age 20 to 50) and CRC risk. In particular, we investigated differences according to colon and rectal cancer, sex and measures of attained adiposity. Methods: We included 201

Identification of fibroblast growth factor-8b target genes associated with early and late cell cycle events in breast cancer cells.

Fibroblast growth factor-8 (FGF-8) is implicated in the development and progression of breast cancer and its levels are frequently elevated in breast tumors. The mechanisms driving FGF-8-mediated tumorigenesis are not well understood. Herein we aimed to identify target genes associated with FGF-8b-mediated breast cancer cell proliferation by carrying out a cDNA microarray analysis of genes express

Use of synchrotron-radiation-based FTIR imaging for characterizing changes in cell contents

FTIR imaging of individual cells is still limited by the low signal-to-noise ratio obtained from analysis of such weakly absorbing organic matter when using a Globar IR source. In this study, we used FTIR imaging with a synchrotron radiation source and a focal plane array detector to determine changes in the cellular contents of cryofixed cells after culture for 48 h on Si3N4 substrate. Several sp

Does Imaging Modality Used for Percutaneous Renal Access Make a Difference? A Matched Case Analysis

Objective: To assess perioperative outcomes of percutaneous nephrolithotomy (PCNL) using ultrasound or fluoroscopic guidance for percutaneous access. Methods: A prospectively collected international Clinical Research Office of the Endourological Society (CROES) database containing 5806 patients treated with PCNL was used for the study. Patients were divided into two groups based on the methods of

Poll of polls: A compositional loess model

A large number of polls on party preferences are published today. In order to get an estimate of the changes in political opinion, the polls may be combined into a poll of polls. We discuss a method for combining polls using the fact that they are compositions and respecting the properties of the compositional sample space (the simplex). The method is easily implemented and the estimate may be com

Ghosts from the past - ancestral features reflected in the jaw ontogeny of the polychaetous annelids Marphysa fauchaldi (Eunicidae) and Diopatra aciculata (Onuphidae)

Species of Eunicida (polychaetous annelids) have complex jaw apparatuses with ventral mandibles growing throughout life, but dorsal maxillae undergoing successive moulting episodes. Jaw ontogeny was studied in the eunicid Marphysa fauchaldi, from the appearance of the mandibles and larval maxillae through two moults during the transformation to juvenile and sub-adult maxillae. Although larval maxi

Influence of microporosity in SBA-15 on the release properties of anticancer drug dasatinib

The release of the hydrophobic cancer drug dasatinib from two mesoporous silica materials as drug delivery vehicles has been studied. One material is a reference 2D-hexagonal SBA-15 with the typical bimodal pore system with ordered primary mesopores and disordered intrawatI pores. The other material is a modified version of the same material where the intrawall porosity in the micropore regime has

A mouse model of mitochondrial complex III dysfunction induced by myxothiazol.

Myxothiazol is a respiratory chain complex III (CIII) inhibitor that binds to the ubiquinol oxidation site Qo of CIII. It blocks electron transfer from ubiquinol to cytochrome b and thus inhibits CIII activity. It has been utilized as a tool in studies of respiratory chain function in in vitro and cell culture models. We developed a mouse model of biochemically induced and reversible CIII inhibiti

Regeneration in, and properties of, extracted peripheral nerve allografts and xenografts.

Abstract When not enough conventional autologous nerve grafts are available, alternatives are needed to bridge nerve defects. Our aim was to study regeneration of nerves in chemically-extracted acellular nerve grafts from frogs, mice, humans (fresh and stored sural nerve), pigs and rats when defects in rat sciatic nerves were bridged. Secondly, we compared two different extraction procedures (tech

Prevention of falls in the elderly: A review.

Aims: Falls often result in soft tissue injuries, dislocations, fractures, longstanding pain and reduced quality of life. Therefore, fall preventive programmes have been developed. Methods: In this review, we evaluate programmes that in randomized controlled trials (RCT) have been shown with fall reducing effect. Results: Physical exercise that includes several training modalities, especially bala

Narrative skills in Swedish children with language impairment

This study investigated the development of narrative skills in Swedish children with language impairment between age 5 and age 10. Seventeen children with LI and two control groups of age peers with typical development participated in a picture elicited story telling task. Analyses included measures of story content, cohesion and grammar. Our subjects showed development in different areas from age

Gate-defined double quantum dot with integrated charge sensors realized in InGaAs/InP by incorporating a high-kappa dielectric

A gate-defined double quantum dot with two integrated quantum point contact charge sensors is realized in an InGaAs/InP heterostructure by employing a high-kappa HfO2 thin film as gate dielectric and a polymer bridge technique. Clear honeycomb patterns are observed in the measured charge stability diagram of the double quantum dot and charge sensing signals of the quantum point contacts. It is als

The Influence of Physical Environmental Qualities on the Social Climate of Supported Housing Facilities for People with Severe Mental Illness.

The study investigates the extent to which the perceived physical environmental quality of housing facilities for people with severe mental illness accounts for perceived social environmental quality. Twenty facilities were assessed by people with psychiatric disabilities (residents), staff, and experts with regard to the physical environmental aspects of visual pleasantness, indirect environmenta

U-Pb ages and geochemistry of mafic dyke swarms from the Uaua Block, Sao Francisco Craton, Brazil: LIPs remnants relevant for Late Archaean break-up of a supercraton

The Sao Francisco Craton (SFC) is an Archaean craton that hosts a significant number of mafic intrusions. Previous attempts to date the igneous emplacement of these rocks are limited to a few dates of poor precision. Here, two dyke swarms from the Uaua Block in the northeastern portion of the craton were dated using U-Pb on baddeleyite (ID-TIMS) and zircon (SIMS). The older dyke swarm trends mainl