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The Concept of Urban Hibernation

Today, as a result of fast-paced societal transformations, many small towns face severe developmental challenges and an uncertain future. Departing from the broader theory of developmental disequilibrium, we launch the concept of urban hibernation to explain the process of periodic small-town regress. The concept—along with its key stages and turning points—is presented to the background of urbani

Innovation and Public Procurement. Review of Issues at Stake

The use of public demand to spur innovation has recently seen a very significant in-crease in political support. Such a policy promises improvement of public services on all state levels, combined with a contribution to innovation dynamics. It has become clear that strong efforts are needed to mobilise procurement at all state levels for inno-vative markets. These efforts need to be based on a bet

Cities and Regions in the New Learning Economy

The process of transforming the industrial economy into a society largely based on the production and dissemination of information and knowledge has widespread implications for cities and regions as well as organisations and individuals. And while the economy is increasingly global, the differences in economic development between cities and regions will not necessarily disappear. Indeed, the diver

Public Technology Procurement and Innovation

Public Technology Procurement and Innovation studies public technology procurement as an instrument of innovation policy. In the past few years, public technology procurement has been a relatively neglected topic in the theoretical and research literature on the economics of innovation. Similarly, preoccupation with `supply-side' measures has led policy-makers to avoid making very extensive use of

Low Temperature Waste Heat Recovery in Internal Combustion Engines

Over the past few decades, the automotive industry has increasingly looked towards increasing the efficiency of the internal combustion engine to meet more stringent emission norms and as a measure to meet demands for improved air quality in cities. One method to improve the internal combustion engine efficiency is to recover some of the energy lost to the coolant and the exhaust using a secondary

Gene expression of breast cancer related genes in circulating tumour cells (CTCs) from patients with metastatic breast cancer

Introduction: Detection of circulating tumour cells (CTCs) in peripheral blood has an established prognostic significance in patients with metastatic breast cancer. Change in the number of detected CTCs is also an indication of response to therapy. Characterisation of CTCs could provide easily accessible treatment predictive information of present cancer cells within the patient and could reveal i

Attention and multisensory integration of emotions in schizophrenia

The impairment of multisensory integration in schizophrenia is often explained by deficits of attentional selection. Emotion perception, however, does not always depend on attention because affective stimuli can capture attention automatically. In our study, we specify the role of attention in the multisensory perception of emotional stimuli in schizophrenia. We evaluated attention by interference

Anti-smuggling and Anti-trafficking Measures: Are they compatible with the EU Charter of Fundamental Rights?

Combatting human smuggling and human trafficking has been one of the priority objectives of the EU and its Member States in their efforts to decrease the number of migrants arriving in EU territory. The development of strong cooperation with third-countries has been considered indispensable to the effectiveness of what is often described in EU documents as the ‘fight’ against human trafficking and

Inflammatory potential of the diet and risk of colorectal cancer in the European Prospective Investigation into Cancer and Nutrition study

Proinflammatory diets are associated with risk of developing colorectal cancer (CRC), however, inconsistencies exist in subsite- and sex-specific associations. The relationship between CRC and combined lifestyle-related factors that contribute toward a low-grade inflammatory profile has not yet been explored. We examined the association between the dietary inflammatory potential and an inflammator

Comparison of three methods to determine the degree of substitution of quinoa and rice starch acetates, propionates, and butyrates : Direct stoichiometry, FTIR, and 1H-NMR

Rice and quinoa starch esters were prepared by acylation using short-chain fatty acid anhydrides with different chain lengths (acetic, propionic, and butyric anhydride). A direct stoichiometric method based on the acylation reaction was used to determine the degree of substitution (DS) and acyl content (AC). In addition, Fourier-transform infrared spectroscopy (FTIR) was used to validate the confo

Growth pattern of experimental glioblastoma

Glioblastoma multiforme (GBM) is an aggressive primary brain malignancy with a very poor prognosis. Researchers employ animal models to develop potential therapies. It is important that these models have clinical relevance. This means that old models, propagated for decades in cultures, should be questioned. Parameters to be evaluated include whether animals are immune competent or not, the infilt