Open access har till största delen handlat om att göra vetenskapliga tidskriftsartiklar fritt tillgängliga. Under senare år har allt flera initiativ som fokuserar på den vetenskapliga monografin kommit fram. Allt flera ser affärsmodellen för tryckta monografier inom humaniora och samhällsvetenskap som ohållbar och förlag, universitet och andra aktörer letar efter nya vägar för monografin. Den här

Background: Animal migration requires adaptations in morphological, physiological and behavioural traits. Several of these traits have been shown to possess a strong heritable component in birds, but little is known about their genetic architecture. Here we used 454 sequencing of brain-derived transcriptomes from two differentially migrating subspecies of the willow warbler Phylloscopus trochilus

Previous research has suggested that there is a relationship between the three key components of Donabedian's conceptual model for quality assessments: structure of care, process, and outcome of care. That is, structure predicted both process and outcome of care, and better processes predict better functional outcomes and user satisfaction. The results in this study involving samples of Danish and

The sharpness and thus information content of the retinal image in the eye depends on the optical quality of the lens and its accurate positioning in the eye. Multifocal lenses create well-focused color images and are present in the eyes of all vertebrate groups studied to date (mammals, reptiles including birds, amphibians, and ray-finned fishes) and occur even in lampreys, i.e., the most basal v

A complex of chagasin, a protein inhibitor from Trypanosoma cruzi, and papain, a classic family C1 cysteine protease, has been crystallized. Kinetic studies revealed that inactivation of papain by chagasin is very fast (k(on) = 1.5 x 10(6) m(-1).s(-1)), and results in the formation of a very tight, reversible complex (K-i = 36 pm), with similar or better rate and equilibrium constants than those f

The ATLAS TRT end-cap is a tracking drift chamber using 245,760 individual tubular drift tubes. It is a part of the TRT tracker which consist of the barrel and two end-caps. The TRT end-caps cover the forward and backward pseudo-rapidity region 1.0 < vertical bar eta vertical bar < 2.0, while the TRT barrel central eta region vertical bar eta vertical bar < 1.0. The TRT system provides a combinati

Objective: To describe dietary protein intakes and their food sources among 27 redefined centres in 10 countries participating in the European Prospective Investigation into Cancer and Nutrition (EPIC). Methods: Between 1995 and 2000, 36 034 persons, aged between 35 and 74 years, were administered a standardized 24-h dietary recall (24-HDR) using a computerized interview software programme (EPIC-S

We present a Monte Carlo algorithm for Hamiltonicity detection in an $n$-vertex undirected graph running in $O(1.657^{n})$ time. To the best of our knowledge, this is the first superpolynomial improvement on the worst case runtime for the problem since the $O^*(2^n)$ bound established for the traveling salesman problem (TSP) over 50 years ago [R. Bellman, J. Assoc. Comput. Mach., 9 (1962), pp. 61-

The medium-induced one-gluon radiation spectrum off a massive quark-antiquark (q (q) over bar) antenna traversing a colored QCD medium is calculated in this contribution. The gluon spectrum off the antenna computed at first order in the opacity expansion is collinear finite but infrared divergent, which is different from the result obtained from an independent emitter which is both infrared and co

Background: To ensure a correct interpretation of results obtained with quantitative real-time reverse transcription-polymerase chain reaction (RT-qPCR), it is critical to normalize to a reference gene with stable mRNA expression in the tissue of interest. GADPH is widely used as a reference gene in ovarian tumour studies, although lacking tissue-specific stability. The aim of this study was to id

Estimating temporal trends in spatially structured populations has a critical role to play in understanding regional changes in biological populations and developing management strategies. Designing effective monitoring programmes to estimate these trends requires important decisions to be made about how to allocate sampling effort among spatial replicates (i.e. number of sites) and temporal repli

A structural characterization of mixed micelles formed in aqueous solution by the PEO-PPO-PEO triblock copolymer P123 and the nonionic surfactant C(12)EO(6) was carried out using various techniques, including ultralow shear viscosimetry, depolarized dynamic light scattering (VH-DLS), depolarized static light scattering (VH-SLS), and small-angle X-ray scattering (SAXS). The sphere-to-rod transition

Cancer-associated fibroblasts (CAF) stimulate tumor growth and metastasis. Signals supporting CAF function are thus emerging as candidate therapeutic targets in the tumor microenvironment. The chemokine CXCL14 is a potent inducer of CAF protumorigenic functions. This study is aimed at learning how the protumoral functions of CXCL14-expressing CAF are maintained. We found that the nitric oxide synt

A new approach for studying mixing and combustion phenomena in turbulent partially premixed flames using laser-induced breakdown spectroscopy (LIBS) is demonstrated. Setting the laser pulse energy just above the breakdown threshold in the cold gas allows statistical data to be obtained concerning the probability of finding cold or hot gas inside the measurement volume. Moreover, a compositional an

The nuclear factor κB (NF-κB) is a promising target for drug discovery. NF-κB is a heterodimeric complex of RelA and p50 subunits that interact with the DNA, regulating the expression of several genes; its dysregulation can trigger diverse diseases including inflammation, immunodeficiency, and cancer. There is some experimental evidence, based on whole cells studies, that natural sesquiterpene lac

Nowadays for small-scale power generation there are electrochemical batteries and mini engines. Many efforts have been done for improving the power density of the batteries but unfortunately the value of 1 MJ/kg seems to be asymptotic. If the energy source is an organic fuel which has an energy density of around 29 MJ/kg with a minimum overall efficiency of only 3.5%, this device would surpass the

The primary aim of the article is to examine the sum of the three Swedish judgments of 2013 that was handed down after the ECJ's judgment in the Åkerberg Fransson-case. The examination is done against the backdrop of the legal developments preceding these judgments, with a particular attention to how different layers of law are perceived and given effect in the national legal order.