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The K-Cl cotransporter in the lobster stretch receptor neurone-a kinetic analysis.

Experiments were performed to define quantitatively the substrate (K(+) and Cl(-)) dependence of the transport function (production of equally large and oppositely directed K(+)and Cl(-) flows/currents) of an earlier (Theander et al., 1999) identified electroneutral K-Cl cotransporter in the slowly adapting stretch receptor neurone of the European lobster. The experiments were based on microelectr

TRIM22/Staf50 - a novel target gene of the tumor suppressor p53

Popular Abstract in Swedish Skulle p53-målgenen TRIM22 kunna skydda mot cancer uppkomst? Frisk blodbildning En frisk vuxen människa har mellan fyra och sex liter blod, beroende på individens kroppsstorlek. Blodet produceras i benmärgen som finns i skelettbenen. Varje sekund bildas normalt i benmärgen tre till fyra miljoner blodkroppar från våra stamceller. Blodkropparna är specialiserade celler The tumor suppressor gene p53 is a transcription factor that mediates cell cycle arrest, apoptosis and differentiation. p53 mediated differentiation of leukemic cells depends on the transcriptional activity of p53 but so far no obvious differentiation inducing target gene has been identified. Using a cDNA microarray analysis, I identified TRIM22/Staf50 as a novel direct target gene to p53. The fun

Stability of voltage and frequency control in distributed generation based on parallel-connected converters feeding constant power loads

In this paper stability and dynamic properties of voltage and frequency droop control of power electronic converters are investigated for a distributed generation system. Droop control is utilized to share active and reactive power among the source converters. The voltage and frequency controllers are designed so that stand-alone converter operation feeding constant power loads performs satisfacto

Determination of protein diffusion coefficients in agarose gel with a diffusion cell

A diffusion cell has been used to measure the effective diffusion coefficients of proteins. The method is applied to lysozyme and BSA at different pH and ionic strength. A parameter optimization technique is used to estimate the diffusion coefficients directly from experimental data. The importance and influence of pH and ionic strength on the diffusive properties in an agarose gel have been demon

Modeling, Control and Optimization of a Plate Reactor

Popular Abstract in Swedish En ny typ av reaktor för kemikalie och läkemedelsproduktion är under utveckling av Alfa Laval AB, ett svenskt företag som är en världsledande tillverkare av värmeväxlare. Den nya reaktortypen, som kallas för plattreaktor, kombinerar den höga värmeöverföringsförmågan från plattvärmeväxlaren med den effektiva mikro-mixningen av kemikalier som är typisk för en mikro-reaktoA new chemical reactor, the Alfa Laval Plate Reactor, is being developed by Alfa Laval, a Swedish world-leading heat exchanger company. The plate reactor combines the high-heat-transfer capabilities of plate heat exchangers with the efficient mixing and reaction control typical of microreactors. With this new concept, highly exothermic reactions can be produced using more concentrated reactants an

Isospin effects on two-particle correlation functions in E/A=61 MeV Ar-36+Sn-112,Sn-124 reactions

Small-angle, two-particle correlation functions have been measured for Ar-36+Sn-112,Sn-124 collisions at E/A=61 MeV. Total momentum gated neutron-proton (np) and proton-proton (pp) correlations are stronger for the Sn-124 target. Some of the correlation functions for particle pairs involving deuterons or tritons (nd, pt, and nt) also show a dependence on the isospin of the emitting source.

Co on Mo(110) studied by scanning tunneling microscopy

We have studied the interface formation of thin films of Co on a Mo(1 1 0) surface by the use of scanning tunneling microscopy (STM), low energy electron diffraction (LEED) and auger electron spectroscopy (AES). Below a coverage of about 0.4 monolayers (ML) we find that Co grows in small islands which are pesudomorphic with the Mo substrate. At a Cc coverage above 0.4 ML, the Co atoms condense int

Evaluating simplifications used in regional applications of the SAFE and MAKEDEP models

The importance of different additional simplifications used when moving from single site applications to regional applications of the SAFE and MAKEDEP models was studied. The SAFE model is a dynamic soil chemistry model, which apart from physical and chemical soil parameters also needs the historic evolution of atmospheric deposition and nutrient uptake to simulate the effects of acidic deposition

Preventive Environmental Strategies in Eastern European Industry: An analysis of donor support for cleaner production

Popular Abstract in Swedish Östeuropeisk industri är ökänd både för sin miljöpåverkan och för sin besvärliga ekonomiska sits. Detta gör att resurserna som finns tillgängliga för miljöarbete är små - om dom finns överhuvudtaget. Den möjlighet som då återstår ligger i den förebyggande miljöskyddsstrategin där förbättringarna uppnås genom att gå in i produktionsprocesserna och effektivisera användninSince 1991 cleaner production projects have been pursued by the donors in Eastern European industry. These projects have aimed at demonstrating the benefits of a preventive approach to environmental protection, and to train people within the industry to perform the cleaner production assessments that constitute the core element of the preventive approach. The large merit of the preventive approach

Hydrogen peroxide production in ischaemic retina: influence of hyperglycaemia and postischaemic oxygen tension

Free radicals have recently been proposed to play a role in the development of diabetic retinopathy. Ischaemia and hyperglycaemia followed by recirculation have been suggested to initiate free radical production in other tissues and the aim of the present study was to examine whether this could also be the case in the retina. The present study showed retinal cell damage, as measured by pycnotic ce

Molecular characterization of the rhesus rhadinovirus (RRV) ORF4 gene and the RRV complement control protein it encodes

The diversity of viral strategies to modulate complement activation indicates that this component of the immune system has significant antiviral potential. One example is the Kaposi's sarcoma-associated herpesvirus (KSHV) complement control protein (KCP), which inhibits progression of the complement cascade. Rhesus rhadinovirus (RRV), like KSHV, is a member of the subfamily Gammaherpesvirinae and

Effect on cardiac contractile force from addition of cations and oxygen to iohexol. Comparison with other low-osmotic contrast media in the isolated rabbit heart during normal and reduced perfusion pressure

The coronary arteries of the isolated rabbit heart were perfused with different contrast media (CM). The effects on cardiac contractile force (CF) from enriching iohexol solutions with sodium, calcium, potassium, magnesium and oxygen were investigated. The effects were studied during normal and reduced perfusion pressure; the latter was intended to simulate flow conditions distal to proximal steno