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Cytogenetic aberrations and their prognostic impact in chondrosarcoma

Chondrosarcoma is the second most common primary malignancy of bone. Cytogenetic data are available from close to 100 cases, including all subtypes of chondrosarcoma. Specific chromosomal rearrangements have been identified only in extraskeletal myxoid chondrosarcoma (EMC). Strong prognostic factors are largely missing, although size and, in particular, histologic tumor grade have been implicated.

Effects of Supersaturation on the Crystal Structure of Gold Seeded III-V Nanowires

We present results that provide fundamental insights on how to experimentally tailor the planar defect density and even the crystal structure in III-V metal particle seeded nanowires, where zinc blende is the stable bulk crystal structure. We have grown GaP nanowires with metal-organic vapor phase epitaxy under different conditions: pulsing of the Ga source, and continuous growth with and without

Origins of substance P- and calcitonin gene-related peptide-containing nerves in the internal carotid artery of rat

An aggregation of substance P (SP)- and calcitonin gene-related peptide (CGRP)-containing nerve cells (internal carotid mini-ganglion) is described at the junction between the greater superficial petrosal nerve and the internal carotid nerve close to the internal carotid artery. A retrograde tracer dye technique demonstrates that this ganglion and the trigeminal and superior vagal ganglia supply t

The 5th annual European league against rheumatism congress in Berlin: A personal perspective

The 5th annual European League Against Rheumatism congress, held in Berlin, 9-12 June 2004, was attended by a record number of delegates from all continents and offered a large choice of education, state-of-the-art and original research presentations in up to 15 parallel sessions. Some of these were poorly attended, although featuring top-ranked abstracts. The poster sessions remain a problem chil

Psychiatric telephone interview with parents for screening of childhood autism - tics, attention-deficit hyperactivity disorder and other comorbidities (A-TAC): Preliminary reliability and validity.

Abstract in UndeterminedBackgroundReliable, valid and easily administered screening instruments would greatly facilitate large-scale neuropsychiatric research.Aims To test a parent telephone interview focused on autism – tics, attention-deficit hyperactivity disorder (ADHD) and other comorbidities (A–TAC).MethodParents of 84 children in contact with a child neuropsychiatric clinic and 27 control c

Use of immobilised lipase from Candida antarctica in supercritical fluid extraction of borage (Borago officinalis L.) seed oil

This study aims at the investigation of the possibilities to use immobilised lipase from Candida antarctica in supercritical fluid extraction (SFE) of borage (Borago officinalis L.) seed oil. The first series of experiments was performed to measure the extract yields obtained with pure CO2 and with the added entrainer (ethanol). The yield increased more than twice after increasing the extraction p

Mn diffusion in Ga1-xMnxAs/GaAs superlattices

Ga1-xMnxAs/GaAs superlattices with Mn concentrations of 1% and 5% in the Ga1-xMnxAs layers and a GaAs spacer thickness of 4 and 60 GaAs monolayers have been studied by cross-sectional scanning tunneling microscopy. By achieving atomic resolution of the superlattices, we observe individual Mn atoms in the Ga1-xMnxAs layers and in the GaAs spacer. We find that about 20% of the total amount of Mn dif

Haematopoietic progenitor cells utilise conventional PKC to suppress PKB/Akt activity in response to c-Kit stimulation

Receptor tyrosine kinase (RTK) c-Kit signalling is crucial for the proliferation, survival and differentiation of haematopoietic stem cells (HSCs). To further understand the mechanisms underlying these events we explored how the downstream mediators interact. The present study investigated the function of conventional protein kinase Cs (c-PKC) in c-Kit mediated signalling pathways in HSC-like cell

Forces between silica surfaces with adsorbed cationic surfactants: Influence of salt and added nonionic surfactants

Forces have been measured between silica surfaces with adsorbed surfactants by means of a bimorph surface force apparatus. The surfactants used are the cationic surfactant tetradecyltrimethylammonium bromide (TTAB) and the nonionic surfactant hexakis(ethylene glycol) mono-n-tetradecyl ether (C14E6) as well as mixtures of these two surfactants. The measurements were made at elevated pH, and the eff

Granulocyte-stimulating factor and severe aplastic anemia: a survey by the European Group for Blood and Marrow Transplantation (EBMT)

Previous studies suggested a link between the use of G-CSF and increased incidence of myelodysplastic syndrome (MDS) and acute myeloid leukemia (AML) after immunosuppressive therapy (IST) for severe aplastic anemia (SAA). This European survey included 840 patients who received a first-line IST with (43%) or without (57%) G-CSF. The incidences of MDS/AML in patients who did or did not receive G-CSF

Variations in the isotopic composition of molybdenum in freshwater lake systems

Variations in molybdenum isotopic composition, spanning the range of similar to 2.3 parts per thousand in the terms of Mo-97/Mo-95 ratio, have been measured in sediment cores from three lakes in northern Sweden and north-western Russia. These variations have been produced by both isotopically variable input of Mo into the lakes due to Mo isotopic heterogeneity of bedrock in the drainage basins and

Military expenditures in developing countries: a comment on Deger and Sen

This note contains a criticism of an article by Deger and Sen (1983) who discuss the causes of military expenditure in less developed countries. It is argued that their utility function is unsuitably specified and that the conclusions drawn may be called into question. Moreover, it is doubtful whether the concept of a benevolent government that maximizes a single utility function is conducive to a

Nondielectric long-range solvation of polar liquids in cubic symmetry

Long-range solvation properties of strongly coupled dipolar systems simulated using the Ewald and reaction field methods are assessed by using electric fluctuation formulas for a dielectric medium. Some components of the fluctuating electric multipole moments are suppressed, whereas other components are favored as the boundary of the simulation box is approached. An analysis of electrostatic inter

Monitoring for sustainable development : a systemic framework

'Sustainable development' is a widely used, but less practised, complex term. Using the idea of 'Viability Loops' (VL) based on a System Dynamics (SD) approach and considering sustainability as an ideal for development efforts, this paper argues that sustainable development should be considered as an unending process rather than a state. Thus, a systemic framework is proposed to 'monitor' systems

Large eddy simulations of turbulent swirling flows in a dump combustor: a sensitivity study

Large eddy simulations (LES) of confined turbulent swirling flows in a model dump combustor are carried out. The simulations are based on a high-order finite difference method on a Cartesian grid, with the sub-grid scale stress tensor modelled using a scale-similarity model. The aims of this work are to study the physics of the flow and to evaluate the performance of LES method for simulation of t

Integrated Assessment Modeling of Air Pollution in Four European Countries.

The integrated assessment modeling on acid rain has incorporated several related effects and pollutants into a multi-pollutant/multi-effect approach, resulting in complex integrated models and policy assessments. The development and implementation of effects-oriented cost-effective emission reduction strategies in Europe are based on integrated assessment models. The project on national integrated

Phenolic Acid Nanoparticle Formation in Iron-Containing Aqueous Solutions.

This paper presents results which show that the interaction between two phenolic acids, p-coumaric and caffeic acid, with iron results in the formation of meta-stable colloidal nano particles. The particles are characterized with dynamic light scattering and cryo-transmission electron microscopy. The results show that the nanoparticle formation is an important feature of phenolic acids which is li