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Biogeografisk uppföljning 2019 av dagfjärilar inom habitatdirektivet

Rapporten sammanfattar fjärilsinventeringar utförda 2019 inom Biogeografisk uppföljning som drivs av Naturvårdsverket. I fjällområdet kunde totalt 36 ytor inventeras och sammanlagt noterades 84 högnordiska blåvingar på 17 av de inventerade ytorna och 11 dvärg¬pärlemorfjärilar på 5 ytor. Inga fynd av fjällsilversmygare gjordes på någon av de 3 ytor som inventerades. Svartfläckig blåvinge observerad

Läsförståelse i alla ämnen (generell text)

Alla elever behöver få möjlighet att öva upp sin läskompetens för att vara rustade för att möta det stora antal texter som de kommer att stöta på under skoltiden och i livet utanför skolan. Med hjälp av lässtrategier och med stöd av de samlade språkliga resurserna som finns att tillgå kan en ämneslärare hjälpa nyanlända elever att öva upp denna kompetens.

Measurable residual disease and clonal evolution in acute myeloid leukemia with focus on NPM1-mutations

Acute myeloid leukemia (AML) is the most common form of acute leukemia in adults, with mutations in the NPM1 gene occurring in almost one third of all cases. The ability to detect residual leukemia below the resolution of conventional microscopy is crucial for evaluation of relapse risk after therapy. In principle, this can be achieved by measuring residual disease (MRD) with two different approac

Executive functioning in psychiatric patients with deliberate self-harm, as compared with a psychiatric and a healthy comparison group

Introduction: Deliberate self-harm (DSH) is a common symptom in psychiatric disorders. It is a cross-diagnostic symptom, although it has mainly been associated with borderline personality disorder (BPD). Research has suggested an association between DSH and deficits in executive functioning. The main aim of the current study was to assess three specific aspects of executive functioning (EF) (worki

Efficacy of an implementation package on documentation of central venous catheter insertions : an observational study

BACKGROUND: Proper documentation of central venous catheter (CVC) insertions in electronic healthcare records is the basis for good follow-up and quality assurance. We have noted serious deficiencies in the documentation of CVC insertions and introduced an implementation package with the purpose of increasing the completeness of this documentation. The aim of the present study was to estimate the

Predictive Force-Centric Emergency Collision Avoidance

A controller for critical vehicle maneuvering is proposed that avoids obstacles and keeps the vehicle on the road while achieving heavy braking. It operates at the limit of friction and is structured in two main steps: a motion-planning step based on receding-horizon planning to obtain acceleration-vector references, and a low-level controller for following these acceleration references and transf

Exploring the miRNA profile of medium spiny neurons using retrograde transport in rats

The basal ganglia play an essential role in movement selection and control. It is therefore not surprising that they are central to neurodegenerative diseases like Parkinson’s disease and Huntington’s disease. As such, greater knowledge of how the different parts of the basal ganglia behave, both in their normal and in disease states, will increase our understanding of the system and help in findi

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The political development in Belarus differs significantly from that of its western neighbors. An authoritarian, populist regime was established in 1994 on a platform of anti-corruption, Soviet nostalgia, and a rhetorical commitment to the reunification of the east Slavic lands into one state. Over his long rule, Aliaksandr Lukashenka has showed considerable aptitude in adjusting to a changing geo

Feedback from HTC Vive Sensors Results in Transient Performance Enhancements on a Juggling Task in Virtual Reality

Virtual reality headsets, such as the HTC Vive, can be used to model objects, forces, and interactions between objects with high perceived realism and accuracy. Moreover, they can accurately track movements of the head and the hands. This combination makes it possible to provide subjects with precise quantitative feedback on their performance while they are learning a motor task. Juggling is a cha

IL-15 Upregulates Telomerase Expression and Potently Increases Proliferative Capacity of NK, NKT-Like, and CD8 T Cells

Interleukin-15 (IL-15) is a cytokine that has been shown to expand CD8 T cell and natural killer (NK) cell populations, and therefore has potential for potentiating adoptive immune cell therapy for cancer. Previously, IL-15 has been shown to induce proliferation of CD8 memory T cells through activation of telomerase. Here, we investigated whether telomerase is also activated during the IL-15 media

Prostate cancer cells enhance interleukin-15-mediated expansion of NK cells

ObjectivesTo identify cytokines that can activate and expand NK cells in the presence of prostate cancer cells in order to determine whether these agents may be useful in future intra‐tumoural administration in pre‐clinical and clinical prostate cancer trials.Materials and MethodsLymphocytes isolated from normal donor blood were set up in co‐cultures with either cancer or non‐cancerous prostate ce

SOXC transcription factors in mantle cell lymphoma : the role of promoter methylation in SOX11 expression

The related transcription factors SOX11, SOX4 and SOX12 (classified as the SOXC family) compete for the same target genes. SOX11 is expressed in most mantle cell lymphomas (MCL) but a small subset is, like normal lymphocytes, SOX11 negative. Here we report the variable expression of SOX4 and high expression of SOX12 in MCL compared to non-malignant tissue. Our results show that the expression of t

The subcellular Sox11 distribution pattern identifies subsets of mantle cell lymphoma : correlation to overall survival

Gene expression analysis demonstrated high expression of the neuronal transcription factor SOX11 in mantle cell lymphoma (MCL). In contrast to follicular lymphoma, small lymphocytic lymphoma and reactive lymphoid tissue, most MCLs tested (48/53 patients) expressed sox11 protein in the nucleus. Therefore nuclear sox11 expression represents a new tumour marker for a subset of MCL. However, 5/53 MCL

Influence of rimonabant treatment on peripheral blood mononuclear cells; flow cytometry analysis and gene expression profiling

The cannabinoid receptor type 1 (CB1) antagonist rimonabant has been used as treatment for obesity. In addition, anti-proliferative effects on mitogen-activated leukocytes have been demonstrated in vitro. We have previously shown that rimonabant (SR141716A) induces cell death in ex vivo isolated malignant lymphomas with high expression of CB1 receptors. Since CB1 targeting may be part of a future