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Protein assemblies are some of the most complex molecular machines in nature. They facilitate many cellular functions, from DNA replication to molecular motion, energy production, and even the production of other proteins. In a series of 3 papers, we analyzed the structure, developed structure prediction tools, and design tools, for different protein assemblies. Many of the studies were centered a
Legal tech is growing, and its growth provokes anxieties about the future of the legal profession as such. In this article, we examine the impact of legal tech on the central role of lawyers at law firms in crafting an imagined ‘right legal answer’ by drawing on Duncan Kennedy’s suggestion that a claim to the rightness of one’s legal propositions is a central characteristic of the legal profession
While it is widely acknowledged that entrepreneurial processes are embedded in an institutional framework, understanding exactly how institutions impact Entrepreneurial Ecosystems (EEs) remains a challenge. This is especially the case for informal institutions, and in particular those not directly related to entrepreneurship support. This paper contributes to this gap by addressing the question: H
During the recent years, the question of whether an Entrepreneurial Ecosystem emerges organically or is man-made has been disputed. This paper explores the case of an Entrepreneurial Ecosystem in a developing country. We argue that in the context of lagging industrial development and weak institutions, a lead actor needs to step in to aid the emergence of an Entrepreneurial Ecosystem. We argue tha
Technological innovation is still a challenge for SMEs in emerging countries, mainly due to the lack of financial, structural, capital, and proper managerial resources. Covid-19 presented a scenario that increased difficulties for companies, especially of this kind, and at the same time presented a necessity-driven impulse to look for innovative solutions. This study aimed to analyze the drivers o
Nowadays, numerous specialized systems, ranging from electronics to energy production processes can be found both in science and industry. However due to their specialized nature they often exhibit high sensitivity to intrusive measurements, which can potentially perturb the sought-after characteristics or quantity and consequently compromise overall accuracy. In these scenarios, optical measureme
Comparing source and target media products is the main intermedial method for studying adaptations. The inventory of similarities and differences produced by such an endeavour provides evidence for the processes of transfer and transformation that have happened between the two media. But the finished media products are not the only traces of the process of adaptation. In practices of adaptation th
Time-resolved x-ray solution scattering (TR-XSS) is a sub-field of structural biology, which observes secondary structural changes in proteins as they evolve along their functional pathways. While the number of distinct conformational states and their rise and decay can be extracted directly from TR-XSS experimental data recorded from light-sensitive systems, structural modeling is more challengin
Background: New CKD-EPI and EKFC estimated GFR (eGFR) equations usingcreatinine (eGFRcr), cystatin C (eGFRcys) and both (eGFRcr-cys) have sufficientaccuracy for use in clinical practice. A better understanding of the equations, includingtheir performance in race, sex and age subgroups, is important for selection of eGFRequations for global implementation.Methods: We evaluated performance (bias and
The change in constituent order in English is one of the most thoroughly investigated changes in the history of the English language. Even so, there is still disagreement among scholars as to what caused the change. The aim of this article is to argue that it was the influence of the Scandinavians and their language, Old Norse, that caused English to abandon the SOV constituent order and instead a
At first glance, the syntax of ancient Old English appears reminiscent of the syntax of the Present-Day German language. A number of shared syntactic traits such as Subject Object Verb constituent order, Verb Second, and a complicated inflectional system have caused the two languages to be compared by scholars, who often have referred to German as simply a present-day version of the now far-gone O
Although much research has been done on case and sequence within coordination structures separately, few studies have investigated the impact the two have on each other. Moreover, very little research has dealt with the striking similarity of English and Danish regarding case and sequence within CoDPs. This thesis, therefore, aimed to explore this matter to uncover the complex system which determi
This open access book shows how geographical scales are made through music.Scales are sets of spatial frames, abstractions or categories that denote the size, proportion, level, extent or hierarchical relations of phenomena. They are neither natural nor neutral but actively produced, with real political effects. But what role do cultural practices play in the production of scale?Phil Dodds address
Future exemplary education should foster inclusive and respectful learning environments to meet new challenges like digital inequality and power concentration. In the new normal of education due to COVID-19, inclusive online disaster risk reduction (DRR) education is essential. Therefore, this article aims to investigate the current status quo of inclusive online and distance DRR education and its
The International Monetary Fund (IMF) provides financial assistance to its member countries in economic difficulties but at the same time requires these countries to reform public policies. In several contexts, these reforms have been at odds with population health and material living standards. While researchers have empirically analyzed the consequences of IMF reforms on health, no analysis has
This paper shows that versions of prioritarianism that focus at least partially on well-being levels at certain times conflict with conventional views of prudential value and prudential rationality. So-called timeslice prioritarianism, and pluralist views that ascribe importance to timeslices, hold that a benefit matters more, the worse off the beneficiary is at the time of receiving it. We show t
Nationalism has trumped solidarity, resulting in unnecessary loss of life and inequitable access to vaccines and therapeutics. Existing intellectual property (IP) regimens, trade secrets and data rights, under which pharmaceutical firms operate, have also posed obstacles to increasing manufacturing capacity, and ensuring adequate supply, affordable pricing, and equitable access to COVID-19 vaccine
