Objective and Background: Pulse wave amplitude (PWA) derived from the digital vascular bed has been used in sleep studies. The nocturnal attenuation of PWA has been shown to reflect sympathetic activation during sleep. We assessed the relationship between nocturnal PWA attenuation and office blood pressure (BP). Methods: Eighty-one subjects (46 men; age 60 7 years: body mass index [BMI] 28.2 +/- 4

BACKGROUND: Positron emission tomography (PET) provides metabolic information of tissues in vivo. The purpose of this study was to assess the value of PET with 2-[(18) F] fluoro-2-deoxy-D-glucose (FDG) in prediction of therapy outcome (tumor response, survival, and locoregional control) in locally advanced HNSCC. METHODS: Between 1993 and 1999 47 patients underwent PET before (PET(1)) and after (P

In experiments, the feasibility was demonstrated of generating multi-MeV electrons in a form of a collimated beam utilizing a table-top laser system delivering 200 fs pulses with P-L=1.2 TW and 10 Hz capability. The method uses the process of relativistic self-channeling in a high-density gas jet producing electron densities in the range of 3x10(19)-6x10(20) cm(-3). In a thorough investigation, an

Objective: The objective was to analyse relationships between inspiratory and expiratory static and dynamic elastic pressure-volume (P-el/V) curves in healthy pigs. Design: The modulated low flow method was developed to allow studies also of the expiratory P-el/V curves. Static P-el/V (P-el,P-st/V) and dynamic P-el/V (P-el,P-dyn/V) loops were studied in healthy pigs. Setting: Animal research labor

The triallylphosphine-substituted clusters [Ru3(CO)11{P(CH2CH=CH2)3}], [Ru3(CO)10{P(CH2CH=CH2)3}2] and [Ru3(CO)10{;-CH2=CHCH2P(CH2CH=CH2)2}] have been prepared; reaction of [Ru3(CO)10{;-CH2=CHCH2P(CH2CH=CH2)2}] with phosphines/phosphites leads to cleavage of the Ru–allyl -bond and formation of [Ru3(CO)11{P(CH2CH=CH2)3}(PR3)].

An increasing number of studies describe moving hybrid zones. This raises the issue of their actual frequency and emphasizes the need for methods that enable the detection of zone movements without historical records. Asymmetric introgression, usually considered as a signature of geographical shift, might be misleading when applied to mitochondrial or potentially non-neutral markers. We investigat

The microarray technique requires the organization and analysis of vast amounts of data. These data include information about the samples hybridized, the hybridization images and their extracted data matrices, and information about the physical array, the features and reporter molecules. We present a web-based customizable bioinformatics solution called BioArray Software Environment (BASE) for the

The memory T-cell population is a heterogeneous population, including both effector cells, which exert a direct secondary immune response, and resting or intermediate cells, which serve as a reservoir and exert a possible regulatory role. To further dissect the T-cell memory population residing in the CD4(+) CD45RO(+) T-cell pool, we studied the functional properties of memory populations identifi

Following the identification of metabolite signals in the in vivo MR spectrum, quantification is the procedure to estimate numerical values of their concentrations. The two essential steps are discussed in detail: analysis by fitting a model of prior knowledge, that is, the decomposition of the spectrum into the signals of singular metabolites; then, normalization of these signals to yield concent

The distribution of low-arctic megafaunal remains in time and space from the area previously covered by the Scandinavian Ice Sheet(SIS) suggests the presence of breeding mammoth populations in the circum-Baltic region during the time interval from 44 to 26 ka ago. The transport history of 30 mammoth teeth and bones from southern and north-central Sweden was estimated and the remains were subjected

A dinuclear manganese complex ([Mn2L(m-OAc)2]PF6) has been synthesized, where L is the trianion of 2,6-bis{[(2-hydroxy-3,5-di-tert-butylbenzyl)(2-pyridylmethyl)amino]methyl}-4-methylphenol, a ligand with three phenolate groups. The two pseudo-octahedrally coordinated Mn ions are bridged via the two bidentate acetate ligands and the 4-methylphenolate group of the ligand. We have characterized the c

BACKGROUND Autoinflammatory diseases manifest inflammation without evidence of infection, high-titer autoantibodies, or autoreactive T cells. We report a disorder caused by mutations of IL1RN, which encodes the interleukin-1-receptor antagonist, with prominent involvement of skin and bone. METHODS We studied nine children from six families who had neonatal onset of sterile multifocal osteomyelitis

This paper addresses the inverse problem of reconstructing a medium’s instantaneous, nonlinear response to electromagnetic excitation. Using reflection and transmission data for an almost arbitrary incident field on a homogeneous slab, we are able to obtain the nonlinear constitutive relations for both electric and magnetic fields, with virtually no assumptions made on the specific form of the rel

Species of Haemoproteus (Haemosporida: Haemoproteidae), avian haemosporidians, have traditionally been described based on morphology of their gametocytes and on limited experimental information on their vertebrate host specificity. We investigated to what extent the morphological species are represented by monophyletic groups based on DNA sequence data using 2 different fragment lengths of the cyt

Resonant core spectroscopies are applied to a study of the excited electron transfer dynamics on a low-femtosecond time scale in systems of aromatic molecules (isonicotinic acid and bi-isonicotinic acid) adsorbed on a rutile TiO2(110) semiconductor surface. Depending on which adsorbate state is excited, the electron is either localized on the adsorbate in an excitonic effect, or delocalizes rapidl

The Euro50 is a proposed optical telescope with an equivalent aperture of 50 m. It will have a segmented primary mirror and full adaptive optics. To study the interaction of the telescope structure, the control system and the optics, an integrated simulation model has been formulated. The mechanical model is a modal version of an Ansys finite element model. The optics model is based on ray tracing

LOV (light-oxygen-voltoge-sensitive) domains comprise the lightsensitive parts of many blue light photoreceptor proteins. Photoexcitation of the chromophore flavin mononucleotide (FMN) in these LOV domains leads to formation of a covalent adduct between FMN and a cysteine residue. So for, the electronically excited singlet and triplet states of FMN have been identified as the only intermediates in