INTRODUCTION: A diet containing a high amount of fat has been shown, in short-term studies, to increase the expression of pancreatic lipase and colipase. AIM: To investigate the effects of long-term high-fat-feeding (113 days) on the mRNA expression of pancreatic lipase, colipase, pancreatic lipase-related proteins (1 and 2), and uncoupling proteins during the development of obesity and glucose in

Aim: The objective of the present study was to evaluate the prospective use of immunohistochemistry (IHC) for histopathological diagnosis of sentinel lymph node(s) (SLN) in primary breast cancer using stage migration and non-SLN metastases as endpoints in relation to metastatic involvement. Method: Serial sectioning and prospective use of IHC were applied to SLN examination in addition to routine

halidomide is an immunomodulating agent shown to prolong graft survival in experimental skin, renal, cardiac and bone marrow transplantation. The main purpose of the present study was to investigate the possible additive effect of combining thalidomide with cyclosporin A (CyA). Members of our group have previously created a bsis for such studies by demonstrating the ability of Linomide to abolish

Twenty-eight cases of hepatitis C virus (HCV) infection were identified in children in a pediatric oncology ward during 2 nosocomial outbreaks. HCV infection spontaneously cleared in 6 patients (21%). Eleven patients with persistent HCV viremia who had malignant diseases in remission after treatment were given a 48-week course of combined therapy with interferon-alpha (5x106 U 3 times weekly) and

Background. The role of Helicobacter pylori infection in the development of oesophageal malignancies was investigated through a multivariate conditional logistic regression analysis in a nested case-control study. Methods. Blood samples and a questionnaire on smoking and alcohol habits were collected from a cohort of 32,906 city residents during a health-screening programme between 1974 and 1992.

Uptake of P(P-32) and Ca(Ca-45) by seedlings of Picea abies (L.) Karst and Betula pendula Roth, non-mycorrhizal or mycorrhizal with Paxillus involutus (Batsch: Fr) Fr. was studied. Seedlings were grown in unamended peat (pH 4.0) or in peat limed (CaO) to pH 5.1 or 6.1. A double-labelled (P-32 and Ca-45) complete nutrient solution was added to the peat 7 wk after planting. An 8 d period was allowed

Ion-ion correlations play an important role in liquid dispersion with, strong eleetrostatic inlet-actions. Examples can be found in very diverse areas with the setting of cement paste as one extreme and the compactation, of DNA as another. One particularly spectacular effect of ion-ion correlations is that the traditional double layer repulsion sometimes can be converted into a net attraction. Thi

In this work, the adsorption of citric (2-hydroxypropane-1,2,3-tricarboxylic acid) and tricarballylic (propane-1,2,3-tricarboxylic acid) acids onto alpha-FeOOH (goethite) in aqueous suspensions was studied as a function of pH and total ligand concentration in 0.1 M NaCl at 25.0 degrees C, and the molecular structures of the surface complexes formed were analyzed by means of ATR-FTIR spectroscopy.

The luminescence polarization properties of GaInP islands have been investigated. The islands, which form during overgrowth of InP quantum dots, were studied using scanning tunneling luminescence (STL) and photoluminescence (PL). STL from these islands shows emission at an energy below the main emission peak of the bulk GaInP. The linear PL polarization anisotropy was measured at low temperature,

Quasistatic propagation of a short edge crack, located within one grain of a bcc material has been studied using a discrete dislocation technique. The geometry is modelled by distributed dislocation dipole elements and the plasticity by discrete dislocations. The crack is assumed to grow through a single shear mechanism due to nucleation and annihilation of dislocations along preferred slip planes

School-aged children often experience acute respiratory symptoms. In a multicentre European study, the association between chronic respiratory symptoms (reported in a questionnaire), skin-prick test results, and lung function, and the occurrence of acute respiratory morbidity, was examined among children aged 6-12 yrs with chronic respiratory symptoms. Children with chronic respiratory symptoms, l

Microfungal species composition was studied in coniferous forest soils which had been treated with lime or wood ash. The pH increased by about 2.5 units at the highest rate of application. Fungi were isolated 4–5 years after the treatments using a soil washing technique. At one site, Öringe, clear differences in species composition due to liming were found. Penicillium spinulosum, Oidiodendron cf.

An initial-boundary value problem to a system of nonlinear partial differential equations, which consists of a hyperbolic and a parabolic part, is taken into consideration, The problem is discretised by a compact finite difference method. An approximation of the numerical solution is constructed, at which the difference scheme is linearised. Nonlinear convergence is proved using the stability of t

We consider Bose-Einstein-condensed atoms confined in a toroidal trap. Under conditions of one-dimensional behavior, the density distribution of the atoms may be exponentially localized or delocalized, even for very small variations in the trapping potential along the torus. For similar reasons, small irregularities of the trap may also have a very pronounced effect on the density of the cloud. Th

Upon sustained insult, kinins are released and many kinin responses, such as inflammatory pain, adapt from a B2 receptor (B2R) type in the acute phase to a B1 receptor (B1R) type in the chronic phase. In this study, we show that kinins modulate receptor endocytosis to rapidly decrease B2R and increase B1R on the cell surface. B2Rs, which require agonist for activity, are stable plasma membrane com

Several matrix metalloproteinases and serine proteinases are upregulated in migrating keratinocytes during cutaneous wound repair. Single cell culture studies indicate the necessity for matrix metalloproteinases but not for serine proteinases in keratinocyte locomotion. To account for epithelial-mesenchymal interactions, an ex vivo human skin wound model was used to investigate the contribution of

"I have dealt with many different transformations with various periods of time, but the quickest that I have met was my own transformation in one moment from a physicist to a chemist." Ernest Rutherford (Nobel Banquet, 1908) This article is about how Ernest Rutherford (1871-1937) got the 1908 Nobel Prize in Chemistry and why he did not get a second Prize for his subsequent outstanding discoveries

Macroporous polyacrylamide gels (MPAAGs) with unique elastic morphology and open porous structure are prepared at subzero temperatures. The porous structure of MPAAGs consisting of large, 1 - 100 mu m-sized interconnected pores, is controlled by the freezing temperature, the content of the initiator system ( ammonium persulfate and N,N,N',N'-tetramethyl-ethylenediamine) in the initial reaction mix