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Thermoreversible gels of hydrophobically modified hydroxyethyl cellulose cross-linked by amylose

Aqueous mixtures of hydrophobically modified hydroxyethyl cellulose (HMHEC) or unmodified hydroxyethyl cellulose (HEC), with amylose (AM) or potato amylopectin (PAP), have been investigated by rheology, turbidity, and H-1 NMR measurements. It is concluded that the AM molecules cross-link HMHEC chains by forming helical inclusion complexes with the hydrophobic side chains of HMHEC, leading to therm

Comparison of the fermentability of enzymatic hydrolyzates of sugarcane bagasse pretreated by steam explosion using different impregnating agents

Sugarcane bagasse is a potential lignocellulosic feedstock for ethanol production, since it is cheap, readily available, and has a high carbohydrate content. In this work, bagasse was subjected to steam explosion pretreatment with different impregnation conditions. Three parallel pretreatments were carried out, one without any impregnation, a second with sulfur dioxide, and a third with sulfuric a

Attenuation correction in quantitative SPECT of cerebral blood flow: a Monte Carlo study

Monte Carlo simulation has been used to produce projections from a voxel-based brain phantom, simulating a 99mTc-HMPAO single photon emission computed tomography (SPECT) brain investigation. For comparison, projections free from the effects of attenuation and scattering were also simulated, giving ideal transaxial images after reconstruction. Three methods of attenuation correction were studied: (

Long-term progression-free survival of mantle cell lymphoma after intensive front-line immunochemotherapy with in vivo-purged stem cell rescue: a nonrandomized phase 2 multicenter study by the Nordic Lymphoma Group

Mantle cell lymphoma (MCL) is considered incurable. Intensive immunochemotherapy with stem cell support has not been tested in large, prospective series. In the 2nd Nordic MCL trial, we treated 160 consecutive, untreated patients younger than 66 years in a phase 2 protocol with dose-intensified induction immunochemotherapy with rituximab (R) + cyclophosphamide, vincristine, doxorubicin, prednisone

Social defeat: risk factor for schizophrenia?

The hypothesis that chronic and long-term experience of 'social defeat' may increase the risk for schizophrenia is proposed. This increased risk may result from sensitisation of the mesolimbic dopamine system and/or increased baseline activity of this system. Data supporting the social defeat hypothesis are presented.

Antenna diversity evaluation for mobile terminals

In this paper we are focusing on the practical, engineering way of evaluating and characterizing the multi-channel antenna solutions on the mobile terminal. Two methods of calculating the parameters, describing the diversity performance, are described and the practical use of the methods in simulations and measurements are presented and evaluated. The time saving aspect of using the scattering par

Path generation issues for survivable network design

Link dimensioning and routing problems in resilient network design are considered. Reliable network operation is ensured by means of flow restoration which is performed on preselected protection (backup) paths that can absorb traffic overflows from failed primary paths. Backup and primary flows use separated link capacities, and can be split among many paths. In the paper, two restoration models a

Neuroendocrine cells and nerves in the prostate of the guinea pig: effects of peripheral denervation and castration

BACKGROUND: Neuroendocrine (NE) cells and nerves in the prostate gland are thought to play a central role in the regulation of growth, cellular differentiation and homeostasis of secretory activity. The objective of this experimental study was to describe the effects of peripheral denervation and castration on NE cells and nerves in the guinea pig prostate. METHODS: Guinea pigs underwent sham-oper

Characterization of chemical substitution of hydroxypropyl cellulose using enzymatic degradation

The distribution of substituents along the polymer backbone will have a strong influence on the properties of modified cellulose. Endoglucanases were used to degrade a series of hydroxypropyl cellulose (HPC) derivatives with a high degree of substitution. The HPCs were characterized with cloud-point analysis prior to degradation. The extent of enzymatic degradation was determined with size-exclusi

Prognostic factors in invasive cutaneous malignant melanoma: a population-based study and review

A population-based study from Sweden identified 711 patients with cutaneous malignant melanoma diagnosed in 1965, 1975, 1985 and 1989. Prognostic factors were evaluated and a review of the literature was performed. On univariate analysis, thick tumours (> 0.8 mm) (odds ratio [OR] 1.8, 95% confidence interval [CI] 1.6-2.1), increasing Clark level (OR 1.8, 95% CI 1.6-2.0), ulceration (OR 1.8, 95% CI

Examination of aerosol effects on precipitation in deep convective clouds during the 1997 ARM summer experiment

It has been generally accepted that increasing aerosols suppress precipitation. The aerosol-induced precipitation suppression was suggested by the study of shallow stratiform clouds. Recent studies of convective clouds showed increasing aerosols could increase precipitation. Those studies showed that intense feedbacks between aerosols and cloud dynamics led to increased precipitation in some cases

Pharmacokinetics, pharmacodynamics and clinical effects of the oral direct thrombin inhibitor ximelagatran in acute treatment of patients with pulmonary embolism and deep vein thrombosis

Introduction: Ximelagatran is a novel, oral direct thrombin inhibitor that is currently being investigated for the prophylaxis and treatment of thromboembolic events. This study evaluated the pharmacokinetics, pharmacodynamics, and clinical effects of melagatran, the active form of ximelagatran, in patients with both deep vein thrombosis (DVT) and pulmonary embolism (PE). Materials and methods: In

Crystal structure of ferrochelatase: the terminal enzyme in heme biosynthesis

BACKGROUND: The metallation of closed ring tetrapyrroles resulting in the formation of hemes, chlorophylls and vitamin B12 is catalyzed by specific enzymes called chelatases. Ferrochelatase catalyzes the terminal step in heme biosynthesis by inserting ferrous ion into protoporphyrin IX by a mechanism that is poorly understood. Mutations in the human gene for ferrochelatase can result in the diseas

Screening for Infants With Developmental Deficits and/or Autism A Swedish Pilot Study.

The purpose of this study was to develop an instrument (SEEK) for the early detection of developmental deficits and/or autistic spectrum disorders among children by the age of 8 months at eight child health care centers in southern Sweden. Health visitors, trained by the research team, screened 312 infants. SEEK captured 5 infants with several points. Twenty-one percent of the infants obtained at

Polymorphisms in the IL-10 but not in the IL-1{beta} and IL-4 genes are associated with inhibitor development in patients with hemophilia A.

The aim of the Malmö International Brother Study (MIBS) is to evaluate host genetic factors associated with the development of inhibitory antibodies in patients with hemophilia. Factor VIII gene mutations and genetic polymorphisms of the IL1beta, IL4, and 100 genes, known to influence antibody production in autoimmune diseases, were analyzed in 164 patients (124 with severe, 26 with moderate, and