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Maternal human polyomavirus infection and risk of neuroblastoma in the child.

To investigate if polyomavirus infection during pregnancy is linked to development of neuroblastoma in the child, serum samples of 115 index mothers from the pregnancy where the child eventually developed neuroblastoma were identified and matched with serum samples from 8 control mothers per index mother. The samples were tested for. specific IgG and IgM antibodies to BK and JC virus using enzyme

Spin-orbit selectivity observed for the HCl+ ((X)over-tilde (II)-I-2) state using resonant photoemission

We report the experimental observation of a strongly selective population of the spin-orbit components in the HCl+ (X) over tilde (2)Pi(Omega) states after excitation into the dissociative 2p(-1)6sigma* core excited state. A progression of highly excited vibrational states with either the Omega=3/2 or Omega=1/2 component of the final state is populated, respectively, when the excitation is tuned i

Patterns of allozyme variation in Nordic Pilosella

Patterns of allozyme variation have been investigated in 101 clones representing most of the morphological variation (and taxa) found in the amphi-apomictic genus Pilosella Hill. in the Nordic countries. Levels of variation were very high, both within narrowly defined taxa and within the whole data-set, but the correlation between a morphology-based taxonomy and patterns of allozyme variation was

Work Disability in Rheumatoid Arthritis -- Development over 15 Years and Evaluation of Predictive Factors Over Time.

Objective. To investigate work disability rates over 15 years in an early rheumatoid arthritis (RA) cohort and to evaluate predictive factors during the course of the study. Methods. All patients with early RA of working age (n = 148) were followed and treated at a team care unit. Mean disease duration at inclusion was 1 year. Work characteristics and disease-related variables were recorded annual

The Strike of the Demon: On Fitting Pro-attitudes

According to an influential tradition in value analysis, to be valuable is to be a fitting object of a pro-attitude. If it is fitting to favor an object for its own sake, then, on this view, the object has final value, that is, it is valuable for its own sake. If it is fitting to have a pro-attitude toward an object for the sake of its effects, then its value is instrumental. And so on. Disvalue i

Designing simultaneous saccharification and fermentation for improved xylose conversion by a recombinant strain of Saccharomyces cerevisiae.

Wheat straw is an abundant agricultural residue which can be used as a raw material for bioethanol production. Due to the high xylan content in wheat straw, fermentation of both xylose and glucose is crucial to meet desired overall yields of ethanol. In the present work a recombinant xylose fermenting strain of Saccharomyces cerevisiae, TMB3400, cultivated aerobically on wheat straw hydrolysate, w

Interleukin-1-receptor antagonist in type 2 diabetes mellitus

Background: The expression of interleukin-1-receptor antagonist is reduced in pancreatic islets of patients with type 2 diabetes mellitus, and high glucose concentrations induce the production of interleukin-1(beta) in human pancreatic beta cells, leading to impaired insulin secretion, decreased cell proliferation, and apoptosis. Methods: In this double-blind, parallel-group trial involving 70 pat

Effects of buffering in hypercapnia and hypercapnic hypoxemia

Anesthetized, paralyzed and mechanically ventilated pigs were exposed to extreme hypercapnia (PaCO2 approximately 20 kPa) at FiO2 0.4 for 480 min, with (n = 6) or without (n = 6) continuous infusion of isotonic buffers (bicarbonate and trometamol). Arterial pH was higher in buffered animals than controls, 7.21 +/- 0.01 vs 7.01 +/- 0.01 (mean +/- s.e.mean, P < 0.01). Serum osmolality and PaCO2 did

Influence of an enriched environment and cortical grafting on functional outcome in brain infarcts of adult rats

The purpose of this work was to study if enriched housing conditions and fetal neocortical transplantation could enhance the functional outcome after focal brain ischemia in adult rats. The right middle cerebral artery (MCA) was ligated in 34 inbred, spontaneously hypertensive male rats, which were then randomly divided into three groups. Groups A and B were transferred to an enriched environment,

Determiner use in Italian Swedish and Italian German children: Do Swedish and German represent the same parameter setting?

In this article we compare the acquisition of determiners in bilingual children acquiring Italian simultaneously with German or Swedish. We are concerned with cross-linguistic differences in the rate of acquisition and we discuss in particular the Nominal Mapping Parameter, a model according to which the syntax-semantics interface is crucial in acquisition and which predicts similar developmental

Patch testing with a new fragrance mix - reactivity to the individual constituents and chemical detection in relevant cosmetic products

A new fragrance mix (FM II), with 6 frequently used chemicals not present in the currently used fragrance mix (FM I), was evaluated in 6 dermatological centres in Europe, as previously reported. In this publication, test results with the individual constituents and after repeated open application test (ROAT) of FM II are described. Furthermore, cosmetic products which had caused a contact dermatit

Revision of the Botanophila helviana species group (Diptera: Anthomyiidae) in Europe

Species of the Botanophila helviana species group are small, blackish anthomyiids known from temperate to subarctic (northern/elevated) parts of the Holarctic Region. Adult flies are anthophilous, obtaining pollen and nectar from various flowering plants. Preliminary evidence suggests that the larvae may attack developing seed heads of Ranunculus (Ranunculaceae). The male and female terminalia are

The geochemistry of the Sorvik granite - a TIB-1 granite

The Sorvik granite occurs as rounded massifs in the Revsund granite in central Sweden. The rock is medium-grained with rounded quartz crystals ('drop quartz') and occasional, sometimes albiterimmed megacrysts of K-feldspar. It is a faintly peraluminous 1-type granite with some A-type affinities showing a limited chemical variation. The SiO2 content normally varies between 68 and 77 weight%. The ro

Reductive openings of acetals: Explanation of regioselectivity in borane reductions by mechanistic studies

The mechanisms of regioselective reductive openings of acetals were investigated in several model systems by a combination of Hammett plots, kinetic experiments, density functional calculations, and B-11 NMR. The regioselectivity of borane reductions of cyclic acetals can be controlled by the choice of borane. Lewis acid activation of BH3 center dot NMe3 increases the reaction rate and renders the