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The onset of deglaciation of Cumberland Bay and Stromness Bay, South Georgia

Carbon dating of basal peat deposits in Cumberland Bay and Stromness Bay and sediments from a lake in Stromness Bay, South Georgia indicates deglaciation at the very beginning of the Holocene before c. 9500 C-14 yr BP. This post-dates the deglaciation of one local lake which has been ice-free since at least 15 700 C-14 yr BP on account of its atypical geomorphological location. The latter indicate

Congenital and acquired activated protein C resistance.

Resistance to the anticoagulant action of activated protein C, APC resistance, is a highly prevalent risk factor for venous thrombosis among individuals of Caucasian origin. In most cases, APC resistance is associated with a single missense mutation in the gene for coagulation factor V (FVLeiden), which predicts the replacement of Arg506 with a Gln at one of the cleavage sites for APC in factor V.

Analyzing tumor gene expression profiles

A brief introduction to high throughput technologies for measuring and analyzing gene expression is given. Various supervised and unsupervised data mining methods for analyzing the produced high-dimensional data are discussed. The main emphasis is on supervised machine learning methods for classification and prediction of tumor gene expression profiles. Furthermore, methods to rank the genes accor

The Environmental Implications of Electronic Commerce - A Critical Review and Framework for Future Investigation

There are accelerating trends for the implementation of electronic commerce(e-commerce) as an extra marketing channel for selling products globally via the access of the Internet. This is expected to in¯uence the shape of future cities and the conservation of natural resources. This paper critically reviews the current research work to date regarding the environmental implications of e-commerce. T

The influence of dietary fibre source and gender on the postprandial glucose and lipid response in healthy subjects.

BACKGROUND: Consumption of soluble dietary fibre is correlated with decreased postprandial glucose and insulin responses and hence has beneficial effects on the metabolic syndrome. AIM OF THE STUDY: To investigate the effects on postprandial glucose, insulin and triglyceride concentrations of meals enriched with soluble dietary fibres from oats, rye bran, sugar beet fibre or a mixture of these thr

Review of current knowledge on HPV vaccination: An Appendix to the European Guidelines for Quality Assurance in Cervical Cancer Screening.

The recognition of a strong etiological relationship between infection with high-risk human papillomavirusses and cervical cancer has prompted research to develop and evaluate prophylactic and therapeutic vaccines. One prophylactic quadrivalent vaccine using L1 virus-like particles (VLP) of HPV 6, 11, 16 and 18 is available on the European market since the end of 2006 and it is expected that a sec

Participation in Green Consumer Policies: Deliberative Democracy under the Wrong Conditions?

In policy debates about reducing environmental and social harms, political consumerism is often called for by actors from a broad political spectrum. This paper examines traits of deliberative democracy in cases where instruments of political consumerism (eco-labelling, certificates and standards) are developed. The empirical cases are processes surrounding eco-labelled, standardised forestry, foo

Fruit and vegetable consumption and pancreatic cancer risk in the European Prospective Investigation into Cancer and Nutrition

Many case-control studies have suggested that higher consumption of fruit and vegetables is associated with a lower risk or pancreatic cancer, whereas cohort studies do not support such an association. We examined the associations of the consumption of. fruits and vegetables and their main subgroups with pancreatic cancer risk within the European Prospective Investigation into Cancer and Nutrition

Tourniquet compression: a non-invasive method to enhance nerve regeneration in nerve grafts.

One hindlimb of a rat was subjected to tourniquet compression (150, 200 and 300 mmHg; 2 h). After 6 days a 10 mm sciatic or tibial nerve graft from the compressed limb was sutured to bridge a 3-4 mm gap in the sciatic nerve of the non-compressed limb. The distances of regenerating sensory axons were measured 6 days post surgery (tibial grafts, 8 days). Compression at 200 and 300 mmHg led to signif

Fungus covered insulator materials studied with laser-induced fluorescence and principal component analysis

A method combining laser-induced fluorescence and principal component analysis to detect and discriminate between algal and fungal growth on insulator materials has been studied. Eight fungal cultures and four insulator materials have been analyzed. Multivariate classifications were utilized to characterize the insulator material, and fungal growth could readily be distinguished from a clean surfa

Evolutionary dynamics and population biology of a polymorphic insect

Conspicuous heritable polymorphisms are useful to address the question if morph frequencies are stable or whether they fluctuate between generations. Ecological geneticists have studied colour polymorphisms in the past, but there are few long-term studies of genetic dynamics across multiple generations. We studied morph-frequency dynamics and female fecundity in the trimorphic blue-tailed damselfl

The influence of dominance and diet on individual odours in MHC identical juvenile Arctic charr siblings

No difference in attraction was observed in sibling Artic charr Salvelinus alpinus between water scented by dominant or subordinate major histocompability complex (MHC) identical fish observed in a two-choice fluviarium. In a second experiment, MHC identical sibling donors were given different types of food pellets before the preference test. The test fish showed a significant attraction to the si

Social capital and neo-materialist contextual determinants of sense of insecurity in the neighbourhood: A multilevel analysis in Southern Sweden.

Background: The aim of this study was to investigate the influence of contextual (social capital and neo-materialist) and individual factors on sense of insecurity in the neighbourhood. Methods: The 2000 public health survey in Scania is a cross-sectional study. A total of 13,715 persons answered a postal questionnaire, which is 59% of the random sample. A multilevel logistic regression model, wit

Flexible statistical modelling detects clinical functional magnetic resonance imaging activation in partially compliant subjects.

Clinical functional magnetic resonance imaging (MRI) occasionally fails to detect significant activation, often due to variability in task performance. The present study seeks to test whether a more flexible statistical analysis can better detect activation, by accounting for variance associated with variable compliance to the task over time. Experimental results and simulated data both confirm th

Immobilization of a recombinant Escherichia coli producing a thermostable alpha-L-rhamnosidase: Creation of a bioreactor for hydrolyses of naringin

An U-L-rhamnosidase (E.C. 3.2.1.40) from a newly discovered thermophilic bacterium was expressed in Escherichia coli BL21 DE3 pRIL cells. The cells were immobilized in Ca2+-alginate beads. The temperature of 50 degrees C used in reactions, appeared to be sufficient for making the mesophilic strain porous enough for the substrate to access the cloned thermostable enzyme. Pretreatment of cells with