To investigate the relation between joint involvement in the upper extremities and grip force in patients with early rheumatoid arthritis (RA). An inception cohort of 225 patients with early RA was followed according to a structured protocol. The same rheumatologist assessed all patients for swollen joints and joint tenderness. Grip force was measured (Grippit; AB Detektor, Gothenburg, Sweden) at

The unknown role of the carrier protein transthyretin (TTR) in mechanisms of functional recovery in the postischemic brain prompted us to study its expression following experimental stroke. Male C57/B6 mice (age 9 to 10 weeks) were subjected to permanent focal ischemia induced by photothrombosis (PT) and brain tissues were analyzed for ttr expression and TTR levels at 24 hours, 48 hours, 7 days an

The magnetically frustrated spin ice family of materials is host to numerous exotic phenomena such as magnetic monopole excitations and macroscopic residual entropy extending to low temperature. A finite-temperature ordering transition in the absence of applied fields has not been experimentally observed in the classical spin ice materials Dy2Ti2O7 and Ho2Ti2O7. Such a transition could be induced

We address the interplay of electron-electron (e-e) and electron-phonon (e-ph) interactions in the Hubbard- Holstein model, using a two-component density functional theory. Exchange-correlation potentials constructed via dynamical mean field theory for a D = ∞ Bethe lattice and analytically for an isolated site give a new perspective on e-ph screening of the e-e interactions and its effect on the

Methanol is a genuine candidate on the alternative fuel market for internal combustion engines, especially within the heavy-duty transportation sector. Partially premixed combustion (PPC) engine concept, known for its high efficiency and low emission rates, can be promoted further with methanol fuel due to its unique thermo-physical properties. The low stoichiometric air to fuel ratio allows to ut

Although references to China were few and fragmentary, the example of a ‘stationary’ East Asian Empire featured importantly in Scottish Enlightenment ideas about religion and political economy. David Hume considered whether the apparently long-flourishing system of Chinese government, grounded in rationally deduced deistic ethics, could provide an example for Western nations. Later in the eighteen

Aim: Attention-deficit/hyperactivity disorder (ADHD) is the most common diagnosis within child- and adolescent psychiatry. Waiting lists and delayed care are major issues. The aim was to evaluate if standardized care (SC) for assessment and treatment of uncomplicated ADHD would reduce resource utilization and increase satisfaction with preserved improvement within the first year of treatment. Meth

The complement system plays an important role in varying types of disease, ranging from inflammatory and autoimmune disorders to immune deficiency states. In addition, new settings have emerged where complement analysis is of interest to monitor complement-directed therapy and aid identification of transplant complications. Therefore, it is critical that clinical laboratories offer optimized and t

We present a new algorithm for solving the LPN problem. The algorithm has a similar form as some previous methods, but includes a new key step that makes use of approximations of random words to a nearest codeword in a linear code. It outperforms previous methods for many parameter choices. In particular, we can now solve the (512,18) LPN instance with complexity less than 2 80 operations in expec

Age-related macular degeneration (AMD) is the most common cause of visual impairment in the developed world. A number of patients experience complex lifelike visual experiences—Charles Bonnet syndrome (CBS). In this systematic review, our aim was to provide an overview of the CBS literature in relation to AMD, to determine the prevalence of CBS in patients with AMD and to provide an overview of as

A dominating set of a graph G is a set D⊆ VG such that every vertex in VG- D is adjacent to at least one vertex in D, and the domination number γ(G) of G is the minimum cardinality of a dominating set of G. A set C⊆ VG is a covering set of G if every edge of G has at least one vertex in C. The covering number β(G) of G is the minimum cardinality of a covering set of G. The set of connected graphs

The scientific debate following the initial formulation of the “bad luck” hypothesis in cancer development highlighted how measures based on analysis of variance are inappropriately used for risk communication. The notion of “explained” variance is not only used to quantify randomness, but also to quantify genetic and environmental contribution to disease in heritability coefficients. In this pape

The global anti-doping effort in sport is based upon perceptions of the system as desirable, proper and appropriate and thus considered legitimate. The legitimacy of the anti-doping system has earlier been studied bottom-up, based on the views of athletes. In order to gain greater understanding of legitimation processes, it is also important to study legitimation strategies top-down, used by decis

Objectives: We aimed to investigate the bone mineral density (BMD) in a group of Swedish patients with chronic rhinosinusitis with nasal polyposis (CRSwNP) with or without asthma, as well as to evaluate whether the treatment of this patient group is in accordance with the EPOS recommendations. Design, settings and participants: Adult patients with a diagnosis of CRSwNP, and a history of at least t

Erlotinib (Tarceva) targets the epidermal growth factor receptor (EGFR), which is commonly overexpressed in human cancers, including lung cancer. We show that erlotinib can be labeled with [(11)C] by reacting the normethyl precursor with [(11)C]-methyl iodide. By using the 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide proliferation assay, two lung cancer cell lines (A549 and NCI358)

The causes and extent of regional inequality in the process of economic growth are at the core of historical economic research. So far, much attention has been devoted to studying the role of industrialization in driving regional divergence. However, empirical studies on relatively unequal countries such as Italy and Spain show that inequality was already high at the outset of modern industrializa

This paper revisits the Power Resource Theory (PRT) by testing one of its more influential claims: the relation between the strength of the labor movement and the reduction of industrial conflicts. Using panel data techniques to analyze more than 2,000 strikes in 103 Swedish towns we test whether a shift in the balance of power towards Social Democratic rule was associated with fewer strikes. The