Transposable elements (TEs) are dynamically expressed at high levels in multiple human tissues, but the function of TE-derived transcripts remains largely unknown. In this study, we identify numerous TE-derived microRNAs (miRNAs) by conducting Argonaute2 RNA immunoprecipitation followed by small RNA sequencing (AGO2 RIP-seq) on human brain tissue. Many of these miRNAs originated from LINE-2 (L2) e

Introduction Including the patient perspective is important to achieve optimal outcomes in the treatment of rheumatoid arthritis (RA). Ample qualitative studies exist on patient outcomes in RA. A Belgian study recently unravelled what matters most to patients throughout the overwhelming and rapidly evolving early stage of RA. The present study, European Qualitative research project on Patient-pref

The series of ternary polar intermetalllcs Eu(Zn 1-x Ge x ) 2 0≤x≤ 1) has been investigated and characterized by powder and single-crystal X-ray diffraction as well as physical property measurements. For 0.50(2) 0.75, respectively, orthorhombic KHg 2 -type and trigonal EuGe 2 -type phases occur as a second phase in mixtures with an AIB 2 -type phase. Diffraction of the x= 0.75(2) sample sh

Cd13-x;In7Sb10 (x≈2.7, Y≈ 1.5) was synthesized in the form of millsized crystals from reaction mixtures containing excess cadmium. The intermetallic compound crystallizes in the rhombohedral space group R3m with α = 12.9704(4), c= 12.9443(5) Å, V= 1886.0(1) Å3, Z=3 and is isostructural to thermoelectric ß-Zn 4Sb3 and ßCd4Sb3. However, in contrast to these last two compounds Cd13-xInySb 10 is free

The structure of stistaite -SbSn, was investigated by single crystal X-ray diffraction and EDX to yield a simple relation between the modulated structure and the composition. Stistaite is found to be ineommensurately ordered over the entire stability region.

Ag0.98CaGe1.02, orthorhombic, Pnma (no. 62), a = 21.5602(5) Å, b = 4.5625(2) Å, c = 7.8713(2) Å, V = 774.3 Å3, Z = 12, Rgt(F) = 0.021, wRref(F 2) = 0.046, T=293 K.

A new binary phase, Cu10In7, was found during the investigation of the η?-phase field in the Cu-In system. Single crystals of Cu10In7 were grown from a melt under an inert atmosphere. The compound crystallizes in the monoclinic space group C2/m with cell parameters a = 13.8453(2)A ° , b = 11.8462(1)A ° , c = 6.7388(1)A ° and ?β = 91.063(1). The structure is based on a unit of face-sharing octahedr

The CoSn structure type contains large interstitial void spaces that frequently host electropositive guest atoms, such as rare earth elements. In this stuffing process, an intriguing ordering occurs between the neighboring void spaces leading to a family of long-period superstructures comprising intergrowths of the ScFe6Ge6 and ScFe6Ga 6 structure types. This superstucture ordering culminates in i

Using infrared reflection spectroscopy the authors show that the phase transitions from disordered high temperature Β- Zn4 Sb3 into the increasingly higher ordered and complex structured low-temperature phases α and α′ are accompanied by a significant increase in the free charge carrier density and a concomitant increase of the effective scattering rate.

The crystal structures of approximants RECd6 (RE = Tb, Ho, Er, Tm and Lu) have been refined from single crystal X-ray diffraction data. This work is a continuation of a previous study of MCdg approximants [1] in which the different types of disorder of the central Cd4 tetrahedra located in the dodecahedral cavities were examined. The structures of the title compounds are all similar to GdCd6 and d

The crystal structure of Sb8O11Cl2 (onoratoite) is redetermined in the triclinic space group P-1. The crystal structure was previously described by a partially disordered model in the monoclinic space group C 2 / m containing some partially occupied oxygen atoms. The new structural model features exclusively atomic positions that are fully occupied. The crystal structure was solved from single cry

Trivalent lanthanide-like metal ions coordinate nine water oxygen atoms, which form a tricapped trigonal prism in a large number of crystalline hydrates. Water deficiency, randomly distributed over the capping positions, was found for the smallest metal ions in the isomorphous nonahydrated trifluoromethanesulfonates, [M-(H2O)n](CF 3SO3)3, in which M = ScIII, Lu III, YbIII, TmIII or ErIII. The hydr

The peeling of an onion: Embedded in the voids of an infinite cationic [Te32Ni30X3O90]5+ network lies an icosahedral [Ni4X13]5- anionic guest cluster (ochre). It may be considered wrapped and trapped in a successive series of concentric skins made from the lone pairs of Te atoms (blue), the Te (yellow), O (red), and Ni atoms (light blue polyhedra). But are there any other guests?

The systems AeAl2-xMgx (Ae = Ca, Sr, Ba) display electron concentration induced Laves phase structural changes. However, the complete sequence MgCu2 → MgNi2 → MgZn 2 with increasing x (decreasing electron count) is only observed for Ae = Ca. Compounds SrAl2-xMgx (0 < x ≤ 2) and BaAl2-xMgx (x = 0.85 and 2.0) were synthesized and structurally characterized by X-ray diffraction experiments. For the S

The incommensurately modulated structure of ζ-Zn3-xSb 2 was solved and refined versus X-ray single crystal diffraction data using a 3+1 dimensional superspace formalism. The compound crystallizes in the orthorhombic system in the 3+1 dimensional superspace group Pnna(α0)0s0 with the cell parameters a=7.283(3)Å, b=15.398(5)Å, c=25.06(1)Å, q=(α,0,0), α≈0.385. The structure features columns of interg

β-Zn4Sb3 is an outstanding thermoelectric material mainly due to its extraordinarily low thermal conductivity, which is similar to that of glasses. Recently it was proposed that interstitial Zn atoms are responsible for this peculiar behavior. Here we report on the crystal and electronic stucture of the low-temperature polymorph α-Zn4Sb3. During the reversible phase transition the intricate disord

Single crystals of LaSeTe2 have been prepared by reaction of the elements in a LiCl/RbCl flux at 970 K for seven days. Satellite reflections observed in diffraction experiments indicate the presence of an incommensurate lattice distortion, which is of the charge-density-wave (CDW) type. The modulated structure has been solved from X-ray data at 173, 293, and 373 K. LaSeTe2 crystallizes in the 3+1-