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In degenerative adult onset ataxia (AOA), dystonic comorbidity is attributed to one disease continuum. However, in early adult onset ataxia (EOA), the prevalence and pathogenesis of dystonic comorbidity (EOAD+), are still unclear. In 80 EOA-patients, we determined the EOAD+-prevalence in association with MRI-abnormalities. Subsequently, we explored underlying biological pathways by genetic network
The jet energy scale, jet energy resolution, and their systematic uncertainties are measured for jets reconstructed with the ATLAS detector in 2012 using proton–proton data produced at a centre-of-mass energy of 8 TeV with an integrated luminosity of 20fb-1. Jets are reconstructed from clusters of energy depositions in the ATLAS calorimeters using the anti-kt algorithm. A jet calibration scheme is
På kort tid har coronapandemin utlöst en djup ekonomisk kris i Sverige. Härpresenterar vi en första obduktion av krisen. Vi jämför dagens krisförlopp medde två senaste kriserna, finanskrisen 1991–93 och den internationella finanskrisen 2008–09. Vi kartlägger hur svensk ekonomi har påverkats samt belyser de kortsiktiga samhällsekonomiska kriskostnaderna. Därefter beskrivs krispolitiken. Här ställs
This study investigates the use of a direct ground cooling system (DGCS) using active chilled beams for the cooling of office buildings in Sweden. The methodology of the study entails laboratory experiments to develop and validate a simulation model of the cooling system. The sensitivity of the input parameters, such as borehole heat exchanger (BHE) length, internal heat gains and room temperature
We harness big data to detect prime locations---large clusters of know-ledge-based tradable services---in 125 global cities and track changes in the within-city geography of prime service jobs over a century. Historically smaller cities that did not develop early public transit networks are less concentrated today and have prime locations farther away from their historic cores. We rationalize thes
Här presenteras de senaste besluten av BirdLife Sveriges Taxonomi kommitté. Detta är en förkortad version, den fullständiga rapporten med mer detaljer, referenser och extralimitala förändringar finns på Tk:s hemsida under ”Rapporter”. I denna omgång utökas inte Sverigelistan med nya arter, dock urskiljs ett antal som mycket väl kan uppträda i Sverige i framtiden. Flera välkända svenska häckfåglar
The Swedish public unemployment insurance program is characterized by its governance structure involving union-linked insurance funds, famously known as the Ghent system. This paper argues that the unions’ strongly entrenched interest in the provision of unemployment benefits has continued to shape the establishment and expansion of complementary benefits for the unemployed in multiple forms, incl
Will technical change spur conflicts in the labor market? In this study, we examine electricity adoption in Sweden during the first decades of the twentieth century. Exploiting that proximity to hydropowered plants shaped the electricity network independently of previous local conditions, we estimate the impact of electricity on labor strikes. Our results indicate that electricity adoption precede
In Alzheimer's disease (AD), the Braak staging scheme suggests a stereotypical tau spreading pattern that does, however, not capture interindividual variability in tau deposition. This complicates the prediction of tau spreading, which may become critical for defining individualized tau-PET readouts in clinical trials. Since tau is assumed to spread throughout connected regions, we used functional
Bone morphogenic proteins (BMPs) are the only true osteoinductive molecules. Despite being tremendously potent, their clinical use has been limited for reasons including supraphysiological doses, suboptimal delivery systems, and the pro-osteoclast effect of BMPs. Efforts to achieve spatially controlled bone formation using BMPs are being made. We demonstrate that a carrier consisting of a powder o
The solubility of quercetin and its thermal degradation was studied in CO2-expanded ethanol and ethyl lactate. An equipment setup was constructed that enabled the separation of the products of degradation while quantifying the solubility of quercetin. Three different conditions of temperature were analyzed (308, 323, and 343 K) at 10 MPa. Higher solubility and thermal degradation of quercetin were
Drought and agricultural management influence soil microorganisms with unknown consequences for the functioning of agroecosystems. We simulated drought periods in organic (biodynamic) and conventional wheat fields and monitored effects on soil water content, microorganisms and crops. Above the wilting point, water content and microbial respiration were higher under biodynamic than conventional far
Objectives Patients ≥65 years old represent 30%-50% of all ambulance assignments (AAs), and the knowledge of which care level they are disposed to is limited and diverging. The aim of this study was therefore to describe and compare characteristics of patients' aged ≥65 years dispositions during AA, including determining changes over time and factors associated with non-conveyance to hospitals. De
